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PROJECT #16995 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These projects aim to simulate the dynamics of a large number of designed mini-proteins (< 50 residues), to establish the ability of molecular simulations to accurately predict thermodynamic and kinetic effects of designed mutations.

We aim to develop a library of experimental and simulation data so we can compare the performance of different techniques for computational protein design, such as adaptive sampling.

Prediction and design of mini-protein structure and dynamics is highly relevant to developing new biotherapeutics for a wide range of human diseases. Projects 16935, 16958, and 16995 are chignolin, a small designed hairpin peptide..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 12,120

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 02 October 2022 12:16:37

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 02 October 2022 12:16:37

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 5900X 12-CORE 24 24,802 595,248 AMD
2 RYZEN 9 3900 12-CORE 24 21,648 519,552 AMD
3 RYZEN 9 5950X 16-CORE 32 15,560 497,920 AMD
4 RYZEN 7 5800X 8-CORE 16 31,089 497,424 AMD
5 EPYC 7V12 64-CORE 64 7,256 464,384 AMD
6 RYZEN 7 5800X3D 8-CORE 16 28,557 456,912 AMD
7 11TH GEN CORE I7-11700K @ 3.60GHZ 16 27,253 436,048 Intel
8 11TH GEN CORE I9-11900K @ 3.50GHZ 16 26,975 431,600 Intel
9 RYZEN 9 3950X 16-CORE 32 13,329 426,528 AMD
10 12TH GEN CORE I9-12900K 24 17,626 423,024 Intel
11 12TH GEN CORE I7-12700K 20 19,946 398,920 Intel
12 CORE I9-10850K CPU @ 3.60GHZ 20 19,120 382,400 Intel
13 RYZEN 7 5700X 8-CORE 16 23,652 378,432 AMD
14 RYZEN 9 3900XT 12-CORE 24 13,741 329,784 AMD
15 XEON CPU E5-2680 V4 @ 2.40GHZ 28 11,287 316,036 Intel
16 CORE I9-10900X CPU @ 3.70GHZ 20 15,340 306,800 Intel
17 RYZEN 7 5700G 16 18,559 296,944 AMD
18 11TH GEN CORE I5-11400F @ 2.60GHZ 12 24,563 294,756 Intel
19 11TH GEN CORE I5-11600K @ 3.90GHZ 12 23,079 276,948 Intel
20 RYZEN 7 3800X 8-CORE 16 17,005 272,080 AMD
21 12TH GEN CORE I5-12600K 16 16,127 258,032 Intel
22 XEON CPU E5-2680 V2 @ 2.80GHZ 40 6,345 253,800 Intel
23 11TH GEN CORE I9-11900KF @ 3.50GHZ 16 15,710 251,360 Intel
24 CORE I9-7920X CPU @ 2.90GHZ 24 10,457 250,968 Intel
25 12TH GEN CORE I7-12700 20 12,518 250,360 Intel
26 RYZEN 7 PRO 4750G 16 15,571 249,136 AMD
27 XEON CPU E5-2673 V3 @ 2.40GHZ 24 9,868 236,832 Intel
28 RYZEN THREADRIPPER 2950X 16-CORE 32 7,070 226,240 AMD
29 CORE I7-8700 CPU @ 3.20GHZ 12 18,556 222,672 Intel
30 RYZEN 9 5900HS 16 13,662 218,592 AMD
