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Research: CANCER Folding Project #18495

Project #18495 overview

Project Summary AI Beta

This project is testing a new computer method to predict how well drugs dissolve in the body. It uses simulations to figure out something called logP, which tells us how much a drug likes water versus fat. This helps scientists develop better medicines.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Prof. Vincent Voelz
Institution
Temple University

Work unit

Atoms
17,400
Core
0xa8
Status
Public
Source material

Official Project Description

A key challenge in computational drug discovery is developing and testing methods to predict experimental partition coefficients for the relative solubility of organic molecules in aqueous vs.

non-polar media.

The logarithm of the partition coeffient, logP, is an important predictor of lipophilicity, which dictates the bioavailability of drugs.

This CPU project is testing expanded-ensemble (EE) simulations as a method for the calculation of logP..

Performance data

Hardware Performance for Project 18495

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 21:50:47

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 9950X 16-CORE 32 53,307 1,705,824 AMD
2 RYZEN THREADRIPPER 7980X 64-CORES 64 22,219 1,422,016 AMD
3 RYZEN 9 5950X 16-CORE 32 26,728 855,296 AMD
4 RYZEN 9 7950X3D 16-CORE 32 23,004 736,128 AMD
5 RYZEN 9 7900X 12-CORE 24 30,277 726,648 AMD
6 RYZEN 9 7900 12-CORE 24 26,518 636,432 AMD
7 RYZEN 9 3950X 16-CORE 32 17,822 570,304 AMD
8 RYZEN 7 7800X3D 8-CORE 16 35,475 567,600 AMD
9 RYZEN 7 5800X 8-CORE 16 32,296 516,736 AMD
10 RYZEN 7 7700X 8-CORE 16 31,653 506,448 AMD
11 CORE I9-14900KF 24 20,693 496,632 Intel
12 RYZEN 7 7700 8-CORE 16 30,234 483,744 AMD
13 12TH GEN CORE I7-12700F 20 23,875 477,500 Intel
14 RYZEN 7 5700X3D 8-CORE 16 27,619 441,904 AMD
15 RYZEN 7 5700X 8-CORE 16 27,267 436,272 AMD
16 RYZEN 7 5800X3D 8-CORE 16 21,390 342,240 AMD
17 RYZEN 7 5700G 16 20,927 334,832 AMD
18 RYZEN 9 3900X 12-CORE 24 11,779 282,696 AMD
19 13TH GEN CORE I5-13600K 14 20,115 281,610 Intel
20 RYZEN THREADRIPPER 3960X 24-CORE 48 5,508 264,384 AMD
21 13TH GEN CORE I7-13700 24 9,956 238,944 Intel
22 XEON CPU E5-2683 V4 @ 2.10GHZ 32 6,108 195,456 Intel
23 RYZEN 7 3700X 8-CORE 16 11,954 191,264 AMD
24 RYZEN 5 5600 6-CORE 12 15,125 181,500 AMD
25 11TH GEN CORE I7-11800H @ 2.30GHZ 16 9,138 146,208 Intel
26 RYZEN 9 3900XT 12-CORE 24 5,845 140,280 AMD
27 CORE I5-14500 20 5,327 106,540 Intel
28 11TH GEN CORE I7-11700F @ 2.50GHZ 16 6,631 106,096 Intel
29 RYZEN 5 5600X 6-CORE 12 5,561 66,732 AMD
30 XEON CPU X5660 @ 2.80GHZ 24 2,304 55,296 Intel
31 RYZEN 7 4800U 16 3,121 49,936 AMD
32 12TH GEN CORE I5-12600K 16 2,288 36,608 Intel