PROJECT #19002 RESEARCH FOR CANNABINOID
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

Cannabinoid Receptors The endocannabinoid signaling system consists of receptors (Cannabinoid Receptors; CB1 and CB2), endogeneous molecules (Endocannabinoids; 2-AG, Anandamide), and enzymes.

Endocannabinoids are produced in postsynaptic neurons and bind to Cannabinoid Receptors to maintain homeostasis in neuron signaling and a plethora of physiological processes.

These receptors are targeted for pain, obesity, and other central nervous system disorders.

Endocannabinoids show more than 10-fold selectivity towards CB1 compared to CB2.

Therefore, a mechanistic understanding of endocannabinoid selectivity will help us design selective therapeutics.

In this project, we are running binding simulation of anandmide to CB1 and CB2 to decipher ligand selectivity..

PROJECT INFO

Manager(s): Soumajit Dutta

Institution: University of Illinois Urbana-Champaign

Project URL: shuklagroup.org/

PROJECT WORK UNIT SUMMARY

Atoms: 98,432

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 16 May 2022 12:52:29

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	8,504,756	174,931	48.62	0 ^hrs 30 ^mins
2	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	7,429,384	165,584	44.87	1 ^hrs 32 ^mins
3	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	6,709,514	161,290	41.60	1 ^hrs 35 ^mins
4	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	4,676,697	142,272	32.87	1 ^hrs 44 ^mins
5	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	4,522,465	141,141	32.04	1 ^hrs 45 ^mins
6	RTX A5000 GA102GL [RTX A5000]	Nvidia	GA102GL	4,495,810	140,117	32.09	1 ^hrs 45 ^mins
7	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	4,157,352	136,983	30.35	1 ^hrs 47 ^mins
8	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	3,471,119	128,362	27.04	1 ^hrs 53 ^mins
9	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	2,844,240	122,837	23.15	1 ^hrs 2 ^mins
10	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,432,958	113,292	21.48	1 ^hrs 7 ^mins
11	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	2,103,404	109,809	19.16	1 ^hrs 15 ^mins
12	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	1,767,272	91,548	19.30	1 ^hrs 15 ^mins
13	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,535,474	98,526	15.58	2 ^hrs 32 ^mins
14	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,130,454	88,183	12.82	2 ^hrs 52 ^mins
15	GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935	Nvidia	GP106	616,614	73,903	8.34	3 ^hrs 53 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 16 May 2022 12:52:29

Rank Project	CPU Model	Logical Processors (LP)	PPD-PLP AVG PPD per 1 LP	ALL LP-PPD (Estimated)	Make

Legal Information: This sites use is for entertainment purposes only and comes with no guarantees or warranties in its use or related to any data displayed, collected or calcuated. This site is not affilated with folding@home or any folding team or GPU / CPU company in any official capacity and is an enthusiast creation in support of folding@home and the users / teams folding data for the greater good.

Please Note: By using this site, and / or our chrome extension you understand that you may be periodically providing information such as your IP, stats regarding use of our site, and folding@home GPU / CPU model, Work Unit ID and PPD estimate data when using our Chrome extention to the site developer for site optimization and PPD related data displayed on the site.

IF YOU DO NOT WISH TO CONTRIBUTE DATA TO THE PPD DATABASE PLEASE UNINSTALL OUR PLUGIN/TOOLS AND DISCONTINUE USE OF THIS SITE IMMEDIATELY.