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Research: MYOSINS Folding Project #18302

Project #18302 overview

Project Summary AI Beta

This project looks at different types of myosin proteins found in our bodies. Myosins power muscle movements and cell activities. The project focuses on how fast and strong each type is, which can help us understand diseases like heart problems caused by faulty myosins.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Jeff Lotthammer
Institution
Washington University in St. Louis

Work unit

Atoms
151,374
Core
GRO_A8
Status
Public
Source material

Official Project Description

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

Although superficially similar, myosins actually differ substantially in their properties and distribution in the body.

This project is studying those differences, especially the differences in speed and power.

We are interested in how this might help us understand diseases that result from defects in myosin, including Usher syndrome and, especially, hypertrophic and dilated cardiomyopathies.

Myosin was featured as the PDB Molecule of the Month in June 2001.

Performance data

Hardware Performance for Project 18302

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 21:52:23

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 22,305 713,760 AMD
2 RYZEN 7 5800X 8-CORE 16 38,509 616,144 AMD
3 RYZEN 9 5950X 16-CORE 32 17,785 569,120 AMD
4 RYZEN 9 3900 12-CORE 24 21,511 516,264 AMD
5 RYZEN 9 3900XT 12-CORE 24 19,486 467,664 AMD
6 11TH GEN CORE I9-11900K @ 3.50GHZ 16 25,006 400,096 Intel
7 12TH GEN CORE I7-12700 20 18,208 364,160 Intel
8 RYZEN 7 3800X 8-CORE 16 22,699 363,184 AMD
9 XEON CPU E5-2690 V4 @ 2.60GHZ 28 11,178 312,984 Intel
10 CORE I9-10900X CPU @ 3.70GHZ 20 15,459 309,180 Intel
11 XEON CPU E5-2650 V2 @ 2.60GHZ 32 9,378 300,096 Intel
12 RYZEN 7 3700X 8-CORE 16 15,840 253,440 AMD
13 RYZEN 5 5600X 6-CORE 12 20,109 241,308 AMD
14 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,343 224,232 Intel
15 RYZEN 7 PRO 4750G 16 13,466 215,456 AMD
16 CORE I7-8700 CPU @ 3.20GHZ 12 14,905 178,860 Intel
17 RYZEN 7 2700X EIGHT-CORE 16 9,448 151,168 AMD
18 CORE I7-9700 CPU @ 3.00GHZ 8 18,283 146,264 Intel
19 RYZEN 5 3600 6-CORE 12 12,069 144,828 AMD
20 11TH GEN CORE I5-11400 @ 2.60GHZ 12 8,718 104,616 Intel
21 RYZEN 5 1600 SIX-CORE 12 7,623 91,476 AMD
22 CORE I7-4790K CPU @ 4.00GHZ 8 10,099 80,792 Intel
23 RYZEN 5 3500 6-CORE 6 11,474 68,844 AMD
24 CORE I9-8950HK CPU @ 2.90GHZ 12 4,581 54,972 Intel
25 CORE I7-4770HQ CPU @ 2.20GHZ 8 6,582 52,656 Intel
26 RYZEN 3 3200G 4 12,863 51,452 AMD
27 CORE I5-4570 CPU @ 3.20GHZ 4 11,830 47,320 Intel
28 CORE I5-4590 CPU @ 3.30GHZ 4 11,595 46,380 Intel
29 CORE I3-10100 CPU @ 3.60GHZ 8 5,729 45,832 Intel
30 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 5,329 42,632 Intel
31 XEON CPU E3-1245 V2 @ 3.40GHZ 8 5,209 41,672 Intel
32 CORE I5-3570 CPU @ 3.40GHZ 4 10,185 40,740 Intel
33 XEON CPU E5-2620 0 @ 2.00GHZ 12 2,949 35,388 Intel
34 XEON CPU E31245 @ 3.30GHZ 8 4,289 34,312 Intel
35 11TH GEN CORE I7-1165G7 @ 2.80GHZ 8 3,783 30,264 Intel
36 CORE I5-4300U CPU @ 1.90GHZ 4 4,071 16,284 Intel
37 CORE I3-6006U CPU @ 2.00GHZ 4 2,791 11,164 Intel