Folding project #16568, LIQUID-PHASE-SEPARATION research

Research section Research projects and references

Project #16568 overview

Project Summary AI Beta

This project simulates how liquids separate into different parts (like oil and water) when certain molecules are added. Researchers looked at how adding specific peptides (small proteins) affects this separation, both with and without RNA (genetic material).

Automated summary; simplified and may not be fully accurate.

Project team

Manager(s): Prof. Xuhui Huang
Institution: Hong Kong University of Science and Technology

Work unit

Atoms: 225,706
Core: 0x22
Status: Public

Source material

Official Project Description

16550: Liquid-liquid Phase separation simulation for condensate and added peptide ADMA 16551, 16560, 16568: Liquid-liquid Phase separation simulation for condensate and added peptide ADMA 16552, 16561, 16567: Liquid-liquid Phase separation simulation for condensate and added peptide ARG 16553, 16562, 16569: Liquid-liquid Phase separation simulation for condensate and added peptide LYS 16554: Liquid-liquid Phase separation simulation for condensate containing peptide ADMA and RNA 16555, 16576: Liquid-liquid Phase separation simulation for condensate containing peptide ARG and RNA 16556: Liquid-liquid Phase separation simulation for condensate containing peptide LYS and RNA 16557, 16563, 16572: Liquid-liquid Phase separation simulation for condensate containing peptide ADMA and RNA, concentration 3.7 mM 16558, 16564, 16566, 16571: Liquid-liquid Phase separation simulation for condensate containing peptide ARG and RNA, concentration 3.7 mM 16559, 16565, 16573: Liquid-liquid Phase separation simulation for condensate containing peptide LYS and RNA, concentration 3.7 mM 16570.

Reading reference

Related Terms Glossary AI Beta

Automated high-level definitions; simplified and may not be fully accurate.

Liquid-liquid Phase separation

The process by which two immiscible liquids separate into distinct phases.

Scientific: Life SciencesBiotechnology / Molecular Biology

Liquid-liquid phase separation is a natural phenomenon where two liquids, unable to mix, divide into layers. This is important in biology because many cellular processes involve the formation of distinct compartments within cells using this principle.

Condensate

A concentrated solution or mixture of substances, often formed by phase separation.

Scientific: Life SciencesBiotechnology / Molecular Biology

In biology, a condensate is a dense, droplet-like structure within cells that forms when certain molecules clump together. These droplets can play important roles in organizing cellular processes and storing information.

Peptide

A short chain of amino acids linked together.

Scientific: Life SciencesBiotechnology / Molecular Biology, Biochemistry

Peptides are like tiny chains made up of building blocks called amino acids. They play many crucial roles in the body, including carrying signals, defending against infections, and helping to build and repair tissues.

ADMA

Aspartate-dimethylarginine dimethylaminohydrolase (amino acid metabolism)

Technical: HealthcareBiotechnology / Pharmacology, Biochemistry

ADMA is a molecule that can affect blood vessel function. It's related to the metabolism of amino acids and plays a role in how our blood vessels expand and contract.

ARG

Arginine (amino acid)

Technical: HealthcareBiotechnology / Pharmacology, Biochemistry

Arginine is an essential amino acid that our bodies need to function properly. It's involved in many processes, including building proteins, producing nitric oxide (which helps blood vessels relax), and supporting the immune system.

LYS

Lysine (amino acid)

Technical: HealthcareBiotechnology / Pharmacology, Biochemistry

Lysine is another essential amino acid that plays a vital role in building proteins, producing enzymes, and supporting healthy growth and development.

RNA

Ribonucleic acid, a nucleic acid that plays a crucial role in protein synthesis.

Scientific: Life SciencesBiotechnology / Molecular Biology

RNA is a molecule essential for making proteins. It carries genetic information from DNA to the ribosomes, where proteins are built.

