PROJECT #17709 RESEARCH FOR PARKINSONS
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

The 17000-17710 project series contains simulations of the serotonin transporter, the protein responsible for terminating neurotransmission in neurons.

The neurotransmitter serotonin regulates various functions in the body such as mood, behavior, appettite, and sleep, and is a major drug targets for antidepressants.

Malfunctions in the serotonin transporter have been assoicated with mental disorders including depression and Parkinson's.

Our goal in performing these simulations is to understand how mutations affect the structure and dynamics of the serotonin transporter and provide insights to treat psychatric disorders assoicated with these mutations..

PROJECT INFO

Manager(s): Matthew Chan

Institution: University of Illinois at Urbana-Champaign

PROJECT WORK UNIT SUMMARY

Atoms: 65,661

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 03 October 2022 12:16:34

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	6,103,245	158,014	38.62	1 ^hrs 37 ^mins
2	GeForce RTX 3080 10GB / 20GB GA102 [GeForce RTX 3080 10GB / 20GB]	Nvidia	GA102	4,345,085	137,639	31.57	1 ^hrs 46 ^mins
3	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	4,229,704	139,778	30.26	1 ^hrs 48 ^mins
4	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	3,167,292	121,897	25.98	1 ^hrs 55 ^mins
5	GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068	Nvidia	TU104	3,026,632	125,494	24.12	1 ^hrs 60 ^mins
6	Radeon RX 6800/6800 XT / 6900 XT Navi 21 [Radeon RX 6800/6800 XT / 6900 XT]	AMD	Navi 21	2,928,761	124,479	23.53	1 ^hrs 1 ^mins
7	GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER]	Nvidia	TU104	2,890,809	123,160	23.47	1 ^hrs 1 ^mins
8	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	2,549,515	118,277	21.56	1 ^hrs 7 ^mins
9	GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380	Nvidia	GP102	2,384,884	116,143	20.53	1 ^hrs 10 ^mins
10	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	2,173,435	110,450	19.68	1 ^hrs 13 ^mins
11	GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A] M 7465	Nvidia	TU106	2,163,779	112,034	19.31	1 ^hrs 15 ^mins
12	GeForce RTX 2070 TU106 [GeForce RTX 2070] M 6497	Nvidia	TU106	1,806,861	105,895	17.06	1 ^hrs 24 ^mins
13	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	1,749,307	104,493	16.74	1 ^hrs 26 ^mins
14	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	1,534,033	99,906	15.35	2 ^hrs 34 ^mins
15	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,518,255	99,687	15.23	2 ^hrs 35 ^mins
16	Quadro RTX 4000 TU104GL [Quadro RTX 4000]	Nvidia	TU104GL	1,452,437	98,345	14.77	2 ^hrs 38 ^mins
17	GeForce GTX 1070 Ti GP104 [GeForce GTX 1070 Ti] 8186	Nvidia	GP104	1,283,626	94,369	13.60	2 ^hrs 46 ^mins
18	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,129,379	90,484	12.48	2 ^hrs 55 ^mins
19	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,067,916	88,987	12.00	2 ^hrs 60 ^mins
20	Radeon VII Vega 20 [Radeon VII] 13,284	AMD	Vega 20	1,021,295	85,395	11.96	2 ^hrs 0 ^mins
21	GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632	Nvidia	GM200	997,286	86,884	11.48	2 ^hrs 5 ^mins
22	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	957,618	85,893	11.15	2 ^hrs 9 ^mins
23	GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti]	Nvidia	TU116	942,262	85,065	11.08	2 ^hrs 10 ^mins
24	Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64]	AMD	Vega 10 XL/XT	929,895	84,753	10.97	2 ^hrs 11 ^mins
25	Radeon RX 5600 OEM/5600 XT/5700/5700 XT Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT]	AMD	Navi 10	883,620	83,454	10.59	2 ^hrs 16 ^mins
26	P104-100 GP104 [P104-100]	Nvidia	GP104	583,487	72,535	8.04	3 ^hrs 59 ^mins
27	GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935	Nvidia	GP106	546,467	70,961	7.70	3 ^hrs 7 ^mins
28	GeForce GTX 970 GM204 [GeForce GTX 970] 3494	Nvidia	GM204	545,444	71,187	7.66	3 ^hrs 8 ^mins
29	Radeon RX 5500/5500M / Pro 5500M Navi 14 [Radeon RX 5500/5500M / Pro 5500M]	AMD	Navi 14	465,579	67,355	6.91	3 ^hrs 28 ^mins
30	GeForce GTX 1650 TU116 [GeForce GTX 1650] 2984	Nvidia	TU116	464,135	67,483	6.88	3 ^hrs 29 ^mins
31	GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q]	Nvidia	TU117M	462,969	67,541	6.85	4 ^hrs 30 ^mins
32	Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590]	AMD	Ellesmere XT	424,905	64,891	6.55	4 ^hrs 40 ^mins
33	P106-100 GP106 [P106-100]	Nvidia	GP106	403,117	64,384	6.26	4 ^hrs 50 ^mins
34	Radeon R9 200/300X Series Hawaii [Radeon R9 200/300X Series]	AMD	Hawaii	311,733	58,810	5.30	5 ^hrs 32 ^mins
35	GeForce GTX 960 GM206 [GeForce GTX 960] 2308	Nvidia	GM206	260,771	55,751	4.68	5 ^hrs 8 ^mins
36	P106-090 GP106 [P106-090]	Nvidia	GP106	215,752	52,042	4.15	6 ^hrs 47 ^mins
37	Radeon R9 280/HD 7900/8950 Tahiti PRO [Radeon R9 280/HD 7900/8950]	AMD	Tahiti PRO	198,788	51,019	3.90	6 ^hrs 10 ^mins
38	Radeon R9 200/300 Series Tonga [Radeon R9 200/300 Series]	AMD	Tonga	181,578	49,299	3.68	7 ^hrs 31 ^mins
39	Quadro P620 GP107GL [Quadro P620]	Nvidia	GP107GL	134,576	44,712	3.01	8 ^hrs 58 ^mins
40	GeForce GTX 750 Ti GM107 [GeForce GTX 750 Ti] 1389	Nvidia	GM107	131,289	44,092	2.98	8 ^hrs 4 ^mins
41	Quadro P1000 GP107GL [Quadro P1000]	Nvidia	GP107GL	122,519	43,316	2.83	8 ^hrs 29 ^mins
42	Radeon HD 7800 Pitcairn [Radeon HD 7800]	AMD	Pitcairn	120,724	43,051	2.80	9 ^hrs 34 ^mins
43	Quadro K2200 GM107GL [Quadro K2200]	Nvidia	GM107GL	116,195	42,623	2.73	9 ^hrs 48 ^mins
44	GeForce GT 1030 GP108 [GeForce GT 1030] 1127	Nvidia	GP108	99,024	40,380	2.45	10 ^hrs 47 ^mins
45	Quadro K1200 GM107GL [Quadro K1200]	Nvidia	GM107GL	78,127	37,230	2.10	11 ^hrs 26 ^mins
46	Quadro K620 GM107GL [Quadro K620]	Nvidia	GM107GL	54,731	33,175	1.65	15 ^hrs 33 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA