PROJECT #18101 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
Here we are testing what has long been the dream on F@h --- adaptive sampling algorithms guided by experimental data. The system used is caspase-7, one of a family of important mediators of apoptosis, and hence of interest for cancer drug design. We have collected experimental hydrogen-deuterium exchange (HDX) data (which informs on the extent of fluctuations of each region of the protein) in both apo (just protein) and holo (protein with another peptide bound) states, and are exploring adaptive sampling algorithms to reproduce the HDX data in each state separately, as well as the differences ('shielding') between them. All data is being made publicly available, and insight into the algorithmic methodology will be published.
This is a project run by Roivant Sciences (formerly Silicon Therapeutics) as was officially announced in this press release: https://foldingathome.org/2021/04/20/maximizing-the-impact-of-foldinghome-by-engaging-industry-collaborators/
PROJECT INFO
Manager(s): Rafal Wiewiora
Institution: Roivant Sciences (Silicon Therapeutics)
Project URL: roivant.com
PROJECT WORK UNIT SUMMARY
Atoms: 86,257
Core: OPENMM_22
Status: Public
PROJECT FOLDING PPD AVERAGES BY GPU
PPDDB data as of Friday, 23 July 2021 12:13:38
|
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
|---|---|---|---|---|---|---|---|
| 1 | GeForce RTX 3090 GA102 [GeForce RTX 3090] |
Nvidia | GA102 | 5,529,878 | 247,222 | 22.37 | 1 hrs 4 mins |
| 2 | GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti] |
Nvidia | GA102 | 5,061,108 | 234,310 | 21.60 | 1 hrs 7 mins |
| 3 | GeForce RTX 3080 GA102 [GeForce RTX 3080] |
Nvidia | GA102 | 4,208,018 | 226,388 | 18.59 | 1 hrs 17 mins |
| 4 | GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448 |
Nvidia | TU102 | 3,705,894 | 216,099 | 17.15 | 1 hrs 24 mins |
| 5 | GeForce RTX 3070 GA104 [GeForce RTX 3070] |
Nvidia | GA104 | 2,632,562 | 193,874 | 13.58 | 2 hrs 46 mins |
| 6 | TITAN Xp GP102 [TITAN Xp] 12150 |
Nvidia | GP102 | 2,413,721 | 187,908 | 12.85 | 2 hrs 52 mins |
| 7 | GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068 |
Nvidia | TU104 | 2,052,948 | 178,430 | 11.51 | 2 hrs 5 mins |
| 8 | GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti] |
Nvidia | GA104 | 2,043,847 | 178,283 | 11.46 | 2 hrs 6 mins |
| 9 | GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380 |
Nvidia | GP102 | 2,027,028 | 177,498 | 11.42 | 2 hrs 6 mins |
| 10 | GeForce RTX 2080 TU104 [GeForce RTX 2080] |
Nvidia | TU104 | 1,984,592 | 173,298 | 11.45 | 2 hrs 6 mins |
| 11 | GeForce RTX 2070 Rev. A TU106 [GeForce RTX 2070 Rev. A] M 7465 |
Nvidia | TU106 | 1,922,443 | 174,657 | 11.01 | 2 hrs 11 mins |
| 12 | Radeon RX 6800/6800 XT / 6900 XT Navi 21 [Radeon RX 6800/6800 XT / 6900 XT] |
AMD | Navi 21 | 1,904,502 | 173,819 | 10.96 | 2 hrs 11 mins |
| 13 | GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER] |
Nvidia | TU106 | 1,742,385 | 169,242 | 10.30 | 2 hrs 20 mins |
| 14 | Radeon RX 6700/6700 XT / 6800M Navi 22 [Radeon RX 6700/6700 XT / 6800M] |
AMD | Navi 22 | 1,706,350 | 168,327 | 10.14 | 2 hrs 22 mins |
| 15 | Radeon RX 5600 OEM/5600 XT/5700/5700 XT Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT] |
AMD | Navi 10 | 1,295,183 | 152,836 | 8.47 | 3 hrs 50 mins |
| 16 | GeForce RTX 2060 Mobile TU106M [GeForce RTX 2060 Mobile] |
Nvidia | TU106M | 1,129,436 | 146,819 | 7.69 | 3 hrs 7 mins |
| 17 | GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER] |
Nvidia | TU116 | 961,355 | 134,378 | 7.15 | 3 hrs 21 mins |
| 18 | Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64] |
AMD | Vega 10 XL/XT | 876,872 | 123,146 | 7.12 | 3 hrs 22 mins |
| 19 | GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372 |
Nvidia | GP106 | 678,037 | 123,378 | 5.50 | 4 hrs 22 mins |
| 20 | GeForce GTX 970 GM204 [GeForce GTX 970] 3494 |
Nvidia | GM204 | 598,053 | 118,436 | 5.05 | 5 hrs 45 mins |
| 21 | P104-100 GP104 [P104-100] |
Nvidia | GP104 | 473,118 | 109,567 | 4.32 | 6 hrs 33 mins |
| 22 | GeForce GTX 1060 3GB GP106 [GeForce GTX 1060 3GB] 3935 |
Nvidia | GP106 | 469,345 | 108,887 | 4.31 | 6 hrs 34 mins |
| 23 | Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590] |
AMD | Ellesmere XT | 401,869 | 103,643 | 3.88 | 6 hrs 11 mins |
| 24 | GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q] |
Nvidia | TU117M | 147,548 | 43,264 | 3.41 | 7 hrs 2 mins |
| 25 | Radeon RX Vega gfx902 raven [Radeon RX Vega gfx902] |
AMD | raven | 51,420 | 45,570 | 1.13 | 21 hrs 16 mins |
PROJECT FOLDING PPD AVERAGES BY CPU BETA
PPDDB data as of Friday, 23 July 2021 12:13:38
|
Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
|---|
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