PROJECT #17705 RESEARCH FOR PARKINSONS
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

The 17000-17710 project series contains simulations of the serotonin transporter, the protein responsible for terminating neurotransmission in neurons.

The neurotransmitter serotonin regulates various functions in the body such as mood, behavior, appettite, and sleep, and is a major drug targets for antidepressants.

Malfunctions in the serotonin transporter have been assoicated with mental disorders including depression and Parkinson's.

Our goal in performing these simulations is to understand how mutations affect the structure and dynamics of the serotonin transporter and provide insights to treat psychatric disorders assoicated with these mutations..

PROJECT INFO

Manager(s): Matthew Chan

Institution: University of Illinois at Urbana-Champaign

PROJECT WORK UNIT SUMMARY

Atoms: 65,675

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Tuesday, 31 January 2023 00:15:01

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	5,893,791	155,468	37.91	0 ^hrs 38 ^mins
2	GeForce RTX 3080 10GB / 20GB GA102 [GeForce RTX 3080 10GB / 20GB]	Nvidia	GA102	4,726,104	144,586	32.69	0 ^hrs 44 ^mins
3	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	4,226,664	139,300	30.34	0 ^hrs 47 ^mins
4	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	3,496,228	131,295	26.63	0 ^hrs 54 ^mins
5	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	3,281,110	128,859	25.46	0 ^hrs 57 ^mins
6	Radeon RX 6800/6800 XT / 6900 XT Navi 21 [Radeon RX 6800/6800 XT / 6900 XT]	AMD	Navi 21	2,938,110	124,321	23.63	1 ^hrs 1 ^mins
7	GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068	Nvidia	TU104	2,934,614	125,746	23.34	1 ^hrs 2 ^mins
8	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,825,321	122,168	23.13	1 ^hrs 2 ^mins
9	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	2,598,019	118,805	21.87	1 ^hrs 6 ^mins
10	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,365,516	115,488	20.48	1 ^hrs 10 ^mins
11	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	2,270,380	113,898	19.93	1 ^hrs 12 ^mins
12	GeForce RTX 2070 TU106 [GeForce RTX 2070] M 6497	Nvidia	TU106	1,830,912	106,114	17.25	1 ^hrs 23 ^mins
13	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	1,762,428	104,918	16.80	1 ^hrs 26 ^mins
14	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,582,883	101,262	15.63	2 ^hrs 32 ^mins
15	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	1,502,471	99,013	15.17	2 ^hrs 35 ^mins
16	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	1,307,172	94,717	13.80	2 ^hrs 44 ^mins
17	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,106,381	89,627	12.34	2 ^hrs 57 ^mins
18	GeForce RTX 2060 TU106 [Geforce RTX 2060]	Nvidia	TU106	1,034,382	86,493	11.96	2 ^hrs 0 ^mins
19	GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632	Nvidia	GM200	921,585	81,158	11.36	2 ^hrs 7 ^mins
20	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	919,333	84,406	10.89	2 ^hrs 12 ^mins
21	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	917,692	82,561	11.12	2 ^hrs 10 ^mins
22	Radeon RX 5600 OEM/5600 XT/5700/5700 XT Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT]	AMD	Navi 10	855,813	81,547	10.49	2 ^hrs 17 ^mins
23	Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64]	AMD	Vega 10 XL/XT	811,548	70,340	11.54	2 ^hrs 5 ^mins
24	GeForce GTX 980 GM204 [GeForce GTX 980] 4612	Nvidia	GM204	666,775	76,186	8.75	3 ^hrs 45 ^mins
25	GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372	Nvidia	GP106	639,583	74,944	8.53	3 ^hrs 49 ^mins
26	GeForce GTX 1070 GP104 [GeForce GTX 1070]	Nvidia	GP104	638,172	74,775	8.53	3 ^hrs 49 ^mins
27	GeForce GTX 970 GM204 [GeForce GTX 970] 3494	Nvidia	GM204	587,945	73,002	8.05	3 ^hrs 59 ^mins
28	Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590]	AMD	Ellesmere XT	447,008	66,444	6.73	4 ^hrs 34 ^mins
29	GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q]	Nvidia	TU117M	441,544	66,677	6.62	4 ^hrs 37 ^mins
30	GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935	Nvidia	GP106	440,940	66,097	6.67	4 ^hrs 36 ^mins
31	GeForce GTX 1650 TU116 [GeForce GTX 1650] 2984	Nvidia	TU116	439,033	65,997	6.65	4 ^hrs 36 ^mins
32	P106-100 GP106 [P106-100]	Nvidia	GP106	403,097	64,180	6.28	4 ^hrs 49 ^mins
33	Radeon R9 200/300X Series Hawaii [Radeon R9 200/300X Series]	AMD	Hawaii	314,307	58,852	5.34	4 ^hrs 30 ^mins
34	P106-090 GP106 [P106-090]	Nvidia	GP106	236,315	53,857	4.39	5 ^hrs 28 ^mins
35	GeForce GTX 680 GK104 [GeForce GTX 680] 3250	Nvidia	GK104	189,951	50,089	3.79	6 ^hrs 20 ^mins
36	Quadro P1000 GP107GL [Quadro P1000]	Nvidia	GP107GL	186,202	49,881	3.73	6 ^hrs 26 ^mins
37	Radeon R9 200/300 Series Tonga [Radeon R9 200/300 Series]	AMD	Tonga	179,369	48,899	3.67	7 ^hrs 33 ^mins
38	Quadro P620 GP107GL [Quadro P620]	Nvidia	GP107GL	133,854	44,623	3.00	8 ^hrs 0 ^mins
39	GeForce GTX 750 Ti GM107 [GeForce GTX 750 Ti] 1389	Nvidia	GM107	128,656	43,960	2.93	8 ^hrs 12 ^mins
40	Radeon HD 7800 Pitcairn [Radeon HD 7800]	AMD	Pitcairn	120,070	42,966	2.79	9 ^hrs 35 ^mins
41	Quadro K2200 GM107GL [Quadro K2200]	Nvidia	GM107GL	114,609	42,439	2.70	9 ^hrs 53 ^mins
42	GeForce GT 1030 GP108 [GeForce GT 1030] 1127	Nvidia	GP108	95,281	39,843	2.39	10 ^hrs 2 ^mins
43	Quadro K1200 GM107GL [Quadro K1200]	Nvidia	GM107GL	77,809	37,245	2.09	11 ^hrs 29 ^mins
44	Quadro K620 GM107GL [Quadro K620]	Nvidia	GM107GL	54,486	33,006	1.65	15 ^hrs 32 ^mins
45	GeForce MX250 GP108M [GeForce MX250]	Nvidia	GP108M	44,588	27,187	1.64	15 ^hrs 38 ^mins
46	Radeon APU A4-6000 R2 Mullins [Radeon APU A4-6000 R2]	AMD	Mullins	2,956	13,350	0.22	108 ^hrs 23 ^mins
47	GeForce GTX 1650 SUPER TU116 [GeForce GTX 1650 SUPER]	Nvidia	TU116	645	13,350	0.05	497 ^hrs 45 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA