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Research: DIABETES Folding Project #14917

Project #14917 overview

Project Summary AI Beta

This project looks at how certain proteins in our bodies change shape. These proteins (like the ones involved in diabetes and bone health) can be targeted by drugs. Understanding their movements could help create better medicines.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Prateek Bansal
Institution
University of Illinois Urbana-Champaign

Work unit

Atoms
109,533
Core
OPENMM_22
Status
Public
Source material

Official Project Description

G-Protein Coupled Receptors: G-Protein coupled receptors (GPCRs) are membrane proteins involved in the pathogenesis of diabetes, high blood pressure, osteoporosis, etc.

Here, we are trying to study the conformational dynamics of the Glucagon Receptor, Glucagon-like Peptide 1 receptor, PArathyroid Hormone Receptor, Pituitary Adenlyate Cyclase Receptor and Secretin Receptor - All Class B GPCRs.

These studies will help in designing better drugs that target these receptors.

Performance data

Hardware Performance for Project 14917

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:06:06

GPU PPD Averages

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average
1 Radeon VII
Vega 20 [Radeon VII] 13,284		 AMD Vega 20 1,357,203 86,591 15.67 1 hrs 32 mins
2 Radeon RX Vega 56/64
Vega 10 XL/XT [Radeon RX Vega 56/64]		 AMD Vega 10 XL/XT 849,816 72,502 11.72 2 hrs 3 mins
3 Radeon RX 470/480/570/580/590
Ellesmere XT [Radeon RX 470/480/570/580/590]		 AMD Ellesmere XT 290,952 47,434 6.13 3 hrs 55 mins