PROJECT #18308 RESEARCH FOR MYOSINS
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

Although structurally similar, myosins actually differ substantially in their properties and distribution in the body.

This project is studying those differences, especially the differences in speed and power.

We are interested in how this might help us understand diseases that result from defects in myosin, including Usher syndrome and, especially, hypertrophic and dilated cardiomyopathies.

We are using this information to understand and design specific theraputics that don't have off-target effects.

Myosin was featured as the PDB Molecule of the Month in June 2001..

PROJECT INFO

Manager(s): Jeff Lotthammer

Institution: Washington University in St. Louis

PROJECT WORK UNIT SUMMARY

Atoms: 151,363

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Monday, 03 October 2022 12:16:29

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Monday, 03 October 2022 12:16:29

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 5950X 16-CORE 32 24,754 792,128 AMD
2 RYZEN 9 3900 12-CORE 24 28,679 688,296 AMD
3 RYZEN 9 5900X 12-CORE 24 27,603 662,472 AMD
4 RYZEN 9 3950X 16-CORE 32 19,942 638,144 AMD
5 RYZEN 7 5800X 8-CORE 16 36,291 580,656 AMD
6 RYZEN 9 3900XT 12-CORE 24 19,990 479,760 AMD
7 11TH GEN CORE I9-11900K @ 3.50GHZ 16 25,045 400,720 Intel
8 RYZEN 7 5700G 16 24,830 397,280 AMD
9 CORE I9-7920X CPU @ 2.90GHZ 24 16,368 392,832 Intel
10 RYZEN 7 3800X 8-CORE 16 23,566 377,056 AMD
11 11TH GEN CORE I7-11700K @ 3.60GHZ 16 23,521 376,336 Intel
12 12TH GEN CORE I7-12700 20 16,594 331,880 Intel
13 12TH GEN CORE I7-12700K 20 16,035 320,700 Intel
14 XEON CPU E5-2650 V2 @ 2.60GHZ 32 9,481 303,392 Intel
15 RYZEN 5 3600 6-CORE 12 19,507 234,084 AMD
16 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,271 222,504 Intel
17 RYZEN 9 5900HS 16 13,466 215,456 AMD
18 RYZEN 7 3700X 8-CORE 16 13,101 209,616 AMD
19 RYZEN 7 PRO 4750G 16 12,008 192,128 AMD
20 RYZEN 5 5600X 6-CORE 12 14,546 174,552 AMD
21 RYZEN 5 1600 SIX-CORE 12 7,562 90,744 AMD
22 XEON CPU E5-2680 0 @ 2.70GHZ 16 5,429 86,864 Intel
23 CORE I7-4790K CPU @ 4.00GHZ 8 10,411 83,288 Intel
24 CORE I9-8950HK CPU @ 2.90GHZ 12 6,404 76,848 Intel
25 CORE I7-6700 CPU @ 3.40GHZ 8 8,125 65,000 Intel
26 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 7,429 59,432 Intel
27 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,028 56,224 Intel
28 CORE I7-3720QM CPU @ 2.60GHZ 8 6,327 50,616 Intel
29 CORE I5-4590 CPU @ 3.30GHZ 4 12,302 49,208 Intel
30 CORE I5-3570 CPU @ 3.40GHZ 4 10,146 40,584 Intel
31 XEON CPU E31245 @ 3.30GHZ 8 4,190 33,520 Intel
32 XEON CPU E5-2620 0 @ 2.00GHZ 12 2,741 32,892 Intel
33 CORE I3-6006U CPU @ 2.00GHZ 4 2,515 10,060 Intel
34 FX-4300 QUAD-CORE 4 731 2,924 AMD