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Research: COVID-19 Folding Project #14815

Project #14815 overview

Project Summary AI Beta

Folding@home is using CPU power to simulate proteins from the COVID-19 virus. This helps researchers learn how these proteins work and find potential drugs. The project focuses on the main protease, a key enzyme in the virus's life cycle. Updates are available on the Folding@home website.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Prof. Vincent Voelz
Institution
Temple University

Work unit

Atoms
55,625
Core
GRO_A7
Status
Public
Source material

Official Project Description

CORONAVIRUS PROJECT These projects are part of Folding@home’s efforts to assist researchers around the world taking up the global fight against COVID-19.

At the time of release, this is the latest news update: https://foldingathome.org/2020/03/10/covid19-update/ These projects are CPU projects to simulate COVID-19 proteins to learn about their dynamics and function.

These supplement high-priority GPU projects of the main protease as well as the COVID-19 receptor binding domains.

All can be considered potential drug targets. Please stay tuned to https://foldingathome.org/news/ for more current updates. ALL of these projects are Coronavirus SARS-CoV-2 main protease in complex with a potential inhibitor: series project number ------- ------- 72_RL 14800
387_RL 14801
387_RL 14802
387_RL 14803
387_RL 14804
387_RL 14805
387_RL 14806
387_RL 14807
387_RL 14808
AGG_RL 14809
AGG_RL 14810
AGG_RL 14811
AGG_RL 14812
AGG_RL 14813
AGG_RL 14814
AGG_RL 14815
AGG_RL 14816
BRO_RL 14717
BRO_RL 14718
BRO_RL 14719
BRO_RL 14820
MLTN_RL 14821
MS0323_RL 14822
MS0326_RL 14823
MS0326_RL 14824
MS0331_RL 14825
MS0406_RL 14852
MS0406-2_RL 14854
GUZ_RL 14858.

Performance data

Hardware Performance for Project 14815

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:06:27

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN THREADRIPPER 3960X 24-CORE 48 14,439 693,072 AMD
2 RYZEN 9 5950X 16-CORE 32 15,284 489,088 AMD
3 RYZEN 9 5900X 12-CORE 24 14,309 343,416 AMD
4 RYZEN 9 3950X 16-CORE 32 9,546 305,472 AMD
5 RYZEN THREADRIPPER 2970WX 24-CORE 48 5,621 269,808 AMD
6 RYZEN 9 3900X 12-CORE 24 10,354 248,496 AMD
7 CORE I9-9980XE CPU @ 3.00GHZ 36 6,639 239,004 Intel
8 CORE I9-9900K CPU @ 3.60GHZ 16 14,781 236,496 Intel
9 RYZEN 7 3800X 8-CORE 16 12,125 194,000 AMD
10 RYZEN THREADRIPPER 2950X 16-CORE 32 5,997 191,904 AMD
11 RYZEN THREADRIPPER 1920X 12-CORE 24 6,624 158,976 AMD
12 XEON W-2245 CPU @ 3.90GHZ 16 8,612 137,792 Intel
13 RYZEN 7 4800H 16 8,525 136,400 AMD
14 CORE I7-9700K CPU @ 3.60GHZ 8 16,917 135,336 Intel
15 RYZEN 7 2700X EIGHT-CORE 16 8,428 134,848 AMD
16 RYZEN 5 3600X 6-CORE 12 10,909 130,908 AMD
17 RYZEN 7 3700X 8-CORE 16 7,418 118,688 AMD
18 XEON CPU E5-2690 V2 @ 3.00GHZ 20 5,761 115,220 Intel
19 RYZEN 5 3600 6-CORE 12 8,652 103,824 AMD
20 RYZEN 5 3500 6-CORE 6 16,248 97,488 AMD
21 CORE I7-9700 CPU @ 3.00GHZ 8 11,751 94,008 Intel
22 XEON CPU E5-2650 V2 @ 2.60GHZ 32 2,525 80,800 Intel
23 CORE I7-8700 CPU @ 3.20GHZ 12 6,448 77,376 Intel
24 CORE I7-10710U CPU @ 1.10GHZ 12 6,276 75,312 Intel
25 RYZEN 7 1700 EIGHT-CORE 16 4,118 65,888 AMD
26 XEON CPU E5-2630 0 @ 2.30GHZ 24 2,630 63,120 Intel
27 RYZEN 5 2600X SIX-CORE 12 5,084 61,008 AMD
28 RYZEN 5 2600 SIX-CORE 12 3,933 47,196 AMD
29 CORE I7-6700K CPU @ 4.00GHZ 8 5,732 45,856 Intel
30 CORE I7-9700F CPU @ 3.00GHZ 8 5,241 41,928 Intel
31 RYZEN 5 4600HS 12 3,306 39,672 AMD
32 CORE I5-7600 CPU @ 3.50GHZ 4 9,587 38,348 Intel
33 FX-8350 EIGHT-CORE 8 3,142 25,136 AMD
34 CORE I7-2600K CPU @ 3.40GHZ 8 3,022 24,176 Intel
35 CORE I7-8705G CPU @ 3.10GHZ 8 2,762 22,096 Intel
36 XEON CPU X5365 @ 3.00GHZ 8 2,625 21,000 Intel
37 CORE I5-8265U CPU @ 1.60GHZ 8 2,492 19,936 Intel
38 CORE I7-3632QM CPU @ 2.20GHZ 8 2,219 17,752 Intel
39 CORE I3-6100 CPU @ 3.70GHZ 4 3,642 14,568 Intel
40 CORE I7-8700K CPU @ 3.70GHZ 12 1,071 12,852 Intel
41 FX-8320 EIGHT-CORE 8 1,600 12,800 AMD
42 A8-6410 APU 4 79 316 AMD