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Research: MYOSINS Folding Project #14480

Project #14480 overview

Project Summary AI Beta

This project studies myosin proteins, which power muscle contractions and cell movement. Scientists want to understand how drugs can fix problems with myosin that cause heart diseases like cardiomyopathy and heart failure. Myosin was even featured as a special protein of the month!
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Artur Meller
Institution
Washington University in St. Louis

Work unit

Atoms
172,025
Core
GRO_A7
Status
Public
Source material

Official Project Description

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

We are interested in understanding the mechanistic basis of drugs that might be used to treat defects in myosin, including hypertrophic and dilated cardiomyopathies as well as heart failure.

Myosin was featured as the PDB Molecule of the Month in June 2001.

Performance data

Hardware Performance for Project 14480

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:06:49

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN THREADRIPPER 3960X 24-CORE 48 23,837 1,144,176 AMD
2 RYZEN 9 3950X 16-CORE 32 18,832 602,624 AMD
3 RYZEN 9 3900X 12-CORE 24 14,419 346,056 AMD
4 CORE I9-10980XE CPU @ 3.00GHZ 36 8,290 298,440 Intel
5 RYZEN 9 3900XT 12-CORE 24 11,677 280,248 AMD
6 XEON CPU E5-2686 V4 @ 2.30GHZ 36 5,991 215,676 Intel
7 CORE I9-10900X CPU @ 3.70GHZ 20 10,074 201,480 Intel
8 RYZEN 7 3800X 8-CORE 16 11,780 188,480 AMD
9 RYZEN 7 3700X 8-CORE 16 10,787 172,592 AMD
10 RYZEN 5 3600X 6-CORE 12 13,200 158,400 AMD
11 CORE I9-9900K CPU @ 3.60GHZ 16 9,646 154,336 Intel
12 RYZEN 5 3600 6-CORE 12 11,149 133,788 AMD
13 CORE I7-8700K CPU @ 3.70GHZ 12 10,142 121,704 Intel
14 CORE I7-9700 CPU @ 3.00GHZ 8 12,150 97,200 Intel
15 XEON CPU E5-2690 V2 @ 3.00GHZ 20 4,276 85,520 Intel
16 CORE I7-9700K CPU @ 3.60GHZ 8 10,669 85,352 Intel
17 CORE I9-9880H CPU @ 2.30GHZ 16 4,886 78,176 Intel
18 CORE I5-10400F CPU @ 2.90GHZ 12 6,163 73,956 Intel
19 XEON CPU E5-2620 V2 @ 2.10GHZ 24 2,810 67,440 Intel
20 CORE I7-4790K CPU @ 4.00GHZ 8 6,339 50,712 Intel
21 CORE I7-8705G CPU @ 3.10GHZ 8 4,933 39,464 Intel
22 CORE I3-8100 CPU @ 3.60GHZ 4 8,614 34,456 Intel
23 CORE I7-3520M CPU @ 2.90GHZ 4 2,740 10,960 Intel