31 CORE I7-9700K CPU @ 3.60GHZ 8 26,903 215,224 Intel
32 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,495 209,860 Intel
33 RYZEN 5 5600G 12 16,726 200,712 AMD
34 XEON CPU E5-2650 V2 @ 2.60GHZ 32 6,155 196,960 Intel
35 RYZEN 5 5600X 6-CORE 12 14,976 179,712 AMD
36 XEON CPU E5-2680 V3 @ 2.50GHZ 24 7,130 171,120 Intel
37 RYZEN 7 5800H 16 10,579 169,264 AMD
38 CORE I5-8500 CPU @ 3.00GHZ 6 27,324 163,944 Intel
39 RYZEN 5 3600 6-CORE 12 12,590 151,080 AMD
40 XEON GOLD 6128 CPU @ 3.40GHZ 12 11,646 139,752 Intel
41 CORE I7-7700K CPU @ 4.20GHZ 8 17,453 139,624 Intel
42 RYZEN 7 2700X EIGHT-CORE 16 8,726 139,616 AMD
43 CORE I7-10700 CPU @ 2.90GHZ 16 8,633 138,128 Intel
44 APPLE M1 MAX 10 13,715 137,150 Apple
45 RYZEN 9 3900X 12-CORE 24 5,637 135,288 AMD
46 11TH GEN CORE I5-11400 @ 2.60GHZ 12 11,266 135,192 Intel
47 RYZEN 7 4800H 16 8,203 131,248 AMD
48 RYZEN 7 3700X 8-CORE 16 8,089 129,424 AMD
49 CORE I7-10700T CPU @ 2.00GHZ 16 7,582 121,312 Intel
50 CORE I5-9600K CPU @ 3.70GHZ 6 19,845 119,070 Intel
51 CORE I5-4278U CPU @ 2.60GHZ 4 27,842 111,368 Intel
52 12TH GEN CORE I3-12100F 8 13,907 111,256 Intel
53 CORE I7-10700K CPU @ 3.80GHZ 16 6,894 110,304 Intel
54 CORE I7-7700 CPU @ 3.60GHZ 8 13,393 107,144 Intel
55 XEON CPU E5-2698 V4 @ 2.20GHZ 16 6,416 102,656 Intel
56 CORE I7-6700K CPU @ 4.00GHZ 8 12,517 100,136 Intel
57 RYZEN 9 5900HX 16 6,252 100,032 AMD
58 CORE I7-4790K CPU @ 4.00GHZ 8 12,320 98,560 Intel
59 12TH GEN CORE I7-12700H 20 4,619 92,380 Intel
60 XEON CPU E3-1270 V5 @ 3.60GHZ 8 11,496 91,968 Intel
61 XEON CPU E5-1630 V3 @ 3.70GHZ 8 10,091 80,728 Intel
62 CORE I7-4790 CPU @ 3.60GHZ 8 9,865 78,920 Intel
63 RYZEN 7 4700U 8 9,673 77,384 AMD
64 11TH GEN CORE I7-1185G7 @ 3.00GHZ 8 9,305 74,440 Intel
65 CORE I3-8300 CPU @ 3.70GHZ 4 18,525 74,100 Intel
66 CORE I7-4770K CPU @ 3.50GHZ 8 8,973 71,784 Intel
67 CORE I7-10510U CPU @ 1.80GHZ 8 8,823 70,584 Intel
68 CORE I9-9900KF CPU @ 3.60GHZ 16 4,241 67,856 Intel
69 CORE I7-4770 CPU @ 3.40GHZ 8 8,237 65,896 Intel
70 CORE I5-6600K CPU @ 3.50GHZ 4 16,330 65,320 Intel
71 CORE I5-8300H CPU @ 2.30GHZ 8 8,076 64,608 Intel
72 CORE I9-8950HK CPU @ 2.90GHZ 12 5,351 64,212 Intel
73 CORE I7-6700 CPU @ 3.40GHZ 8 7,935 63,480 Intel
74 XEON CPU E5-2680 0 @ 2.70GHZ 16 3,938 63,008 Intel
75 CORE I5-4690 CPU @ 3.50GHZ 4 15,745 62,980 Intel
76 CORE I5-6600 CPU @ 3.30GHZ 4 15,630 62,520 Intel
77 CORE I7-6700HQ CPU @ 2.60GHZ 8 7,808 62,464 Intel
78 CORE I7-4790T CPU @ 2.70GHZ 8 7,689 61,512 Intel
79 RYZEN 5 1600 SIX-CORE 12 5,123 61,476 AMD
80 CORE I5-4670K CPU @ 3.40GHZ 4 14,897 59,588 Intel
