Folding.LAR.Systems Folding.LAR.Systems Folding.LAR.Systems Folding.LAR.Systems
Research section Research projects and references
  1. Projects
  2. Research Project Folding Profile

Research: MYOSINS Folding Project #18304

Project #18304 overview

Project Summary AI Beta

This project studies the different types of myosin proteins found in our bodies. Myosins are crucial for movement, like muscle contractions and transporting things inside cells. The project explores how fast and strong each type is, hoping to learn more about diseases caused by faulty myosins, such as heart conditions.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Jeff Lotthammer
Institution
Washington University in St. Louis

Work unit

Atoms
278,771
Core
GRO_A8
Status
Public
Source material

Official Project Description

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

Although superficially similar, myosins actually differ substantially in their properties and distribution in the body.

This project is studying those differences, especially the differences in speed and power.

We are interested in how this might help us understand diseases that result from defects in myosin, including Usher syndrome and, especially, hypertrophic and dilated cardiomyopathies.

Myosin was featured as the PDB Molecule of the Month in June 2001.

Performance data

Hardware Performance for Project 18304

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 21:52:21

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 12TH GEN CORE I7-12700K 20 37,749 754,980 Intel
2 RYZEN 9 3900 12-CORE 24 30,297 727,128 AMD
3 RYZEN 9 3950X 16-CORE 32 20,903 668,896 AMD
4 RYZEN 7 5800X 8-CORE 16 40,836 653,376 AMD
5 RYZEN 9 5950X 16-CORE 32 16,728 535,296 AMD
6 RYZEN 9 3900XT 12-CORE 24 22,051 529,224 AMD
7 11TH GEN CORE I9-11900K @ 3.50GHZ 16 27,324 437,184 Intel
8 CORE I9-10850K CPU @ 3.60GHZ 20 20,201 404,020 Intel
9 12TH GEN CORE I7-12700 20 18,595 371,900 Intel
10 RYZEN 7 5700G 16 20,131 322,096 AMD
11 RYZEN 7 3800X 8-CORE 16 18,176 290,816 AMD
12 RYZEN 7 3700X 8-CORE 16 17,866 285,856 AMD
13 XEON CPU E5-2680 V3 @ 2.50GHZ 24 10,703 256,872 Intel
14 RYZEN 5 3600 6-CORE 12 20,903 250,836 AMD
15 RYZEN 9 5900HS 16 13,374 213,984 AMD
16 RYZEN 5 5600X 6-CORE 12 17,322 207,864 AMD
17 CORE I9-9900K CPU @ 3.60GHZ 16 12,504 200,064 Intel
18 CORE I7-8700 CPU @ 3.20GHZ 12 14,978 179,736 Intel
19 RYZEN 7 PRO 4750G 16 9,445 151,120 AMD
20 CORE I7-7700K CPU @ 4.20GHZ 8 14,061 112,488 Intel
21 CORE I7-7700 CPU @ 3.60GHZ 8 12,009 96,072 Intel
22 CORE I7-10700T CPU @ 2.00GHZ 16 5,981 95,696 Intel
23 RYZEN 5 1600 SIX-CORE 12 7,957 95,484 AMD
24 CORE I7-4790K CPU @ 4.00GHZ 8 11,082 88,656 Intel
25 CORE I7-6700 CPU @ 3.40GHZ 8 7,724 61,792 Intel
26 CORE I9-8950HK CPU @ 2.90GHZ 12 5,040 60,480 Intel
27 CORE I7-4770HQ CPU @ 2.20GHZ 8 7,117 56,936 Intel
28 RYZEN 3 3200G 4 14,140 56,560 AMD
29 CORE I5-2500K CPU @ 3.30GHZ 4 13,310 53,240 Intel
30 XEON CPU E3-1220 V2 @ 3.10GHZ 4 11,699 46,796 Intel
31 CORE I5-4590 CPU @ 3.30GHZ 4 11,627 46,508 Intel
32 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 5,766 46,128 Intel
33 RYZEN 7 3700C 8 5,113 40,904 AMD
34 CORE I5-3570 CPU @ 3.40GHZ 4 10,223 40,892 Intel
35 XEON CPU E5-2620 0 @ 2.00GHZ 12 3,089 37,068 Intel
36 CORE I7-9750H CPU @ 2.60GHZ 12 2,531 30,372 Intel
37 CORE I7-8550U CPU @ 1.80GHZ 8 1,490 11,920 Intel
38 CORE I5-3210M CPU @ 2.50GHZ 4 2,191 8,764 Intel
39 CORE I3-6006U CPU @ 2.00GHZ 4 1,981 7,924 Intel