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Research: MYOSINS Folding Project #14482

Project #14482 overview

Project Summary AI Beta

This project studies myosins, proteins that power body movements like muscle contractions and cell functions. Scientists want to understand how drugs could fix problems with myosin, which cause heart diseases like cardiomyopathy and heart failure.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Artur Meller
Institution
Washington University in St. Louis

Work unit

Atoms
172,277
Core
GRO_A7
Status
Public
Source material

Official Project Description

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

We are interested in understanding the mechanistic basis of drugs that might be used to treat defects in myosin, including hypertrophic and dilated cardiomyopathies as well as heart failure.

Myosin was featured as the PDB Molecule of the Month in June 2001.

Performance data

Hardware Performance for Project 14482

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:06:47

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN THREADRIPPER 3970X 32-CORE 64 17,026 1,089,664 AMD
2 RYZEN THREADRIPPER 3960X 24-CORE 48 19,470 934,560 AMD
3 RYZEN 9 3950X 16-CORE 32 15,349 491,168 AMD
4 CORE I9-10980XE CPU @ 3.00GHZ 36 11,331 407,916 Intel
5 XEON CPU E5-2686 V4 @ 2.30GHZ 36 10,479 377,244 Intel
6 RYZEN 9 3900X 12-CORE 24 15,492 371,808 AMD
7 RYZEN 9 3900XT 12-CORE 24 14,087 338,088 AMD
8 RYZEN THREADRIPPER 1920X 12-CORE 24 7,976 191,424 AMD
9 RYZEN 7 3700X 8-CORE 16 10,660 170,560 AMD
10 CORE I9-9900KF CPU @ 3.60GHZ 16 10,087 161,392 Intel
11 XEON W-2245 CPU @ 3.90GHZ 16 9,599 153,584 Intel
12 CORE I9-7940X CPU @ 3.10GHZ 28 5,353 149,884 Intel
13 RYZEN 5 3600X 6-CORE 12 11,492 137,904 AMD
14 RYZEN 5 3600 6-CORE 12 11,136 133,632 AMD
15 XEON CPU E5-2660 0 @ 2.20GHZ 32 4,064 130,048 Intel
16 CORE I9-9900K CPU @ 3.60GHZ 16 7,574 121,184 Intel
17 RYZEN 7 3800X 8-CORE 16 7,213 115,408 AMD
18 RYZEN 7 2700X EIGHT-CORE 16 6,549 104,784 AMD
19 CORE I3-10100 CPU @ 3.60GHZ 8 12,200 97,600 Intel
20 CORE I7-9700 CPU @ 3.00GHZ 8 11,890 95,120 Intel
21 XEON CPU E5-2690 V2 @ 3.00GHZ 20 4,303 86,060 Intel
22 CORE I5-10400F CPU @ 2.90GHZ 12 6,188 74,256 Intel
23 RYZEN 7 1700 EIGHT-CORE 16 4,396 70,336 AMD
24 XEON CPU E5-2620 V2 @ 2.10GHZ 24 2,708 64,992 Intel
25 CORE I7-4790K CPU @ 4.00GHZ 8 5,931 47,448 Intel
26 CORE I7-8705G CPU @ 3.10GHZ 8 4,931 39,448 Intel
27 CORE I5-9400 CPU @ 2.90GHZ 6 6,508 39,048 Intel
28 CORE I3-8100 CPU @ 3.60GHZ 4 8,527 34,108 Intel
29 CORE I7-6700HQ CPU @ 2.60GHZ 8 2,580 20,640 Intel
30 CORE I3-6006U CPU @ 2.00GHZ 4 1,941 7,764 Intel