81 CORE I7-3720QM CPU @ 2.60GHZ 8 7,197 57,576 Intel
82 CORE I5-7400 CPU @ 3.00GHZ 4 14,329 57,316 Intel
83 CORE I5-9300H CPU @ 2.40GHZ 8 6,793 54,344 Intel
84 XEON CPU E5-2697 V2 @ 2.70GHZ 24 2,251 54,024 Intel
85 CORE I5-4590 CPU @ 3.30GHZ 4 13,362 53,448 Intel
86 CORE I5-6500T CPU @ 2.50GHZ 4 13,097 52,388 Intel
87 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,538 52,304 Intel
88 11TH GEN CORE I5-1145G7 @ 2.60GHZ 8 6,321 50,568 Intel
89 CORE I5-8600T CPU @ 2.30GHZ 6 8,126 48,756 Intel
90 CORE I5-8250U CPU @ 1.60GHZ 8 5,911 47,288 Intel
91 CORE I7-4770HQ CPU @ 2.20GHZ 8 5,874 46,992 Intel
92 APPLE M1 8 5,348 42,784 Apple
93 CORE I5-4570 CPU @ 3.20GHZ 4 10,568 42,272 Intel
94 XEON CPU E3-1240 V2 @ 3.40GHZ 8 5,203 41,624 Intel
95 RYZEN 3 3200G 4 10,242 40,968 AMD
96 CORE I7 CPU 975 @ 3.33GHZ 8 4,988 39,904 Intel
97 CORE I5-3570K CPU @ 3.40GHZ 4 9,913 39,652 Intel
98 CORE I5-6500 CPU @ 3.20GHZ 4 9,841 39,364 Intel
99 PENTIUM(R) CPU G4560 @ 3.50GHZ 4 9,714 38,856 Intel
100 XEON CPU E3-1220 V2 @ 3.10GHZ 4 9,622 38,488 Intel
101 CORE I5-8350U CPU @ 1.70GHZ 8 4,646 37,168 Intel
102 CORE I5-3570 CPU @ 3.40GHZ 4 9,015 36,060 Intel
103 CORE I5-10400 CPU @ 2.90GHZ 12 2,928 35,136 Intel
104 CORE I5-8265U CPU @ 1.60GHZ 8 4,041 32,328 Intel
105 CORE I3-4170 CPU @ 3.70GHZ 4 7,787 31,148 Intel
106 RYZEN 5 PRO 2400G 8 3,869 30,952 AMD
107 APPLE M1 PRO 10 3,049 30,490 Apple
108 XEON CPU E31245 @ 3.30GHZ 8 3,414 27,312 Intel
109 XEON CPU E3-1245 V2 @ 3.40GHZ 8 3,401 27,208 Intel
110 CORE I7-3770K CPU @ 3.50GHZ 8 3,294 26,352 Intel
111 XEON CPU E5-2620 0 @ 2.00GHZ 12 2,151 25,812 Intel
112 FX-8150 EIGHT-CORE 8 2,636 21,088 AMD
113 XEON CPU E5-2650L V4 @ 1.70GHZ 28 744 20,832 Intel
114 CORE I7-8550U CPU @ 1.80GHZ 8 2,480 19,840 Intel
115 XEON CPU E5-2690 V2 @ 3.00GHZ 20 959 19,180 Intel
116 CORE I5-3470 CPU @ 3.20GHZ 4 4,721 18,884 Intel
117 CORE I5-5200U CPU @ 2.20GHZ 4 4,574 18,296 Intel
118 CORE I3-2120 CPU @ 3.30GHZ 4 3,148 12,592 Intel
119 CORE I3-6006U CPU @ 2.00GHZ 4 2,946 11,784 Intel
120 CORE I3-3225 CPU @ 3.30GHZ 4 2,917 11,668 Intel
121 CORE I3-3240 CPU @ 3.40GHZ 4 2,803 11,212 Intel
122 CORE I3-3220 CPU @ 3.30GHZ 4 2,731 10,924 Intel
123 CORE I5 CPU 750 @ 2.67GHZ 4 2,410 9,640 Intel
124 CORE I3-1000NG4 CPU @ 1.10GHZ 4 1,369 5,476 Intel
125 CORE I5-7200U CPU @ 2.50GHZ 4 1,091 4,364 Intel
126 A12-9800 RADEON R7, 12 COMPUTE CORES 4C+8G 4 871 3,484 AMD
127 CELERON(R) J4125 CPU @ 2.00GHZ 4 694 2,776 Intel
128 PRO A10-9700 R7, 10 COMPUTE CORES 4C+6G 4 497 1,988 AMD
129 FX-4300 QUAD-CORE 4 364 1,456 AMD
130 A8-6410 APU 4 117 468 AMD