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Research: COVID-19 Folding Project #14810

Project #14810 overview

Project Summary AI Beta

Folding@home is using CPU power to simulate coronavirus proteins. This helps researchers understand how these proteins work and find potential drug targets. The project focuses on the main protease, a key enzyme in the virus's life cycle. For more info, visit https://foldingathome.org/news/
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Prof. Vincent Voelz
Institution
Temple University

Work unit

Atoms
55,625
Core
GRO_A7
Status
Public
Source material

Official Project Description

CORONAVIRUS PROJECT These projects are part of Folding@home’s efforts to assist researchers around the world taking up the global fight against COVID-19.

At the time of release, this is the latest news update: https://foldingathome.org/2020/03/10/covid19-update/ These projects are CPU projects to simulate COVID-19 proteins to learn about their dynamics and function.

These supplement high-priority GPU projects of the main protease as well as the COVID-19 receptor binding domains.

All can be considered potential drug targets. Please stay tuned to https://foldingathome.org/news/ for more current updates. ALL of these projects are Coronavirus SARS-CoV-2 main protease in complex with a potential inhibitor: series project number ------- ------- 72_RL 14800
387_RL 14801
387_RL 14802
387_RL 14803
387_RL 14804
387_RL 14805
387_RL 14806
387_RL 14807
387_RL 14808
AGG_RL 14809
AGG_RL 14810
AGG_RL 14811
AGG_RL 14812
AGG_RL 14813
AGG_RL 14814
AGG_RL 14815
AGG_RL 14816
BRO_RL 14717
BRO_RL 14718
BRO_RL 14719
BRO_RL 14820
MLTN_RL 14821
MS0323_RL 14822
MS0326_RL 14823
MS0326_RL 14824
MS0331_RL 14825
MS0406_RL 14852
MS0406-2_RL 14854
GUZ_RL 14858.

Performance data

Hardware Performance for Project 14810

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:06:32

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN THREADRIPPER 3960X 24-CORE 48 13,561 650,928 AMD
2 RYZEN 9 5950X 16-CORE 32 14,298 457,536 AMD
3 RYZEN 9 5900X 12-CORE 24 13,183 316,392 AMD
4 RYZEN 9 3950X 16-CORE 32 8,999 287,968 AMD
5 XEON CPU E5-2667 V4 @ 3.20GHZ 32 8,715 278,880 Intel
6 RYZEN THREADRIPPER 2970WX 24-CORE 48 5,646 271,008 AMD
7 CORE I9-9980XE CPU @ 3.00GHZ 36 6,818 245,448 Intel
8 RYZEN 9 3900X 12-CORE 24 10,174 244,176 AMD
9 RYZEN THREADRIPPER 2950X 16-CORE 32 6,051 193,632 AMD
10 RYZEN 7 3800X 8-CORE 16 10,529 168,464 AMD
11 RYZEN THREADRIPPER 1920X 12-CORE 24 6,961 167,064 AMD
12 RYZEN 7 2700X EIGHT-CORE 16 8,970 143,520 AMD
13 CORE I7-9700K CPU @ 3.60GHZ 8 17,327 138,616 Intel
14 XEON W-2245 CPU @ 3.90GHZ 16 8,641 138,256 Intel
15 RYZEN 5 3600X 6-CORE 12 10,662 127,944 AMD
16 RYZEN 7 4800H 16 7,863 125,808 AMD
17 RYZEN 7 3700X 8-CORE 16 7,476 119,616 AMD
18 XEON CPU E5-2690 V2 @ 3.00GHZ 20 5,623 112,460 Intel
19 RYZEN 5 3600 6-CORE 12 8,855 106,260 AMD
20 XEON CPU E5-2650 V2 @ 2.60GHZ 32 3,295 105,440 Intel
21 CORE I7-9700 CPU @ 3.00GHZ 8 11,599 92,792 Intel
22 RYZEN 5 3600XT 6-CORE 12 7,677 92,124 AMD
23 CORE I7-8700K CPU @ 3.70GHZ 12 7,592 91,104 Intel
24 CORE I7-10710U CPU @ 1.10GHZ 12 6,283 75,396 Intel
25 RYZEN 5 5600X 6-CORE 12 5,767 69,204 AMD
26 XEON CPU E5-2630 0 @ 2.30GHZ 24 2,772 66,528 Intel
27 RYZEN 7 1700 EIGHT-CORE 16 4,062 64,992 AMD
28 RYZEN 5 2600X SIX-CORE 12 4,959 59,508 AMD
29 RYZEN 5 4600HS 12 3,851 46,212 AMD
30 RYZEN 5 2600 SIX-CORE 12 3,844 46,128 AMD
31 CORE I7-6700K CPU @ 4.00GHZ 8 5,655 45,240 Intel
32 CORE I5-7600 CPU @ 3.50GHZ 4 9,718 38,872 Intel
33 CORE I5-4570S CPU @ 2.90GHZ 4 9,516 38,064 Intel
34 CORE I7-6700 CPU @ 3.40GHZ 8 4,227 33,816 Intel
35 CORE I7-6700T CPU @ 2.80GHZ 8 4,059 32,472 Intel
36 CORE I7-2600K CPU @ 3.40GHZ 8 3,765 30,120 Intel
37 CORE I7-3770 CPU @ 3.40GHZ 8 3,100 24,800 Intel
38 CORE I5-8265U CPU @ 1.60GHZ 8 2,753 22,024 Intel
39 XEON CPU X5365 @ 3.00GHZ 8 2,722 21,776 Intel
40 CORE I7-3632QM CPU @ 2.20GHZ 8 1,743 13,944 Intel
41 CORE I5-8400 CPU @ 2.80GHZ 6 2,093 12,558 Intel
42 CORE I7-8705G CPU @ 3.10GHZ 8 1,443 11,544 Intel
43 CORE I5-4300U CPU @ 1.90GHZ 4 2,427 9,708 Intel
44 XEON CPU L5420 @ 2.50GHZ 4 2,043 8,172 Intel
45 CORE I3-6006U CPU @ 2.00GHZ 4 1,692 6,768 Intel
46 RYZEN 5 3500U 8 526 4,208 AMD
47 A8-6410 APU 4 77 308 AMD