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Research: COVID-19 Folding Project #14812

Project #14812 overview

Project Summary AI Beta

Folding@home is using computer power to study proteins from the COVID-19 virus. This helps scientists learn how the virus works and find potential drugs to fight it. The project focuses on the main protease, a key protein for the virus to replicate. People can contribute by running simulations on their computers.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Prof. Vincent Voelz
Institution
Temple University

Work unit

Atoms
55,625
Core
GRO_A7
Status
Public
Source material

Official Project Description

CORONAVIRUS PROJECT These projects are part of Folding@home’s efforts to assist researchers around the world taking up the global fight against COVID-19.

At the time of release, this is the latest news update: https://foldingathome.org/2020/03/10/covid19-update/ These projects are CPU projects to simulate COVID-19 proteins to learn about their dynamics and function.

These supplement high-priority GPU projects of the main protease as well as the COVID-19 receptor binding domains.

All can be considered potential drug targets. Please stay tuned to https://foldingathome.org/news/ for more current updates. ALL of these projects are Coronavirus SARS-CoV-2 main protease in complex with a potential inhibitor: series project number ------- ------- 72_RL 14800
387_RL 14801
387_RL 14802
387_RL 14803
387_RL 14804
387_RL 14805
387_RL 14806
387_RL 14807
387_RL 14808
AGG_RL 14809
AGG_RL 14810
AGG_RL 14811
AGG_RL 14812
AGG_RL 14813
AGG_RL 14814
AGG_RL 14815
AGG_RL 14816
BRO_RL 14717
BRO_RL 14718
BRO_RL 14719
BRO_RL 14820
MLTN_RL 14821
MS0323_RL 14822
MS0326_RL 14823
MS0326_RL 14824
MS0331_RL 14825
MS0406_RL 14852
MS0406-2_RL 14854
GUZ_RL 14858.

Performance data

Hardware Performance for Project 14812

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:06:30

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN THREADRIPPER 3960X 24-CORE 48 13,688 657,024 AMD
2 RYZEN 9 5950X 16-CORE 32 12,827 410,464 AMD
3 RYZEN 9 5900X 12-CORE 24 14,209 341,016 AMD
4 RYZEN THREADRIPPER 2970WX 24-CORE 48 5,613 269,424 AMD
5 RYZEN 9 3900X 12-CORE 24 11,081 265,944 AMD
6 CORE I9-9900K CPU @ 3.60GHZ 16 15,128 242,048 Intel
7 CORE I9-9980XE CPU @ 3.00GHZ 36 6,662 239,832 Intel
8 RYZEN 7 3800X 8-CORE 16 10,504 168,064 AMD
9 RYZEN THREADRIPPER 1920X 12-CORE 24 6,872 164,928 AMD
10 RYZEN 7 2700X EIGHT-CORE 16 9,798 156,768 AMD
11 RYZEN 7 4800H 16 9,513 152,208 AMD
12 XEON W-2245 CPU @ 3.90GHZ 16 8,520 136,320 Intel
13 RYZEN 5 3600X 6-CORE 12 11,082 132,984 AMD
14 RYZEN 7 3700X 8-CORE 16 8,035 128,560 AMD
15 XEON CPU E5-2690 V2 @ 3.00GHZ 20 5,625 112,500 Intel
16 RYZEN 5 3600 6-CORE 12 8,601 103,212 AMD
17 RYZEN 5 3500 6-CORE 6 16,471 98,826 AMD
18 CORE I7-9700 CPU @ 3.00GHZ 8 11,560 92,480 Intel
19 CORE I7-8700K CPU @ 3.70GHZ 12 6,637 79,644 Intel
20 CORE I5-10400 CPU @ 2.90GHZ 12 6,200 74,400 Intel
21 CORE2 DUO CPU T7700 @ 2.40GHZ 12 6,050 72,600 Intel
22 CORE I7-10710U CPU @ 1.10GHZ 12 5,837 70,044 Intel
23 RYZEN 7 1700 EIGHT-CORE 16 4,302 68,832 AMD
24 CORE I5-8400 CPU @ 2.80GHZ 6 11,455 68,730 Intel
25 CORE I7-9700K CPU @ 3.60GHZ 8 8,193 65,544 Intel
26 RYZEN 5 2600X SIX-CORE 12 4,998 59,976 AMD
27 CORE I7-6700K CPU @ 4.00GHZ 8 6,377 51,016 Intel
28 RYZEN 5 2600 SIX-CORE 12 3,943 47,316 AMD
29 CORE I5-7600 CPU @ 3.50GHZ 4 10,419 41,676 Intel
30 CORE I7-4790K CPU @ 4.00GHZ 8 4,270 34,160 Intel
31 CORE I7-6700T CPU @ 2.80GHZ 8 4,150 33,200 Intel
32 RYZEN 5 4600HS 12 2,316 27,792 AMD
33 CORE I5-8265U CPU @ 1.60GHZ 8 2,587 20,696 Intel
34 XEON CPU X5365 @ 3.00GHZ 8 2,575 20,600 Intel
35 CORE I7-8705G CPU @ 3.10GHZ 8 1,517 12,136 Intel
36 FX-8320 EIGHT-CORE 8 1,420 11,360 AMD
37 CORE I5-4300U CPU @ 1.90GHZ 4 2,348 9,392 Intel
38 CORE I3-6006U CPU @ 2.00GHZ 4 1,511 6,044 Intel
39 CORE I5-8250U CPU @ 1.60GHZ 8 517 4,136 Intel
40 CELERON(R) CPU G550 @ 2.60GHZ 2 1,156 2,312 Intel