PROJECT #18903 RESEARCH FOR SIGNALING PROTEIN
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

Impact of mutations on signaling proteins Mutations in proteins are often found to have dramatic functional consequences through changes in conformational dynamics, ligand binding, and association with signaling partners.

These changes sometimes lead to pathological outcomes.

Additionally, proteins involved in cell signaling are the target of over half of approved drugs.

This project aims to understand how a small number of mutations in signaling proteins can cause a dramatic change in how they modulate cell signaling pathways..

PROJECT INFO

Manager(s): Jiming Chen

Institution: University of Illinois at Urbana-Champaign

PROJECT WORK UNIT SUMMARY

Atoms: 37,892

Core: OPENMM_22

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 02 October 2022 12:16:26

Rank Project	Model Name Folding@Home Identifier	Make Brand	GPU Model	PPD Average	Points WU Average	WUs Day Average	WU Time Average
1	GeForce RTX 3090 GA102 [GeForce RTX 3090]	Nvidia	GA102	4,881,383	79,916	61.08	0 ^hrs 24 ^mins
2	GeForce RTX 3080 Ti GA102 [GeForce RTX 3080 Ti]	Nvidia	GA102	3,324,033	70,151	47.38	1 ^hrs 30 ^mins
3	GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448	Nvidia	TU102	3,113,531	68,469	45.47	1 ^hrs 32 ^mins
4	GeForce RTX 3070 Ti GA104 [GeForce RTX 3070 Ti]	Nvidia	GA104	3,072,043	67,608	45.44	1 ^hrs 32 ^mins
5	GeForce RTX 3070 GA104 [GeForce RTX 3070]	Nvidia	GA104	2,812,831	66,425	42.35	1 ^hrs 34 ^mins
6	RTX A5000 GA102GL [RTX A5000]	Nvidia	GA102GL	2,528,240	64,376	39.27	1 ^hrs 37 ^mins
7	GeForce RTX 2060 TU104 [GeForce RTX 2060]	Nvidia	TU104	2,194,872	68,763	31.92	1 ^hrs 45 ^mins
8	GeForce RTX 3080 Lite Hash Rate GA102 [GeForce RTX 3080 Lite Hash Rate]	Nvidia	GA102	2,094,565	60,607	34.56	1 ^hrs 42 ^mins
9	GeForce GTX 1660 SUPER TU116 [GeForce GTX 1660 SUPER]	Nvidia	TU116	1,181,256	47,384	24.93	1 ^hrs 58 ^mins
10	Tesla M40 GM200GL [Tesla M40] 6844	Nvidia	GM200GL	846,914	44,320	19.11	1 ^hrs 15 ^mins
11	GeForce GTX 970 GM204 [GeForce GTX 970] 3494	Nvidia	GM204	437,814	35,978	12.17	2 ^hrs 58 ^mins
12	P106-090 GP106 [P106-090]	Nvidia	GP106	316,126	31,739	9.96	2 ^hrs 25 ^mins
13	GeForce GTX 950 GM206 [GeForce GTX 950] 1572	Nvidia	GM206	206,828	27,010	7.66	3 ^hrs 8 ^mins
14	GeForce GTX 770 GK104 [GeForce GTX 770] 3213	Nvidia	GK104	90,492	21,136	4.28	6 ^hrs 36 ^mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA