PROJECT #19001 RESEARCH FOR CANNABINOID
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

Cannabinoid Receptors The endocannabinoid signaling system consists of receptors (Cannabinoid Receptors; CB1 and CB2), endogeneous molecules (Endocannabinoids; 2-AG, Anandamide), and enzymes.

Endocannabinoids are produced in postsynaptic neurons and bind to Cannabinoid Receptors to maintain homeostasis in neuron signaling and a plethora of physiological processes.

These receptors are targeted for pain, obesity, and other central nervous system disorders.

Endocannabinoids show more than 10-fold selectivity towards CB1 compared to CB2.

Therefore, a mechanistic understanding of endocannabinoid selectivity will help us design selective therapeutics.

In this project, we are running binding simulation of anandmide to CB1 and CB2 to decipher ligand selectivity..

PROJECT INFO

Manager(s): Soumajit Dutta

Institution: University of Illinois Urbana-Champaign

Project URL: shuklagroup.org/

PROJECT WORK UNIT SUMMARY

Atoms: 103,284

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 22 May 2022 15:22:29

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average
1 GeForce RTX 3090 Ti
GA102 [GeForce RTX 3090 Ti]
Nvidia GA102 9,886,727 190,103 52.01 0 hrs 28 mins
2 GeForce RTX 3080 Lite Hash Rate
GA102 [GeForce RTX 3080 Lite Hash Rate]
Nvidia GA102 7,314,246 168,615 43.38 1 hrs 33 mins
3 GeForce RTX 3090
GA102 [GeForce RTX 3090]
Nvidia GA102 6,628,639 159,215 41.63 1 hrs 35 mins
4 GeForce RTX 3080 Ti
GA102 [GeForce RTX 3080 Ti]
Nvidia GA102 6,416,863 160,013 40.10 1 hrs 36 mins
5 GeForce RTX 3080
GA102 [GeForce RTX 3080]
Nvidia GA102 5,714,826 156,255 36.57 1 hrs 39 mins
6 GeForce RTX 2080 Ti Rev. A
TU102 [GeForce RTX 2080 Ti Rev. A] M 13448
Nvidia TU102 4,537,159 142,757 31.78 1 hrs 45 mins
7 RTX A5000
GA102GL [RTX A5000]
Nvidia GA102GL 4,464,860 142,954 31.23 1 hrs 46 mins
8 GeForce RTX 2080 Ti
TU102 [GeForce RTX 2080 Ti] M 13448
Nvidia TU102 4,406,738 142,472 30.93 1 hrs 47 mins
9 GeForce RTX 3070 Lite Hash Rate
GA104 [GeForce RTX 3070 Lite Hash Rate]
Nvidia GA104 4,394,345 143,812 30.56 1 hrs 47 mins
10 GeForce RTX 3070 Ti
GA104 [GeForce RTX 3070 Ti]
Nvidia GA104 4,247,188 139,076 30.54 1 hrs 47 mins
11 GeForce RTX 3070
GA104 [GeForce RTX 3070]
Nvidia GA104 3,947,661 137,276 28.76 1 hrs 50 mins
12 GeForce RTX 2080 Super
TU104 [GeForce RTX 2080 SUPER]
Nvidia TU104 3,285,314 129,539 25.36 1 hrs 57 mins
13 GeForce RTX 2070 SUPER
TU104 [GeForce RTX 2070 SUPER] 8218
Nvidia TU104 2,831,744 122,892 23.04 1 hrs 2 mins
14 GeForce RTX 3060 Ti Lite Hash Rate
GA104 [GeForce RTX 3060 Ti Lite Hash Rate]
Nvidia GA104 2,755,817 117,554 23.44 1 hrs 1 mins
15 GeForce RTX 3060 Ti
GA104 [GeForce RTX 3060 Ti]
Nvidia GA104 2,603,884 120,390 21.63 1 hrs 7 mins
16 GeForce RTX 3070 Mobile / Max-Q
GA104M [GeForce RTX 3070 Mobile / Max-Q]
Nvidia GA104M 2,323,671 115,009 20.20 1 hrs 11 mins
17 Tesla P100 16GB
GP100GL [Tesla P100 16GB] 9340
Nvidia GP100GL 2,278,956 115,442 19.74 1 hrs 13 mins
18 GeForce GTX 1080 Ti
GP102 [GeForce GTX 1080 Ti] 11380
Nvidia GP102 2,220,205 113,479 19.56 1 hrs 14 mins
19 GeForce RTX 2060 Super
TU106 [GeForce RTX 2060 SUPER]
Nvidia TU106 2,052,799 110,592 18.56 1 hrs 18 mins
20 GeForce RTX 3080 Mobile / Max-Q 8GB/16GB
GA104M [GeForce RTX 3080 Mobile / Max-Q 8GB/16GB]
Nvidia GA104M 1,723,922 104,182 16.55 1 hrs 27 mins
21 GeForce RTX 3060 Lite Hash Rate
GA106 [GeForce RTX 3060 Lite Hash Rate]
Nvidia GA106 1,658,570 101,649 16.32 1 hrs 28 mins
22 GeForce RTX 2060 Mobile
TU106M [GeForce RTX 2060 Mobile]
Nvidia TU106M 1,529,413 100,826 15.17 2 hrs 35 mins
23 GeForce RTX 2060
TU104 [GeForce RTX 2060]
Nvidia TU104 1,440,884 96,897 14.87 2 hrs 37 mins
24 GeForce GTX 1080
GP104 [GeForce GTX 1080] 8873
Nvidia GP104 1,338,959 96,109 13.93 2 hrs 43 mins
25 Geforce RTX 3050
GA106 [Geforce RTX 3050]
Nvidia GA106 1,213,672 93,407 12.99 2 hrs 51 mins
26 GeForce GTX 1070 Ti
GP104 [GeForce GTX 1070 Ti] 8186
Nvidia GP104 1,185,518 90,220 13.14 2 hrs 50 mins
27 GeForce GTX 980 Ti
GM200 [GeForce GTX 980 Ti] 5632
Nvidia GM200 1,158,483 91,364 12.68 2 hrs 54 mins
28 GeForce GTX 1660 SUPER
TU116 [GeForce GTX 1660 SUPER]
Nvidia TU116 1,035,693 86,417 11.98 2 hrs 0 mins
29 GeForce GTX 1660
TU116 [GeForce GTX 1660]
Nvidia TU116 1,014,032 86,040 11.79 2 hrs 2 mins
30 GeForce GTX 1070
GP104 [GeForce GTX 1070] 6463
Nvidia GP104 1,003,316 86,049 11.66 2 hrs 4 mins
31 Tesla M40
GM200GL [Tesla M40] 6844
Nvidia GM200GL 937,833 85,037 11.03 2 hrs 11 mins
32 GeForce GTX 1060 6GB
GP106 [GeForce GTX 1060 6GB] 4372
Nvidia GP106 705,326 78,196 9.02 3 hrs 40 mins
33 GeForce GTX 980
GM204 [GeForce GTX 980] 4612
Nvidia GM204 612,811 73,979 8.28 3 hrs 54 mins
34 GeForce GTX 970
GM204 [GeForce GTX 970] 3494
Nvidia GM204 533,222 70,556 7.56 3 hrs 11 mins
35 GeForce GTX 1060 3GB
GP106 [GeForce GTX 1060 3GB] 3935
Nvidia GP106 521,578 70,253 7.42 3 hrs 14 mins
36 Quadro M5000
GM204GL [Quadro M5000]
Nvidia GM204GL 412,254 65,541 6.29 4 hrs 49 mins
37 GeForce GTX 1650
TU117 [GeForce GTX 1650]
Nvidia TU117 380,029 63,717 5.96 4 hrs 1 mins
38 GeForce GTX 960
GM206 [GeForce GTX 960] 2308
Nvidia GM206 283,857 55,699 5.10 5 hrs 43 mins
39 GeForce GTX 980M
GM204 [GeForce GTX 980M] 3189
Nvidia GM204 272,900 56,034 4.87 5 hrs 56 mins
40 P106-090
GP106 [P106-090]
Nvidia GP106 270,311 56,416 4.79 5 hrs 1 mins
41 T600
TU117GL [T600]
Intel TU117GL 233,927 53,338 4.39 5 hrs 28 mins
42 GeForce GTX 1050 LP
GP107 [GeForce GTX 1050 LP] 1862
Nvidia GP107 215,292 52,414 4.11 6 hrs 51 mins
43 GeForce GTX 950
GM206 [GeForce GTX 950] 1572
Nvidia GM206 203,172 50,664 4.01 6 hrs 59 mins
44 GeForce GTX 750 Ti
GM107 [GeForce GTX 750 Ti] 1389
Nvidia GM107 114,250 42,331 2.70 9 hrs 54 mins
45 Quadro K2200
GM107GL [Quadro K2200]
Nvidia GM107GL 102,594 41,295 2.48 10 hrs 40 mins
46 GeForce GT 1030
GP108 [GeForce GT 1030] 1127
Nvidia GP108 93,031 39,480 2.36 10 hrs 11 mins
47 GeForce GTX 950M
GM107 [GeForce GTX 950M] 1439
Nvidia GM107 90,565 39,070 2.32 10 hrs 21 mins
48 Quadro K1200
GM107GL [Quadro K1200]
Nvidia GM107GL 50,609 32,398 1.56 15 hrs 22 mins
49 Quadro K620
GM107GL [Quadro K620]
Nvidia GM107GL 42,153 30,378 1.39 17 hrs 18 mins
50 Quadro P400
GP107GL [Quadro P400] 641
Nvidia GP107GL 20,386 21,300 0.96 25 hrs 5 mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 22 May 2022 15:22:29

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make