Folding project #12707, CANNABINOID research

Research section Research projects and references

Project #12707 overview

Project Summary AI Beta

This project relates to cannabinoid receptors, which control things like pain, appetite, and learning. By testing different drugs on these receptors, we can learn how they work and if a drug is safe and effective for treating conditions.

Automated summary; simplified and may not be fully accurate.

Project team

Manager(s): Michael Chen
Institution: University of Illinois Urbana-Champaign

Work unit

Atoms: 91,174
Core: 0x27
Status: Public

Source material

Official Project Description

Cannabinoid G Protein Coupled Receptors Improper signaling through Cannabinoid receptors is linked to drug addiction, pain perception, appetite regulation and learning.

Simulation of these proteins with different small molecules helps us to understand their function and the selectivity/efficacy of these potential drugs to the nervous system.

Reading reference

Related Terms Glossary AI Beta

Automated high-level definitions; simplified and may not be fully accurate.

Cannabinoid

A class of psychoactive compounds found in cannabis plants.

Scientific: BiotechnologyPharmacology / Neuropharmacology

Cannabinoids are a group of chemicals derived from the cannabis plant. They interact with the body's endocannabinoid system, which plays a role in regulating various functions like mood, appetite, sleep, and pain perception. Different cannabinoids have varying effects, some producing psychoactive experiences (like THC) while others may offer therapeutic benefits (like CBD).

G Protein Coupled Receptors

Receptors that activate G proteins upon ligand binding.

Scientific: BiotechnologyPharmacology / Cell Signaling

G protein-coupled receptors (GPCRs) are a large family of cell surface receptors involved in transmitting signals within cells. When a molecule called a ligand binds to a GPCR, it triggers a cascade of events inside the cell by activating a protein called a G protein. This activation leads to various cellular responses, including changes in gene expression, metabolism, and behavior.

GPU PPD Averages

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 5090 GB202 [GeForce RTX 5090]	Nvidia	GB202	28,588,695	51,500	555.12	0 ^hrs 3 ^mins
2	GeForce RTX 4090 AD102 [GeForce RTX 4090]	Nvidia	AD102	21,794,397	282,340	77.19	0 ^hrs 19 ^mins
3	GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti]	Nvidia	GA104	16,668,364	51,500	323.66	0 ^hrs 4 ^mins
4	GeForce RTX 4080 SUPER AD103 [GeForce RTX 4080 SUPER]	Nvidia	AD103	16,028,318	110,570	144.96	0 ^hrs 10 ^mins
5	GeForce RTX 5080 GB203 [GeForce RTX 5080]	Nvidia	GB203	15,725,120	51,500	305.34	0 ^hrs 5 ^mins
6	GeForce RTX 4080 AD103 [GeForce RTX 4080]	Nvidia	AD103	14,992,296	149,823	100.07	0 ^hrs 14 ^mins
7	GeForce RTX 5070 Ti GB203 [GeForce RTX 5070 Ti]	Nvidia	GB203	14,417,363	190,553	75.66	0 ^hrs 19 ^mins
8	GeForce RTX 4070 Ti AD104 [GeForce RTX 4070 Ti]	Nvidia	AD104	11,825,677	303,947	38.91	0 ^hrs 37 ^mins
9	GeForce RTX 4070 SUPER AD104 [GeForce RTX 4070 SUPER]	Nvidia	AD104	11,312,034	189,404	59.72	0 ^hrs 24 ^mins
10	GeForce RTX 4070 Ti SUPER AD103 [GeForce RTX 4070 Ti SUPER]	Nvidia	AD103	10,872,768	51,500	211.12	0 ^hrs 7 ^mins
11	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	10,232,009	51,500	198.68	0 ^hrs 7 ^mins
12	GeForce RTX 5070 GB205 [GeForce RTX 5070]	Nvidia	GB205	10,057,733	51,500	195.30	0 ^hrs 7 ^mins
13	GeForce RTX 3080 12GB GA102 [GeForce RTX 3080 12GB]	Nvidia	GA102	9,353,588	51,500	181.62	0 ^hrs 8 ^mins
14	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	8,966,918	51,500	174.11	0 ^hrs 8 ^mins
15	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	8,452,835	244,334	34.60	0 ^hrs 42 ^mins
16	GeForce RTX 4060 Ti AD104 [GeForce RTX 4060 Ti]	Nvidia	AD104	8,358,687	51,500	162.30	0 ^hrs 9 ^mins
17	GeForce RTX 3080 GA102 [GeForce RTX 3080]	Nvidia	GA102	7,020,518	187,979	37.35	0 ^hrs 39 ^mins
18	Radeon RX 7900XT/XTX/GRE Navi 31 [Radeon RX 7900XT/XTX/GRE]	AMD	Navi 31	6,829,486	61,517	111.02	0 ^hrs 13 ^mins
19	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	6,774,216	51,500	131.54	0 ^hrs 11 ^mins

