PROJECT #18500 RESEARCH FOR PARKINSONS
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
Project 18500 is running wild-type Transmembrane Protein 175 (TMEM175).
Transmembrane Protein 175 (TMEM175) is a protein in the lysosomal membrane that functions as a "channel" for potassium ions to move between the open space in the cell (the cytoplasm) and the space within the lysosome (the lysosomal lumen).
TMEM175 is thought to play an important role in autophagy as a lysosomal protein, but its exact function in this process is not yet clear.
Nevertheless, dysfunction of TMEM175 is implicated in the development of Parkinson’s.
We know this because several mutational variants of TMEM175 have been identified in Parkinson’s patients, and experiments have shown that mice with these variants have some of the molecular and behavioral hallmarks of Parkinson’s.
An understanding of the fundamental mechanisms of TMEM175 will lead to new ways to discover drugs or therapeutic interventions to treat, prevent, or potentially even reverse Parkinson’s Disease..
PROJECT INFO
Manager(s): Viktor Belay
Institution: Memorial Sloan Kettering Cancer Center
Project URL: viktor.belay@choderalab.org
PROJECT WORK UNIT SUMMARY
Atoms: 151,920
Core: OPENMM_22
Status: Public
PROJECT FOLDING PPD AVERAGES BY GPU
PPDDB data as of Monday, 27 June 2022 11:45:17
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
---|---|---|---|---|---|---|---|
1 | GeForce RTX 3090 Ti GA102 [GeForce RTX 3090 Ti] |
Nvidia | GA102 | 9,990,835 | 606,533 | 16.47 | 1 hrs 27 mins |
2 | GeForce RTX 3090 GA102 [GeForce RTX 3090] |
Nvidia | GA102 | 9,084,115 | 583,628 | 15.56 | 2 hrs 33 mins |
3 | GeForce RTX 3080 GA102 [GeForce RTX 3080] |
Nvidia | GA102 | 8,233,191 | 567,745 | 14.50 | 2 hrs 39 mins |
4 | GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti] |
Nvidia | GA102 | 7,895,687 | 556,069 | 14.20 | 2 hrs 41 mins |
5 | GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate] |
Nvidia | GA102 | 6,700,229 | 520,685 | 12.87 | 2 hrs 52 mins |
6 | GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448 |
Nvidia | TU102 | 5,399,124 | 493,067 | 10.95 | 2 hrs 12 mins |
7 | GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate] |
Nvidia | GA104 | 4,756,371 | 468,972 | 10.14 | 2 hrs 22 mins |
8 | GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti] |
Nvidia | GA104 | 4,715,654 | 468,707 | 10.06 | 2 hrs 23 mins |
9 | GeForce RTX 3070 GA104 [GeForce RTX 3070] |
Nvidia | GA104 | 4,275,927 | 451,039 | 9.48 | 3 hrs 32 mins |
10 | GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448 |
Nvidia | TU102 | 3,946,777 | 371,162 | 10.63 | 2 hrs 15 mins |
11 | GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER] |
Nvidia | TU104 | 3,893,984 | 442,418 | 8.80 | 3 hrs 44 mins |
12 | GeForce RTX 3070 Mobile / Max-Q GA104M [GeForce RTX 3070 Mobile / Max-Q] |
Nvidia | GA104M | 3,514,758 | 429,618 | 8.18 | 3 hrs 56 mins |
13 | GeForce RTX 2070 SUPER TU104 [GeForce RTX 2070 SUPER] 8218 |
Nvidia | TU104 | 3,488,929 | 428,084 | 8.15 | 3 hrs 57 mins |
14 | GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate] |
Nvidia | GA104 | 3,456,045 | 424,804 | 8.14 | 3 hrs 57 mins |
15 | GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380 |
Nvidia | GP102 | 2,613,134 | 394,658 | 6.62 | 4 hrs 37 mins |
16 | GeForce RTX 3060 Lite Hash Rate GA106 [GeForce RTX 3060 Lite Hash Rate] |
Nvidia | GA106 | 2,472,520 | 380,878 | 6.49 | 4 hrs 42 mins |
17 | GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER] |
Nvidia | TU106 | 2,356,053 | 376,991 | 6.25 | 4 hrs 50 mins |
18 | GeForce RTX 2060 TU106 [Geforce RTX 2060] |
Nvidia | TU106 | 2,287,946 | 367,263 | 6.23 | 4 hrs 51 mins |
19 | Quadro RTX 4000 TU104GL [Quadro RTX 4000] |
Nvidia | TU104GL | 2,072,027 | 359,411 | 5.77 | 4 hrs 10 mins |
20 | GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q] |
Nvidia | GA106M | 1,967,765 | 366,430 | 5.37 | 4 hrs 28 mins |
21 | GeForce RTX 2070 TU106 [GeForce RTX 2070] |
Nvidia | TU106 | 1,739,808 | 329,111 | 5.29 | 5 hrs 32 mins |
22 | GeForce RTX 2060 TU104 [GeForce RTX 2060] |
Nvidia | TU104 | 1,578,178 | 330,971 | 4.77 | 5 hrs 2 mins |
23 | GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873 |
Nvidia | GP104 | 1,509,202 | 331,221 | 4.56 | 5 hrs 16 mins |
24 | GeForce GTX 980 Ti GM200 [GeForce GTX 980 Ti] 5632 |
Nvidia | GM200 | 1,446,275 | 319,392 | 4.53 | 5 hrs 18 mins |
25 | Geforce RTX 3050 GA106 [Geforce RTX 3050] |
Nvidia | GA106 | 1,385,645 | 325,839 | 4.25 | 6 hrs 39 mins |
26 | GeForce RTX 2060 Mobile / Max-Q TU106M [GeForce RTX 2060 Mobile / Max-Q] |
Nvidia | TU106M | 1,307,843 | 308,472 | 4.24 | 6 hrs 40 mins |
27 | GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER] |
Nvidia | TU116 | 1,272,299 | 311,693 | 4.08 | 6 hrs 53 mins |
28 | GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463 |
Nvidia | GP104 | 1,212,645 | 305,345 | 3.97 | 6 hrs 3 mins |
29 | Tesla M40 GM200GL [Tesla M40] 6844 |
Nvidia | GM200GL | 1,126,831 | 293,070 | 3.84 | 6 hrs 15 mins |
30 | P104-100 GP104 [P104-100] |
Nvidia | GP104 | 1,076,818 | 290,046 | 3.71 | 6 hrs 28 mins |
31 | GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372 |
Nvidia | GP106 | 820,154 | 265,546 | 3.09 | 8 hrs 46 mins |
32 | GeForce GTX 1650 TU117 [GeForce GTX 1650] |
Nvidia | TU117 | 599,866 | 238,272 | 2.52 | 10 hrs 32 mins |
33 | GeForce GTX 1660 TU116 [GeForce GTX 1660] |
Nvidia | TU116 | 536,274 | 257,254 | 2.08 | 12 hrs 31 mins |
34 | GeForce GTX 980 GM204 [GeForce GTX 980] 4612 |
Nvidia | GM204 | 472,959 | 222,651 | 2.12 | 11 hrs 18 mins |
35 | Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590] |
AMD | Ellesmere XT | 347,483 | 166,768 | 2.08 | 12 hrs 31 mins |
36 | Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64] |
AMD | Vega 10 XL/XT | 259,538 | 137,227 | 1.89 | 13 hrs 41 mins |
37 | GeForce GTX 950 GM206 [GeForce GTX 950] 1572 |
Nvidia | GM206 | 258,612 | 179,847 | 1.44 | 17 hrs 41 mins |
38 | GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q] |
Nvidia | TU117M | 236,964 | 169,054 | 1.40 | 17 hrs 7 mins |
39 | GeForce GTX 750 Ti GM107 [GeForce GTX 750 Ti] 1389 |
Nvidia | GM107 | 142,755 | 147,616 | 0.97 | 25 hrs 49 mins |
40 | Quadro K2200 GM107GL [Quadro K2200] |
Nvidia | GM107GL | 75,150 | 138,448 | 0.54 | 44 hrs 13 mins |
41 | Quadro K620 GM107GL [Quadro K620] |
Nvidia | GM107GL | 39,845 | 105,852 | 0.38 | 64 hrs 45 mins |
42 | GeForce GT 710 GK208B [GeForce GT 710] 366 |
Nvidia | GK208B | 7,126 | 77,795 | 0.09 | 262 hrs 1 mins |
PROJECT FOLDING PPD AVERAGES BY CPU BETA
PPDDB data as of Monday, 27 June 2022 11:45:17
Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
---|
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