Research section Research projects and references

Research: PARKINSONS Folding Project #17915

Project #17915 overview

Project Summary AI Beta

This project uses computer simulations to study the serotonin transporter, a protein that affects mood and behavior. By looking at how changes in the transporter's structure affect its function, researchers hope to better understand mental disorders like depression and Parkinson's disease, and develop new treatments.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Matthew Chan
Institution
University of Illinois Urbana-Champaign

Work unit

Atoms
107,425
Core
OPENMM_22
Status
Public
Source material

Official Project Description

These projects contains simulations of the serotonin transporter, the protein responsible for terminating neurotransmission in neurons.

The neurotransmitter serotonin regulates various functions in the body such as mood, behavior, appettite, and sleep, and is a major drug targets for antidepressants.

Malfunctions in the serotonin transporter have been assoicated with mental disorders including depression and Parkinson's.

Our goal in performing these simulations is to understand how mutations affect the structure and dynamics of the serotonin transporter and provide insights to treat psychatric disorders assoicated with these mutations.

Performance data

Hardware Performance for Project 17915

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 21:55:17

GPU PPD Averages

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average
1 GeForce RTX 3090
GA102 [GeForce RTX 3090]
Nvidia GA102 8,188,684 422,705 19.37 1 hrs 14 mins
2 GeForce RTX 3080
GA102 [GeForce RTX 3080]
Nvidia GA102 7,385,663 409,442 18.04 1 hrs 20 mins
3 GeForce RTX 3080 Ti
GA102 [GeForce RTX 3080 Ti]
Nvidia GA102 7,059,577 402,577 17.54 1 hrs 22 mins
4 GeForce RTX 3070 Ti
GA104 [GeForce RTX 3070 Ti]
Nvidia GA104 4,564,721 347,282 13.14 1 hrs 50 mins
5 GeForce RTX 2080 Ti Rev. A
TU102 [GeForce RTX 2080 Ti Rev. A] M 13448
Nvidia TU102 4,515,431 345,345 13.08 1 hrs 50 mins
6 GeForce RTX 2080 Ti
TU102 [GeForce RTX 2080 Ti] M 13448
Nvidia TU102 4,512,963 347,086 13.00 1 hrs 51 mins
7 RTX A5000
GA102GL [RTX A5000]
Nvidia GA102GL 4,359,657 343,199 12.70 1 hrs 53 mins
8 GeForce RTX 3070 Lite Hash Rate
GA104 [GeForce RTX 3070 Lite Hash Rate]
Nvidia GA104 4,056,214 334,096 12.14 1 hrs 59 mins
9 GeForce RTX 3070
GA104 [GeForce RTX 3070]
Nvidia GA104 4,045,998 333,524 12.13 1 hrs 59 mins
10 GeForce RTX 3060 Ti Lite Hash Rate
GA104 [GeForce RTX 3060 Ti Lite Hash Rate]
Nvidia GA104 3,323,692 314,083 10.58 2 hrs 16 mins
11 GeForce RTX 3080 Mobile / Max-Q 8GB/16GB
GA104M [GeForce RTX 3080 Mobile / Max-Q 8GB/16GB]
Nvidia GA104M 2,570,320 280,712 9.16 2 hrs 37 mins
12 GeForce GTX 1080 Ti
GP102 [GeForce GTX 1080 Ti] 11380
Nvidia GP102 2,427,414 282,976 8.58 2 hrs 48 mins
13 GeForce RTX 2060 Super
TU106 [GeForce RTX 2060 SUPER]
Nvidia TU106 2,049,236 268,895 7.62 3 hrs 9 mins
14 GeForce RTX 2070
TU106 [GeForce RTX 2070]
Nvidia TU106 2,030,846 268,822 7.55 3 hrs 11 mins
15 GeForce RTX 3060 Lite Hash Rate
GA106 [GeForce RTX 3060 Lite Hash Rate]
Nvidia GA106 1,966,188 263,627 7.46 3 hrs 13 mins
16 GeForce GTX 1080
GP104 [GeForce GTX 1080] 8873
Nvidia GP104 1,363,254 240,586 5.67 4 hrs 14 mins
17 GeForce GTX 1660 SUPER
TU116 [GeForce GTX 1660 SUPER]
Nvidia TU116 1,052,867 217,423 4.84 4 hrs 57 mins
18 GeForce GTX 1070
GP104 [GeForce GTX 1070] 6463
Nvidia GP104 1,037,395 215,471 4.81 4 hrs 59 mins
19 Tesla M40
GM200GL [Tesla M40] 6844
Nvidia GM200GL 1,030,119 212,341 4.85 4 hrs 57 mins
20 GeForce RTX 2060
TU104 [GeForce RTX 2060]
Nvidia TU104 709,963 110,727 6.41 3 hrs 45 mins
21 GeForce GTX 1060 6GB
GP106 [GeForce GTX 1060 6GB] 4372
Nvidia GP106 612,654 179,778 3.41 7 hrs 3 mins
22 GeForce GTX 980
GM204 [GeForce GTX 980] 4612
Nvidia GM204 549,356 173,160 3.17 7 hrs 34 mins
23 GeForce GTX 970
GM204 [GeForce GTX 970] 3494
Nvidia GM204 474,149 166,791 2.84 8 hrs 27 mins
24 GeForce GTX 1650
TU117 [GeForce GTX 1650]
Nvidia TU117 303,781 153,943 1.97 12 hrs 10 mins
25 Quadro K1200
GM107GL [Quadro K1200]
Nvidia GM107GL 47,489 79,305 0.60 40 hrs 5 mins