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Research: MYOSINS Folding Project #14483

Project #14483 overview

Project Summary AI Beta

This project studies myosins, proteins that power our bodies' movements. Scientists want to understand how drugs can fix problems with myosins, like those causing heart conditions. Myosin is so important it was even named the Molecule of the Month by scientists!
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Artur Meller
Institution
Washington University in St. Louis

Work unit

Atoms
172,029
Core
GRO_A7
Status
Public
Source material

Official Project Description

This project simulates several myosins found in the human body.

Myosins are the proteins responsible for most of the force generated by the body, from the contraction of muscles to the movement of materials around the cell.

We are interested in understanding the mechanistic basis of drugs that might be used to treat defects in myosin, including hypertrophic and dilated cardiomyopathies as well as heart failure.

Myosin was featured as the PDB Molecule of the Month in June 2001.

Performance data

Hardware Performance for Project 14483

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:06:46

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN THREADRIPPER 3970X 32-CORE 64 18,851 1,206,464 AMD
2 RYZEN THREADRIPPER 3960X 24-CORE 48 21,663 1,039,824 AMD
3 RYZEN 9 3950X 16-CORE 32 17,684 565,888 AMD
4 XEON CPU E5-2686 V4 @ 2.30GHZ 36 11,619 418,284 Intel
5 RYZEN 9 3900X 12-CORE 24 15,802 379,248 AMD
6 RYZEN 9 3900XT 12-CORE 24 13,583 325,992 AMD
7 CORE I9-10980XE CPU @ 3.00GHZ 36 6,877 247,572 Intel
8 RYZEN 7 3700X 8-CORE 16 12,788 204,608 AMD
9 CORE I9-7920X CPU @ 2.90GHZ 24 8,389 201,336 Intel
10 CORE I9-10900X CPU @ 3.70GHZ 20 8,683 173,660 Intel
11 CORE I7-8700K CPU @ 3.70GHZ 12 12,947 155,364 Intel
12 RYZEN THREADRIPPER 1920X 12-CORE 24 5,543 133,032 AMD
13 RYZEN 5 3600 6-CORE 12 10,512 126,144 AMD
14 CORE I9-7940X CPU @ 3.10GHZ 28 4,356 121,968 Intel
15 CORE I9-9900K CPU @ 3.60GHZ 16 7,198 115,168 Intel
16 RYZEN 7 3800X 8-CORE 16 6,706 107,296 AMD
17 CORE I7-9700 CPU @ 3.00GHZ 8 12,115 96,920 Intel
18 RYZEN 5 3500 6-CORE 6 12,709 76,254 AMD
19 RYZEN 5 2600X SIX-CORE 12 6,329 75,948 AMD
20 CORE I9-9880H CPU @ 2.30GHZ 16 3,593 57,488 Intel
21 RYZEN 7 2700X EIGHT-CORE 16 3,514 56,224 AMD
22 CORE I7-9850H CPU @ 2.60GHZ 12 3,689 44,268 Intel
23 CORE I5-9400 CPU @ 2.90GHZ 6 6,906 41,436 Intel
24 CORE I3-8100 CPU @ 3.60GHZ 4 8,490 33,960 Intel
25 CORE I7-3520M CPU @ 2.90GHZ 4 2,699 10,796 Intel
26 CORE I3-6006U CPU @ 2.00GHZ 4 1,908 7,632 Intel