PROJECT #16995 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These projects aim to simulate the dynamics of a large number of designed mini-proteins (< 50 residues), to establish the ability of molecular simulations to accurately predict thermodynamic and kinetic effects of designed mutations.

We aim to develop a library of experimental and simulation data so we can compare the performance of different techniques for computational protein design, such as adaptive sampling.

Prediction and design of mini-protein structure and dynamics is highly relevant to developing new biotherapeutics for a wide range of human diseases. Projects 16935, 16958, and 16995 are chignolin, a small designed hairpin peptide..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 12,120

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 22 May 2022 15:22:34

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 22 May 2022 15:22:34

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 CORE I9-10850K CPU @ 3.60GHZ 20 28,753 575,060 Intel
2 RYZEN 9 3900 12-CORE 24 21,935 526,440 AMD
3 RYZEN 7 5800X 8-CORE 16 31,380 502,080 AMD
4 RYZEN 9 5950X 16-CORE 32 14,694 470,208 AMD
5 RYZEN 7 5800X3D 8-CORE 16 28,557 456,912 AMD
6 EPYC 7V12 64-CORE 64 7,131 456,384 AMD
7 11TH GEN CORE I7-11700K @ 3.60GHZ 16 27,716 443,456 Intel
8 11TH GEN CORE I9-11900K @ 3.50GHZ 16 27,070 433,120 Intel
9 RYZEN 9 3950X 16-CORE 32 13,163 421,216 AMD
10 RYZEN 7 5700X 8-CORE 16 26,103 417,648 AMD
11 12TH GEN CORE I7-12700K 20 20,734 414,680 Intel
12 RYZEN 9 5900X 12-CORE 24 15,401 369,624 AMD
13 RYZEN 7 5700G 16 21,671 346,736 AMD
14 RYZEN 9 3900XT 12-CORE 24 13,839 332,136 AMD
15 XEON CPU E5-2680 V4 @ 2.40GHZ 28 11,287 316,036 Intel
16 11TH GEN CORE I5-11400F @ 2.60GHZ 12 24,563 294,756 Intel
17 11TH GEN CORE I5-11600K @ 3.90GHZ 12 23,079 276,948 Intel
18 RYZEN 7 3800X 8-CORE 16 17,178 274,848 AMD
19 RYZEN 7 PRO 4750G 16 16,004 256,064 AMD
20 11TH GEN CORE I9-11900KF @ 3.50GHZ 16 15,710 251,360 Intel
21 CORE I9-7920X CPU @ 2.90GHZ 24 10,457 250,968 Intel
22 12TH GEN CORE I7-12700 20 12,518 250,360 Intel
23 CORE I7-9700K CPU @ 3.60GHZ 8 30,015 240,120 Intel
24 XEON CPU E5-2673 V3 @ 2.40GHZ 24 9,868 236,832 Intel
25 RYZEN THREADRIPPER 2950X 16-CORE 32 7,070 226,240 AMD
26 CORE I7-8700 CPU @ 3.20GHZ 12 18,819 225,828 Intel
27 RYZEN 9 5900HS 16 13,662 218,592 AMD
28 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,495 209,860 Intel
29 XEON CPU E5-2650 V2 @ 2.60GHZ 32 6,155 196,960 Intel
30 RYZEN 5 5600X 6-CORE 12 16,250 195,000 AMD
31 XEON CPU E5-2680 V3 @ 2.50GHZ 24 7,130 171,120 Intel
32 RYZEN 7 5800H 16 10,579 169,264 AMD
33 RYZEN 5 5600G 12 13,199 158,388 AMD
34 RYZEN 5 3600 6-CORE 12 12,750 153,000 AMD
35 CORE I7-7700K CPU @ 4.20GHZ 8 18,575 148,600 Intel
36 RYZEN 7 2700X EIGHT-CORE 16 9,238 147,808 AMD
37 11TH GEN CORE I5-11400 @ 2.60GHZ 12 11,782 141,384 Intel
38 RYZEN 9 3900X 12-CORE 24 5,817 139,608 AMD
39 CORE I7-10700 CPU @ 2.90GHZ 16 8,633 138,128 Intel
40 RYZEN 7 3700X 8-CORE 16 8,315 133,040 AMD
41 CORE I5-9600K CPU @ 3.70GHZ 6 19,845 119,070 Intel
42 CORE I7-10700T CPU @ 2.00GHZ 16 7,356 117,696 Intel
43 CORE I5-4278U CPU @ 2.60GHZ 4 27,842 111,368 Intel
44 12TH GEN CORE I3-12100F 8 13,907 111,256 Intel
45 CORE I7-10700K CPU @ 3.80GHZ 16 6,894 110,304 Intel
46 CORE I7-7700 CPU @ 3.60GHZ 8 13,393 107,144 Intel