GPU PPD Averages

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 4090 AD102 [GeForce RTX 4090]	Nvidia	AD102	19,765,154	518,888	38.09	0 ^hrs 38 ^mins
2	GeForce RTX 4080 AD103 [GeForce RTX 4080]	Nvidia	AD103	14,697,030	474,820	30.95	0 ^hrs 47 ^mins
3	GeForce RTX 4070 Ti AD104 [GeForce RTX 4070 Ti]	Nvidia	AD104	11,518,225	430,475	26.76	0 ^hrs 54 ^mins
4	GeForce RTX 3090 Ti GA102 [GeForce RTX 3090 Ti]	Nvidia	GA102	8,765,360	393,904	22.25	1 ^hrs 5 ^mins
5	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	8,432,329	391,745	21.53	1 ^hrs 7 ^mins
6	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	7,637,103	379,113	20.14	1 ^hrs 11 ^mins
7	GeForce RTX 3080 12GB GA102 [GeForce RTX 3080 12GB]	Nvidia	GA102	7,094,019	370,176	19.16	1 ^hrs 15 ^mins
8	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	6,825,385	368,542	18.52	1 ^hrs 18 ^mins
9	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	6,616,289	358,704	18.44	1 ^hrs 18 ^mins
10	GeForce RTX 4070 AD104 [GeForce RTX 4070]	Nvidia	AD104	6,394,673	362,277	17.65	1 ^hrs 22 ^mins
11	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	5,678,319	346,381	16.39	1 ^hrs 28 ^mins
12	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	5,197,560	337,059	15.42	1 ^hrs 33 ^mins
13	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	5,126,668	336,010	15.26	1 ^hrs 34 ^mins
14	GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate]	Nvidia	GA104	4,443,607	319,445	13.91	1 ^hrs 44 ^mins
15	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	3,668,163	298,927	12.27	1 ^hrs 57 ^mins
16	Radeon RX 7900XT/XTX Navi 31 [Radeon RX 7900XT/XTX]	AMD	Navi 31	3,594,584	293,072	12.27	1 ^hrs 57 ^mins
17	GeForce GTX 960 GM206 [GeForce GTX 960] 2308	Nvidia	GM206	3,570,027	153,708	23.23	1 ^hrs 2 ^mins
18	Radeon RX 6900 XT Navi 21 [Radeon RX 6900 XT]	AMD	Navi 21	3,477,835	294,947	11.79	2 ^hrs 2 ^mins
19	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	3,378,358	292,194	11.56	2 ^hrs 5 ^mins

20	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	3,278,882	289,084	11.34	2 ^hrs 7 ^mins
21	GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068	Nvidia	TU104	3,229,528	286,145	11.29	2 ^hrs 8 ^mins
22	GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A]	Nvidia	TU106	3,173,101	285,945	11.10	2 ^hrs 10 ^mins
23	GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate]	Nvidia	GA104	3,108,798	279,496	11.12	2 ^hrs 9 ^mins
24	GeForce RTX 3070 Mobile / Max-Q GA104M [GeForce RTX 3070 Mobile / Max-Q]	Nvidia	GA104M	2,888,159	277,580	10.40	2 ^hrs 18 ^mins
25	GeForce RTX 3060 GA104 [GeForce RTX 3060]	Nvidia	GA104	2,760,730	273,307	10.10	2 ^hrs 23 ^mins
26	GeForce RTX 2080 TU104 [GeForce RTX 2080]	Nvidia	TU104	2,591,945	266,486	9.73	2 ^hrs 28 ^mins
27	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,560,770	262,759	9.75	2 ^hrs 28 ^mins
28	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	2,531,101	393,238	6.44	3 ^hrs 44 ^mins
29	RTX A4000 GA104GL [RTX A4000]	Nvidia	GA104GL	2,474,732	259,082	9.55	2 ^hrs 31 ^mins
30	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	2,394,904	261,348	9.16	2 ^hrs 37 ^mins
31	GeForce RTX 2070 TU106 [GeForce RTX 2070]	Nvidia	TU106	2,320,973	253,966	9.14	2 ^hrs 38 ^mins
32	GeForce RTX 3060 GA106 [GeForce RTX 3060]	Nvidia	GA106	2,317,533	257,550	9.00	2 ^hrs 40 ^mins
33	Radeon RX 6800/6800XT/6900XT Navi 21 [Radeon RX 6800/6800XT/6900XT]	AMD	Navi 21	2,227,494	250,267	8.90	2 ^hrs 42 ^mins
34	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,221,885	244,682	9.08	2 ^hrs 39 ^mins
35	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	2,165,329	246,737	8.78	2 ^hrs 44 ^mins
36	GeForce RTX 2060 TU106 [Geforce RTX 2060]	Nvidia	TU106	1,910,740	239,739	7.97	3 ^hrs 1 ^mins
37	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,602,269	228,031	7.03	3 ^hrs 25 ^mins
38	GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q]	Nvidia	GA106M	1,532,829	225,508	6.80	3 ^hrs 32 ^mins
39	GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti]	Nvidia	TU116	1,376,685	217,149	6.34	3 ^hrs 47 ^mins