20	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	6,140,330	51,500	119.23	0 ^hrs 12 ^mins
21	GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448	Nvidia	TU102	6,043,686	51,500	117.35	0 ^hrs 12 ^mins
22	TITAN V GV100 [TITAN V] M 12288	Nvidia	GV100	5,860,356	51,500	113.79	0 ^hrs 13 ^mins
23	GeForce RTX 4060 Ti AD106 [GeForce RTX 4060 Ti]	Nvidia	AD106	5,717,703	226,926	25.20	0 ^hrs 57 ^mins
24	GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate]	Nvidia	GA104	5,633,950	155,647	36.20	0 ^hrs 40 ^mins
25	GeForce RTX 4070 AD104 [GeForce RTX 4070]	Nvidia	AD104	5,415,588	148,585	36.45	0 ^hrs 40 ^mins
26	GeForce RTX 4070 Max-Q / Mobile AD106M [GeForce RTX 4070 Max-Q / Mobile]	Nvidia	AD106M	5,263,874	51,500	102.21	0 ^hrs 14 ^mins
27	Radeon RX 9070(XT) Navi 48 [Radeon RX 9070(XT)]	AMD	Navi 48	5,025,074	142,637	35.23	0 ^hrs 41 ^mins
28	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	4,639,303	173,542	26.73	0 ^hrs 54 ^mins
29	Radeon RX 6800(XT)/6900XT Navi 21 [Radeon RX 6800(XT)/6900XT]	AMD	Navi 21	4,080,490	159,620	25.56	0 ^hrs 56 ^mins
30	Radeon RX 6950 XT Navi 21 [Radeon RX 6950 XT]	AMD	Navi 21	4,067,553	51,500	78.98	0 ^hrs 18 ^mins
31	GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate]	Nvidia	GA104	3,803,748	71,939	52.87	0 ^hrs 27 ^mins
32	GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218	Nvidia	TU104	3,675,039	179,668	20.45	1 ^hrs 10 ^mins
33	GeForce RTX 4060 AD107 [GeForce RTX 4060]	Nvidia	AD107	3,260,793	55,185	59.09	0 ^hrs 24 ^mins
34	GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate]	Nvidia	GA106	2,806,556	136,526	20.56	1 ^hrs 10 ^mins
35	Quadro RTX 4000 TU104GL [Quadro RTX 4000]	Nvidia	TU104GL	2,717,383	51,500	52.76	0 ^hrs 27 ^mins
36	GeForce RTX 2070 TU106 [GeForce RTX 2070]	Nvidia	TU106	2,618,083	216,935	12.07	1 ^hrs 59 ^mins
37	GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER]	Nvidia	TU106	2,617,008	209,713	12.48	1 ^hrs 55 ^mins
38	GeForce RTX 2060 TU106 [Geforce RTX 2060]	Nvidia	TU106	2,604,377	123,700	21.05	1 ^hrs 8 ^mins
39	GeForce RTX 3060 GA104 [GeForce RTX 3060]	Nvidia	GA104	2,591,846	51,500	50.33	0 ^hrs 29 ^mins

