PROJECT #18100 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
Here we are testing what has long been the dream on F@h --- adaptive sampling algorithms guided by experimental data.
The system used is caspase-7, one of a family of important mediators of apoptosis, and hence of interest for cancer drug design.
We have collected experimental hydrogen-deuterium exchange (HDX) data (which informs on the extent of fluctuations of each region of the protein) in both apo (just protein) and holo (protein with another peptide bound) states, and are exploring adaptive sampling algorithms to reproduce the HDX data in each state separately, as well as the differences ('shielding') between them.
All data is being made publicly available, and insight into the algorithmic methodology will be published. This is a project run by Roivant Sciences (formerly Silicon Therapeutics) as was officially announced in this press release: https://foldingathome.org/2021/04/20/maximizing-the-impact-of-foldinghome-by-engaging-industry-collaborators/.
PROJECT INFO
Manager(s): Rafal Wiewiora
Institution: Roivant Sciences (Silicon Therapeutics)
Project URL: roivant.com
PROJECT WORK UNIT SUMMARY
Atoms: 83,737
Core: OPENMM_22
Status: Public
PROJECT FOLDING PPD AVERAGES BY GPU
PPDDB data as of Friday, 27 May 2022 05:13:26
|
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
|---|---|---|---|---|---|---|---|
| 1 | GeForce RTX 3090 GA102 [GeForce RTX 3090] |
Nvidia | GA102 | 5,933,915 | 246,437 | 24.08 | 1 hrs 60 mins |
| 2 | GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti] |
Nvidia | GA102 | 5,251,195 | 229,877 | 22.84 | 1 hrs 3 mins |
| 3 | GeForce RTX 3080 GA102 [GeForce RTX 3080] |
Nvidia | GA102 | 4,375,912 | 223,639 | 19.57 | 1 hrs 14 mins |
| 4 | GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti] |
Nvidia | GA104 | 3,464,748 | 206,098 | 16.81 | 1 hrs 26 mins |
| 5 | GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448 |
Nvidia | TU102 | 3,379,257 | 203,244 | 16.63 | 1 hrs 27 mins |
| 6 | GeForce RTX 2080 Ti TU102 [GeForce RTX 2080 Ti] M 13448 |
Nvidia | TU102 | 2,571,723 | 187,521 | 13.71 | 2 hrs 45 mins |
| 7 | GeForce RTX 3070 GA104 [GeForce RTX 3070] |
Nvidia | GA104 | 2,523,104 | 186,032 | 13.56 | 2 hrs 46 mins |
| 8 | TITAN Xp GP102 [TITAN Xp] 12150 |
Nvidia | GP102 | 2,423,026 | 183,568 | 13.20 | 2 hrs 49 mins |
| 9 | GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380 |
Nvidia | GP102 | 2,352,074 | 181,630 | 12.95 | 2 hrs 51 mins |
| 10 | RTX A4000 GA104GL [RTX A4000] |
Nvidia | GA104GL | 2,331,303 | 182,119 | 12.80 | 2 hrs 52 mins |
| 11 | GeForce RTX 2080 Super TU104 [GeForce RTX 2080 SUPER] |
Nvidia | TU104 | 2,233,888 | 178,565 | 12.51 | 2 hrs 55 mins |
| 12 | GeForce RTX 2080 Rev. A TU104 [GeForce RTX 2080 Rev. A] 10068 |
