PROJECT #19002 RESEARCH FOR CANNABINOID
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

Cannabinoid Receptors The endocannabinoid signaling system consists of receptors (Cannabinoid Receptors; CB1 and CB2), endogeneous molecules (Endocannabinoids; 2-AG, Anandamide), and enzymes.

Endocannabinoids are produced in postsynaptic neurons and bind to Cannabinoid Receptors to maintain homeostasis in neuron signaling and a plethora of physiological processes.

These receptors are targeted for pain, obesity, and other central nervous system disorders.

Endocannabinoids show more than 10-fold selectivity towards CB1 compared to CB2.

Therefore, a mechanistic understanding of endocannabinoid selectivity will help us design selective therapeutics.

In this project, we are running binding simulation of anandmide to CB1 and CB2 to decipher ligand selectivity..

PROJECT INFO

Manager(s): Soumajit Dutta

Institution: University of Illinois Urbana-Champaign

Project URL: shuklagroup.org/

PROJECT WORK UNIT SUMMARY

Atoms: 98,432

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 02 October 2022 12:16:25

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average
1 GeForce RTX 3090 Ti
GA102 [GeForce RTX 3090 Ti]
Nvidia GA102 8,501,154 174,407 48.74 0 hrs 30 mins
2 GeForce RTX 3090
GA102 [GeForce RTX 3090]
Nvidia GA102 7,950,207 170,214 46.71 1 hrs 31 mins
3 GeForce RTX 3080 Ti
GA102 [GeForce RTX 3080 Ti]
Nvidia GA102 6,536,590 159,102 41.08 1 hrs 35 mins
4 GeForce RTX 3080
GA102 [GeForce RTX 3080]
Nvidia GA102 6,390,741 158,992 40.20 1 hrs 36 mins
5 GeForce RTX 3080 Lite Hash Rate
GA102 [GeForce RTX 3080 Lite Hash Rate]
Nvidia GA102 6,183,278 155,215 39.84 1 hrs 36 mins
6 GeForce RTX 2080 Ti Rev. A
TU102 [GeForce RTX 2080 Ti Rev. A] M 13448
Nvidia TU102 4,771,115 143,553 33.24 1 hrs 43 mins
7 GeForce RTX 2080 Ti
TU102 [GeForce RTX 2080 Ti] M 13448
Nvidia TU102 4,549,956 141,537 32.15 1 hrs 45 mins
8 RTX A5000
GA102GL [RTX A5000]
Nvidia GA102GL 4,389,720 139,505 31.47 1 hrs 46 mins
9 GeForce RTX 3070 Ti
GA104 [GeForce RTX 3070 Ti]
Nvidia GA104 4,240,419 136,856 30.98 1 hrs 46 mins
10 GeForce RTX 3070 Lite Hash Rate
GA104 [GeForce RTX 3070 Lite Hash Rate]
Nvidia GA104 4,040,134 135,756 29.76 1 hrs 48 mins
11 GeForce RTX 3070
GA104 [GeForce RTX 3070]
Nvidia GA104 3,465,063 124,508 27.83 1 hrs 52 mins
12 Quadro RTX 6000/8000
TU102GL [Quadro RTX 6000/8000]
Nvidia TU102GL 3,302,286 127,380 25.92 1 hrs 56 mins
13 GeForce RTX 3060 Ti Lite Hash Rate
GA104 [GeForce RTX 3060 Ti Lite Hash Rate]
Nvidia GA104 3,182,983 124,097 25.65 1 hrs 56 mins
14 GeForce RTX 2080 Super
TU104 [GeForce RTX 2080 SUPER]
Nvidia TU104 3,121,423 124,463 25.08 1 hrs 57 mins
15 GeForce RTX 2070 SUPER
TU104 [GeForce RTX 2070 SUPER] 8218
Nvidia TU104 2,892,129 122,717 23.57 1 hrs 1 mins
16 GeForce RTX 3060 Ti
GA104 [GeForce RTX 3060 Ti]
Nvidia GA104 2,844,240 122,837 23.15 1 hrs 2 mins
17 GeForce RTX 3070 Mobile / Max-Q
GA104M [GeForce RTX 3070 Mobile / Max-Q]
Nvidia GA104M 2,788,067 120,775 23.08 1 hrs 2 mins
18 GeForce GTX 1080 Ti
GP102 [GeForce GTX 1080 Ti] 11380
Nvidia GP102 2,320,205 112,979 20.54 1 hrs 10 mins
19 GeForce RTX 2080
TU104 [GeForce RTX 2080]
Nvidia TU104 2,203,412 111,687 19.73 1 hrs 13 mins
20 GeForce RTX 2060 Super
TU106 [GeForce RTX 2060 SUPER]
Nvidia TU106 2,049,800 107,134 19.13 1 hrs 15 mins