40	RTX A2000 GA106 [RTX A2000]	Nvidia	GA106	1,276,368	211,252	6.04	3 ^hrs 58 ^mins
41	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,261,138	208,126	6.06	3 ^hrs 58 ^mins
42	Radeon RX 6700/6700XT/6800M Navi 22 XT-XL [Radeon RX 6700/6700XT/6800M]	AMD	Navi 22 XT-XL	1,238,589	201,727	6.14	3 ^hrs 55 ^mins
43	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	1,209,525	207,249	5.84	4 ^hrs 7 ^mins
44	GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632	Nvidia	GM200	1,168,300	195,924	5.96	4 ^hrs 1 ^mins
45	Radeon RX 6650XT Navi 23 [Radeon RX 6650XT]	AMD	Navi 23	1,143,437	204,234	5.60	4 ^hrs 17 ^mins
46	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	1,042,432	196,467	5.31	4 ^hrs 31 ^mins
47	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,020,156	194,550	5.24	4 ^hrs 35 ^mins
48	P104-100 GP104 [P104-100]	Nvidia	GP104	999,723	195,774	5.11	4 ^hrs 42 ^mins
49	GeForce GTX 980 GM204 [GeForce GTX 980] 4612	Nvidia	GM204	706,160	175,680	4.02	5 ^hrs 58 ^mins
50	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	638,056	176,147	3.62	6 ^hrs 38 ^mins
51	GeForce GTX 1650 TU117 [GeForce GTX 1650]	Nvidia	TU117	585,814	163,450	3.58	6 ^hrs 42 ^mins
52	GeForce GTX 970 GM204 [GeForce GTX 970] 3494	Nvidia	GM204	577,661	165,207	3.50	6 ^hrs 52 ^mins
53	Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64]	AMD	Vega 10 XL/XT	314,954	147,434	2.14	11 ^hrs 14 ^mins
54	P106-090 GP106 [P106-090]	Nvidia	GP106	298,572	130,741	2.28	10 ^hrs 31 ^mins
55	GeForce GTX 950 GM206 [GeForce GTX 950] 1572	Nvidia	GM206	249,828	123,318	2.03	11 ^hrs 51 ^mins
56	GeForce GTX 1050 Mobile GP107M [GeForce GTX 1050 Mobile]	Nvidia	GP107M	239,864	115,800	2.07	11 ^hrs 35 ^mins
57	GeForce MX450 TU117M [GeForce MX450]	Nvidia	TU117M	235,920	119,968	1.97	12 ^hrs 12 ^mins
58	Quadro P1000 GP107GL [Quadro P1000]	Nvidia	GP107GL	215,157	116,869	1.84	13 ^hrs 2 ^mins
59	Quadro P2200 GP106GL [Quadro P2200]	Nvidia	GP106GL	178,848	87,555	2.04	11 ^hrs 45 ^mins

60	GeForce GTX 1050 LP GP107 [GeForce GTX 1050 LP] 1862	Nvidia	GP107	166,079	112,526	1.48	16 ^hrs 16 ^mins
61	GeForce GTX 750 Ti GM107 [GeForce GTX 750 Ti] 1389	Nvidia	GM107	119,986	104,219	1.15	20 ^hrs 51 ^mins
62	GeForce GT 1030 GP108 [GeForce GT 1030]	Nvidia	GP108	110,119	93,630	1.18	20 ^hrs 24 ^mins
63	Quadro K2200 GM107GL [Quadro K2200]	Nvidia	GM107GL	105,147	98,099	1.07	22 ^hrs 23 ^mins
64	Quadro K1200 GM107GL [Quadro K1200]	Nvidia	GM107GL	52,847	73,219	0.72	33 ^hrs 15 ^mins
65	Quadro K620 GM107GL [Quadro K620]	Nvidia	GM107GL	43,997	73,480	0.60	40 ^hrs 5 ^mins
66	GeForce GTX 745 GM107 [GeForce GTX 745] 793	Nvidia	GM107	42,537	71,615	0.59	40 ^hrs 24 ^mins

Research: LIQUID-PHASE-SEPARATION Folding Project #16568

Project Summary AI Beta

Project team

Work unit

Official Project Description

Hardware Performance for Project 16568

GPU PPD Averages

Research: LIQUID-PHASE-SEPARATION Folding Project #16568

Project Summary AI Beta

Project team

Work unit

Related projects

GPU PPD Averages