Nvidia | TU104 | 2,211,913 | 177,802 | 12.44 | 2 hrs 56 mins |
| 13 | GeForce RTX 3060 Ti Lite Hash Rate GA104 [GeForce RTX 3060 Ti Lite Hash Rate] |
Nvidia | GA104 | 2,106,828 | 174,950 | 12.04 | 2 hrs 60 mins |
| 14 | GeForce RTX 3060 Ti GA104 [GeForce RTX 3060 Ti] |
Nvidia | GA104 | 2,068,097 | 174,408 | 11.86 | 2 hrs 1 mins |
| 15 | Radeon RX 6800/6800 XT / 6900 XT Navi 21 [Radeon RX 6800/6800 XT / 6900 XT] |
AMD | Navi 21 | 1,876,007 | 167,896 | 11.17 | 2 hrs 9 mins |
| 16 | GeForce RTX 2060 Super TU106 [GeForce RTX 2060 SUPER] |
Nvidia | TU106 | 1,714,056 | 163,641 | 10.47 | 2 hrs 17 mins |
| 17 | Radeon RX 6700/6700 XT / 6800M Navi 22 [Radeon RX 6700/6700 XT / 6800M] |
AMD | Navi 22 | 1,535,302 | 148,177 | 10.36 | 2 hrs 19 mins |
| 18 | Radeon VII Vega 20 [Radeon VII] 13,284 |
AMD | Vega 20 | 1,377,952 | 151,563 | 9.09 | 3 hrs 38 mins |
| 19 | Radeon RX 5600 OEM/5600 XT/5700/5700 XT Navi 10 [Radeon RX 5600 OEM/5600 XT/5700/5700 XT] |
AMD | Navi 10 | 1,342,213 | 150,846 | 8.90 | 3 hrs 42 mins |
| 20 | GeForce RTX 2060 TU106 [Geforce RTX 2060] |
Nvidia | TU106 | 1,308,743 | 148,752 | 8.80 | 3 hrs 44 mins |
| 21 | GeForce RTX 3060 Mobile / Max-Q GA106M [GeForce RTX 3060 Mobile / Max-Q] |
Nvidia | GA106M | 1,267,496 | 147,577 | 8.59 | 3 hrs 48 mins |
| 22 | GeForce RTX 2060 Mobile TU106M [GeForce RTX 2060 Mobile] |
Nvidia | TU106M | 1,202,205 | 146,101 | 8.23 | 3 hrs 55 mins |
| 23 | GeForce GTX 1070 GP104 [GeForce GTX 1070] 6463 |
Nvidia | GP104 | 1,130,692 | 142,520 | 7.93 | 3 hrs 2 mins |
| 24 | GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER] |
Nvidia | TU116 | 1,024,482 | 137,660 | 7.44 | 3 hrs 13 mins |
| 25 | Radeon RX Vega 56/64 Vega 10 XL/XT [Radeon RX Vega 56/64] |
AMD | Vega 10 XL/XT | 901,797 | 129,821 | 6.95 | 3 hrs 27 mins |
| 26 | GeForce GTX 1060 6GB GP106 [GeForce GTX 1060 6GB] 4372 |
Nvidia | GP106 | 654,118 | 118,563 | 5.52 | 4 hrs 21 mins |
| 27 | P104-100 GP104 [P104-100] |
Nvidia | GP104 | 472,857 | 106,391 | 4.44 | 5 hrs 24 mins |
| 28 | GeForce GTX 1650 Mobile / Max-Q TU117M [GeForce GTX 1650 Mobile / Max-Q] |
Nvidia | TU117M | 431,665 | 103,782 | 4.16 | 6 hrs 46 mins |
| 29 | Radeon RX 470/480/570/580/590 Ellesmere XT [Radeon RX 470/480/570/580/590] |
AMD | Ellesmere XT | 430,081 | 103,134 | 4.17 | 6 hrs 45 mins |
| 30 | GeForce GTX 1080 GP104 [GeForce GTX 1080] 8873 |
Nvidia | GP104 | 397,021 | 91,089 | 4.36 | 6 hrs 30 mins |
| 31 | P106-100 GP106 [P106-100] |
Nvidia | GP106 | 334,466 | 94,751 | 3.53 | 7 hrs 48 mins |
| 32 | GeForce GTX 960 GM206 [GeForce GTX 960] 2308 |
Nvidia | GM206 | 239,046 | 86,041 | 2.78 | 9 hrs 38 mins |
PROJECT FOLDING PPD AVERAGES BY CPU BETA
PPDDB data as of Friday, 27 May 2022 05:13:26
|
Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
|---|
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