21 GeForce RTX 2060
TU106 [Geforce RTX 2060]
Nvidia TU106 1,967,569 106,055 18.55 1 hrs 18 mins
22 GeForce RTX 3060
GA104 [GeForce RTX 3060]
Nvidia GA104 1,903,300 106,339 17.90 1 hrs 20 mins
23 GeForce RTX 3060 Lite Hash Rate
GA106 [GeForce RTX 3060 Lite Hash Rate]
Nvidia GA106 1,755,413 100,346 17.49 1 hrs 22 mins
24 Quadro RTX 4000
TU104GL [Quadro RTX 4000]
Nvidia TU104GL 1,754,518 103,312 16.98 1 hrs 25 mins
25 GeForce RTX 3060 Mobile / Max-Q
GA106M [GeForce RTX 3060 Mobile / Max-Q]
Nvidia GA106M 1,700,340 102,171 16.64 1 hrs 27 mins
26 GeForce RTX 2070
TU106 [GeForce RTX 2070]
Nvidia TU106 1,622,161 100,884 16.08 1 hrs 30 mins
27 GeForce GTX 1080
GP104 [GeForce GTX 1080] 8873
Nvidia GP104 1,454,218 96,837 15.02 2 hrs 36 mins
28 GeForce RTX 2060 Mobile
TU106M [GeForce RTX 2060 Mobile]
Nvidia TU106M 1,332,410 93,569 14.24 2 hrs 41 mins
29 Geforce RTX 3050
GA106 [Geforce RTX 3050]
Nvidia GA106 1,250,541 91,527 13.66 2 hrs 45 mins
30 GeForce RTX 2060
TU104 [GeForce RTX 2060]
Nvidia TU104 1,199,174 91,032 13.17 2 hrs 49 mins
31 GeForce GTX 1660 SUPER
TU116 [GeForce GTX 1660 SUPER]
Nvidia TU116 1,178,887 89,611 13.16 2 hrs 49 mins
32 GeForce GTX 1070 Ti
GP104 [GeForce GTX 1070 Ti] 8186
Nvidia GP104 1,170,601 90,380 12.95 2 hrs 51 mins
33 GeForce GTX 1660 Mobile
TU116M [GeForce GTX 1660 Mobile]
Nvidia TU116M 1,103,032 88,586 12.45 2 hrs 56 mins
34 GeForce GTX 1070
GP104 [GeForce GTX 1070] 6463
Nvidia GP104 1,020,897 84,490 12.08 2 hrs 59 mins
35 P104-100
GP104 [P104-100]
Nvidia GP104 844,550 81,657 10.34 2 hrs 19 mins
36 GeForce GTX 1660
TU116 [GeForce GTX 1660]
Nvidia TU116 701,367 71,529 9.81 2 hrs 27 mins
37 GeForce GTX 1060 6GB
GP106 [GeForce GTX 1060 6GB] 4372
Nvidia GP106 657,449 74,986 8.77 3 hrs 44 mins
38 GeForce GTX 1060 3GB
GP106 [GeForce GTX 1060 3GB] 3935
Nvidia GP106 616,614 73,903 8.34 3 hrs 53 mins
39 GeForce GTX 1650
TU117 [GeForce GTX 1650]
Nvidia TU117 541,988 69,995 7.74 3 hrs 6 mins
40 GeForce GTX 980
GM204 [GeForce GTX 980] 4612
Nvidia GM204 513,510 68,760 7.47 3 hrs 13 mins
41 GeForce GTX 1650 Mobile / Max-Q
TU117M [GeForce GTX 1650 Mobile / Max-Q]
Nvidia TU117M 464,689 65,274 7.12 3 hrs 22 mins
42 P106-090
GP106 [P106-090]
Nvidia GP106 283,949 56,401 5.03 5 hrs 46 mins
43 Quadro M4000
GM204GL [Quadro M4000]
Nvidia GM204GL 270,956 56,451 4.80 5 hrs 0 mins
44 GeForce GTX 960
GM206 [GeForce GTX 960] 2308
Nvidia GM206 267,316 49,878 5.36 4 hrs 29 mins
45 GeForce GTX 1050 Ti
GP107 [GeForce GTX 1050 Ti] 2138
Nvidia GP107 254,711 56,515 4.51 5 hrs 20 mins
46 GeForce GTX 950
GM206 [GeForce GTX 950] 1572
Nvidia GM206 219,658 52,212 4.21 6 hrs 42 mins
47 Quadro P1000
GP107GL [Quadro P1000]
Nvidia GP107GL 193,183 49,704 3.89 6 hrs 10 mins
48 GeForce GTX 750 Ti
GM107 [GeForce GTX 750 Ti] 1389
Nvidia GM107 120,238 42,485 2.83 8 hrs 29 mins
49 GeForce GT 1030
GP108 [GeForce GT 1030] 1127
Nvidia GP108 98,764 39,754 2.48 10 hrs 40 mins
50 GeForce GT 1030
GP108 [GeForce GT 1030]
Nvidia GP108 91,947 38,768 2.37 10 hrs 7 mins
51 Quadro K2200
GM107GL [Quadro K2200]
Nvidia GM107GL 79,330 38,802 2.04 12 hrs 44 mins
52 Quadro K620
GM107GL [Quadro K620]
Nvidia GM107GL 44,620 30,479 1.46 16 hrs 24 mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 02 October 2022 12:16:25

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make