40	GeForce RTX 4060 Max-Q / Mobile AD107M [GeForce RTX 4060 Max-Q / Mobile]	Nvidia	AD107M	2,088,123	51,500	40.55	0 ^hrs 36 ^mins
41	RTX PRO 6000 Blackwell Max-Q Workstation Edition GB202GL [RTX PRO 6000 Blackwell Max-Q Workstation Edition]	Nvidia	GB202GL	2,050,272	51,500	39.81	0 ^hrs 36 ^mins
42	GeForce RTX 5060 Ti GB206 [GeForce RTX 5060 Ti]	Nvidia	GB206	2,035,724	51,500	39.53	0 ^hrs 36 ^mins
43	GeForce GTX 1660 TU116 [GeForce GTX 1660]	Nvidia	TU116	1,919,495	51,500	37.27	0 ^hrs 39 ^mins
44	GeForce GTX 1660 Ti TU116 [GeForce GTX 1660 Ti]	Nvidia	TU116	1,888,771	51,500	36.68	0 ^hrs 39 ^mins
45	Radeon RX 6700(XT)/6800M Navi 22 XT-XL [Radeon RX 6700(XT)/6800M]	AMD	Navi 22 XT-XL	1,872,399	51,500	36.36	0 ^hrs 40 ^mins
46	GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873	Nvidia	GP104	1,770,366	192,092	9.22	2 ^hrs 36 ^mins
47	GeForce RTX 2060 Mobile / Max-Q TU106M [GeForce RTX 2060 Mobile / Max-Q]	Nvidia	TU106M	1,668,743	51,500	32.40	0 ^hrs 44 ^mins
48	RTX A2000 GA106 [RTX A2000]	Nvidia	GA106	1,620,404	51,500	31.46	0 ^hrs 46 ^mins
49	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,525,941	51,500	29.63	0 ^hrs 49 ^mins
50	GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632	Nvidia	GM200	1,525,927	181,975	8.39	2 ^hrs 52 ^mins
51	GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463	Nvidia	GP104	1,387,699	176,467	7.86	3 ^hrs 3 ^mins
52	P104-100 GP104 [P104-100]	Nvidia	GP104	1,350,301	51,500	26.22	0 ^hrs 55 ^mins
53	RTX A1000 GA107GL [RTX A1000]	Nvidia	GA107GL	1,207,305	51,500	23.44	1 ^hrs 1 ^mins
54	GeForce RTX 3070 Mobile / Max-Q GA104M [GeForce RTX 3070 Mobile / Max-Q]	Nvidia	GA104M	1,167,570	51,500	22.67	1 ^hrs 4 ^mins
55	GeForce GTX 1070 Mobile GP104BM [GeForce GTX 1070 Mobile] 6463	Nvidia	GP104BM	1,165,362	51,500	22.63	1 ^hrs 4 ^mins
56	Tesla P4 GP104GL [Tesla P4] 5704	Nvidia	GP104GL	933,553	151,389	6.17	3 ^hrs 54 ^mins
57	GeForce RTX 3050 6GB GA107 [GeForce RTX 3050 6GB]	Nvidia	GA107	843,049	51,500	16.37	1 ^hrs 28 ^mins
58	R9 Fury X/NANO Fiji XT [R9 Fury X/NANO]	AMD	Fiji XT	540,912	51,500	10.50	2 ^hrs 17 ^mins
59	Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64]	AMD	Vega 10 XL/XT	465,385	51,500	9.04	2 ^hrs 39 ^mins

60	GeForce GTX 1650 TU117 [GeForce GTX 1650]	Nvidia	TU117	447,908	51,500	8.70	2 ^hrs 46 ^mins
61	Radeon 880M/890M Strix Point [Radeon 880M/890M]	AMD	Strix Point	424,456	51,500	8.24	2 ^hrs 55 ^mins
62	GeForce GTX 1650 TU106 [GeForce GTX 1650]	Nvidia	TU106	247,579	51,500	4.81	4 ^hrs 60 ^mins
63	RX 5500(M)/Pro 5500M Navi 14 [RX 5500(M)/Pro 5500M]	AMD	Navi 14	146,973	51,500	2.85	8 ^hrs 25 ^mins

Research: CANNABINOID Folding Project #12707

Project Summary AI Beta

Project team

Work unit

Official Project Description

Hardware Performance for Project 12707

GPU PPD Averages

Research: CANNABINOID Folding Project #12707

Project Summary AI Beta

Project team

Work unit

Related projects

GPU PPD Averages