47 CORE I7-6700K CPU @ 4.00GHZ 8 12,517 100,136 Intel
48 RYZEN 9 5900HX 16 6,252 100,032 AMD
49 CORE I7-4790K CPU @ 4.00GHZ 8 12,320 98,560 Intel
50 XEON CPU E5-1630 V3 @ 3.70GHZ 8 10,091 80,728 Intel
51 CORE I7-4790 CPU @ 3.60GHZ 8 9,865 78,920 Intel
52 RYZEN 7 4700U 8 9,673 77,384 AMD
53 CORE I3-8300 CPU @ 3.70GHZ 4 18,525 74,100 Intel
54 CORE I7-4770K CPU @ 3.50GHZ 8 8,973 71,784 Intel
55 CORE I7-10510U CPU @ 1.80GHZ 8 8,823 70,584 Intel
56 CORE I9-9900KF CPU @ 3.60GHZ 16 4,241 67,856 Intel
57 CORE I7-4770 CPU @ 3.40GHZ 8 8,237 65,896 Intel
58 XEON CPU E5-2698 V4 @ 2.20GHZ 16 4,111 65,776 Intel
59 CORE I5-8300H CPU @ 2.30GHZ 8 8,076 64,608 Intel
60 CORE I5-6600K CPU @ 3.50GHZ 4 16,142 64,568 Intel
61 XEON CPU E5-2680 0 @ 2.70GHZ 16 4,018 64,288 Intel
62 CORE I7-6700 CPU @ 3.40GHZ 8 7,935 63,480 Intel
63 CORE I5-6600 CPU @ 3.30GHZ 4 15,630 62,520 Intel
64 CORE I7-6700HQ CPU @ 2.60GHZ 8 7,808 62,464 Intel
65 CORE I7-4790T CPU @ 2.70GHZ 8 7,689 61,512 Intel
66 RYZEN 5 1600 SIX-CORE 12 5,123 61,476 AMD
67 CORE I9-8950HK CPU @ 2.90GHZ 12 5,091 61,092 Intel
68 CORE I5-4670K CPU @ 3.40GHZ 4 14,897 59,588 Intel
69 CORE I5-7400 CPU @ 3.00GHZ 4 14,520 58,080 Intel
70 CORE I7-3720QM CPU @ 2.60GHZ 8 7,197 57,576 Intel
71 CORE I5-4590 CPU @ 3.30GHZ 4 13,783 55,132 Intel
72 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,653 53,224 Intel
73 CORE I5-6500T CPU @ 2.50GHZ 4 13,097 52,388 Intel
74 11TH GEN CORE I5-1145G7 @ 2.60GHZ 8 6,321 50,568 Intel
75 CORE I5-4570 CPU @ 3.20GHZ 4 12,054 48,216 Intel
76 CORE I5-8250U CPU @ 1.60GHZ 8 5,911 47,288 Intel
77 CORE I7-4770HQ CPU @ 2.20GHZ 8 5,796 46,368 Intel
78 XEON CPU E3-1240 V2 @ 3.40GHZ 8 5,203 41,624 Intel
79 RYZEN 3 3200G 4 10,242 40,968 AMD
80 CORE I7 CPU 975 @ 3.33GHZ 8 4,988 39,904 Intel
81 CORE I5-6500 CPU @ 3.20GHZ 4 9,841 39,364 Intel
82 PENTIUM(R) CPU G4560 @ 3.50GHZ 4 9,714 38,856 Intel
83 XEON CPU E3-1220 V2 @ 3.10GHZ 4 9,622 38,488 Intel
84 CORE I5-3570 CPU @ 3.40GHZ 4 9,015 36,060 Intel
85 XEON CPU E5-2697 V2 @ 2.70GHZ 24 1,487 35,688 Intel
86 CORE I5-10400 CPU @ 2.90GHZ 12 2,928 35,136 Intel
87 CORE I5-8265U CPU @ 1.60GHZ 8 4,041 32,328 Intel
88 CORE I3-4170 CPU @ 3.70GHZ 4 7,787 31,148 Intel
89 RYZEN 5 PRO 2400G 8 3,869 30,952 AMD
90 XEON CPU E31245 @ 3.30GHZ 8 3,414 27,312 Intel
91 XEON CPU E3-1245 V2 @ 3.40GHZ 8 3,401 27,208 Intel
92 XEON CPU E5-2620 0 @ 2.00GHZ 12 2,151 25,812 Intel
93 FX-8150 EIGHT-CORE 8 2,636 21,088 AMD
94 CORE I7-8550U CPU @ 1.80GHZ 8 2,480 19,840 Intel
95 XEON CPU E5-2690 V2 @ 3.00GHZ 20 959 19,180 Intel
96 CORE I5-3470 CPU @ 3.20GHZ 4 4,721 18,884 Intel
97 CORE I5-5200U CPU @ 2.20GHZ 4 4,574 18,296 Intel
98 CORE I3-2120 CPU @ 3.30GHZ 4 3,148 12,592 Intel
99 CORE I3-6006U CPU @ 2.00GHZ 4 3,059 12,236 Intel
100 CORE I3-3225 CPU @ 3.30GHZ 4 2,917 11,668 Intel
101 CORE I3-3240 CPU @ 3.40GHZ 4 2,803 11,212 Intel
102 CORE I3-3220 CPU @ 3.30GHZ 4 2,731 10,924 Intel
103 CORE I5 CPU 750 @ 2.67GHZ 4 2,410 9,640 Intel
104 CORE I3-1000NG4 CPU @ 1.10GHZ 4 1,369 5,476 Intel
105 CORE I5-7200U CPU @ 2.50GHZ 4 1,091 4,364 Intel
106 A12-9800 RADEON R7, 12 COMPUTE CORES 4C+8G 4 871 3,484 AMD
107 CELERON(R) J4125 CPU @ 2.00GHZ 4 694 2,776 Intel
108 PRO A10-9700 R7, 10 COMPUTE CORES 4C+6G 4 497 1,988 AMD
109 FX-4300 QUAD-CORE 4 364 1,456 AMD
110 A8-6410 APU 4 117 468 AMD