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Research: LOGP Folding Project #18466

Project #18466 overview

Project Summary AI Beta

This project uses computer simulations to predict how well drugs dissolve in water compared to oil. This is important because it helps scientists understand how easily drugs can be absorbed by the body.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Prof. Vincent Voelz
Institution
Temple University

Work unit

Atoms
14,398
Core
0xa8
Status
Public
Source material

Official Project Description

A key challenge in computational drug discovery is developing and testing methods to predict experimental partition coefficients for the relative solubility of organic molecules in aquoeus vs/ non-polar media.

The logarithm of the partition coeffient, logP, is an important predictor of lipophilicity, which dictates the bioavailability of drugs.

These CPU projects are expanded-ensemble (EE) simulations designed to predict water/toluene partition coefficients of small-molecule drugs as part of the recent SAMPL9 logP challenge.

Performance data

Hardware Performance for Project 18466

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 21:51:12

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 13TH GEN CORE I9-13900KS 32 28,004 896,128 Intel
2 RYZEN 9 7900X 12-CORE 24 25,633 615,192 AMD
3 RYZEN 9 7900 12-CORE 24 24,132 579,168 AMD
4 RYZEN 7 7700X 8-CORE 16 32,339 517,424 AMD
5 RYZEN 9 5950X 16-CORE 32 15,199 486,368 AMD
6 RYZEN 7 5700X 8-CORE 16 23,942 383,072 AMD
7 RYZEN 7 5800X3D 8-CORE 16 20,906 334,496 AMD
8 RYZEN 7 3800X 8-CORE 16 19,353 309,648 AMD
9 CORE I9-10920X CPU @ 3.50GHZ 24 12,221 293,304 Intel
10 RYZEN 7 5800X 8-CORE 16 18,319 293,104 AMD
11 RYZEN 7 5700G 16 17,576 281,216 AMD
12 12TH GEN CORE I5-12600K 16 17,149 274,384 Intel
13 RYZEN 9 3900X 12-CORE 24 11,175 268,200 AMD
14 RYZEN 9 5900X 12-CORE 24 11,023 264,552 AMD
15 CORE I7-10700K CPU @ 3.80GHZ 16 16,459 263,344 Intel
16 12TH GEN CORE I7-12700 20 13,045 260,900 Intel
17 CORE I7-8700 CPU @ 3.20GHZ 12 21,522 258,264 Intel
18 RYZEN 9 3950X 16-CORE 32 6,565 210,080 AMD
19 RYZEN 5 5600X 6-CORE 12 17,382 208,584 AMD
20 RYZEN 5 4500 6-CORE 12 16,161 193,932 AMD
21 RYZEN 7 PRO 4750G 16 11,680 186,880 AMD
22 11TH GEN CORE I9-11900K @ 3.50GHZ 16 11,019 176,304 Intel
23 CORE I7-9700K CPU @ 3.60GHZ 8 21,952 175,616 Intel
24 11TH GEN CORE I5-11400F @ 2.60GHZ 12 14,477 173,724 Intel
25 RYZEN 5 3600 6-CORE 12 13,865 166,380 AMD
26 RYZEN 7 3700X 8-CORE 16 10,286 164,576 AMD
27 RYZEN 3 3100 4-CORE 8 20,266 162,128 AMD
28 RYZEN 5 3500 6-CORE 6 26,957 161,742 AMD
29 CORE I9-9900K CPU @ 3.60GHZ 16 8,633 138,128 Intel
30 CORE I7-5930K CPU @ 3.50GHZ 12 9,993 119,916 Intel
31 CORE I7-7700K CPU @ 4.20GHZ 8 13,935 111,480 Intel
32 RYZEN 7 1700 EIGHT-CORE 16 6,653 106,448 AMD
33 CORE I7-5820K CPU @ 3.30GHZ 12 8,512 102,144 Intel
34 CORE I7-6950X CPU @ 3.00GHZ 20 5,023 100,460 Intel
35 CORE I9-7940X CPU @ 3.10GHZ 28 3,582 100,296 Intel
36 CORE I9-8950HK CPU @ 2.90GHZ 12 7,856 94,272 Intel
37 CORE I7-10700T CPU @ 2.00GHZ 16 5,783 92,528 Intel
38 XEON CPU E5-2670 0 @ 2.60GHZ 32 2,827 90,464 Intel
39 CORE I7-6700T CPU @ 2.80GHZ 8 10,773 86,184 Intel
40 CORE I7-8705G CPU @ 3.10GHZ 8 10,032 80,256 Intel
41 XEON CPU E5-2697 V2 @ 2.70GHZ 24 3,237 77,688 Intel
42 CORE I5-4690 CPU @ 3.50GHZ 4 19,008 76,032 Intel
43 APPLE M1 8 8,430 67,440 Apple
44 CORE I7-4770HQ CPU @ 2.20GHZ 8 8,165 65,320 Intel
45 CORE I7-4770 CPU @ 3.40GHZ 8 7,858 62,864 Intel
46 RYZEN 5 2400G 8 7,362 58,896 AMD
47 CORE I7-3770K CPU @ 3.50GHZ 8 7,275 58,200 Intel
48 XEON CPU L5640 @ 2.27GHZ 24 2,148 51,552 Intel
49 APPLE M1 PRO 10 5,071 50,710 Apple
50 CORE I5-4590 CPU @ 3.30GHZ 4 12,612 50,448 Intel
51 CORE I7-6700K CPU @ 4.00GHZ 8 6,305 50,440 Intel
52 CORE I5-6600K CPU @ 3.50GHZ 4 8,067 32,268 Intel
53 CORE I7-7700HQ CPU @ 2.80GHZ 8 2,647 21,176 Intel
54 CORE I5-10210U CPU @ 1.60GHZ 7 2,902 20,314 Intel
55 CORE I5-3210M CPU @ 2.50GHZ 4 4,161 16,644 Intel
56 RYZEN 5 3500X 6-CORE 6 2,127 12,762 AMD
57 CORE I3-6006U CPU @ 2.00GHZ 4 2,674 10,696 Intel
58 FX-4300 QUAD-CORE 4 799 3,196 AMD