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Research: CANCER Folding Project #16995

Project #16995 overview

Project Summary AI Beta

This project uses computer simulations to study mini-proteins (tiny proteins). They want to see how well computers can predict how changes to these proteins affect their shape and function. This research could lead to new medicines for diseases.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Prof. Vincent Voelz
Institution
Temple University

Work unit

Atoms
12,120
Core
0xa8
Status
Public
Source material

Official Project Description

These projects aim to simulate the dynamics of a large number of designed mini-proteins (< 50 residues), to establish the ability of molecular simulations to accurately predict thermodynamic and kinetic effects of designed mutations.

We aim to develop a library of experimental and simulation data so we can compare the performance of different techniques for computational protein design, such as adaptive sampling.

Prediction and design of mini-protein structure and dynamics is highly relevant to developing new biotherapeutics for a wide range of human diseases. Projects 16935, 16958, and 16995 are chignolin, a small designed hairpin peptide.

Performance data

Hardware Performance for Project 16995

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:00:19

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 7 7700X 8-CORE 16 34,762 556,192 AMD
2 RYZEN 9 5950X 16-CORE 32 16,327 522,464 AMD
3 RYZEN 9 3900 12-CORE 24 21,648 519,552 AMD
4 RYZEN 7 5800X3D 8-CORE 16 32,446 519,136 AMD
5 RYZEN 9 5900X 12-CORE 24 21,529 516,696 AMD
6 RYZEN 7 5800X 8-CORE 16 30,901 494,416 AMD
7 EPYC 7V12 64-CORE 64 7,256 464,384 AMD
8 11TH GEN CORE I7-11700K @ 3.60GHZ 16 27,253 436,048 Intel
9 11TH GEN CORE I9-11900K @ 3.50GHZ 16 26,975 431,600 Intel
10 12TH GEN CORE I9-12900K 24 17,626 423,024 Intel
11 RYZEN 9 3950X 16-CORE 32 12,746 407,872 AMD
12 12TH GEN CORE I7-12700K 20 19,965 399,300 Intel
13 RYZEN 7 5700G 16 22,930 366,880 AMD
14 CORE I9-10850K CPU @ 3.60GHZ 20 17,313 346,260 Intel
15 CORE I9-10900X CPU @ 3.70GHZ 20 16,505 330,100 Intel
16 RYZEN 9 3900XT 12-CORE 24 13,725 329,400 AMD
17 XEON CPU E5-2680 V4 @ 2.40GHZ 28 11,287 316,036 Intel
18 11TH GEN CORE I5-11400F @ 2.60GHZ 12 24,563 294,756 Intel
19 RYZEN 7 5700X 8-CORE 16 18,138 290,208 AMD
20 11TH GEN CORE I5-11600K @ 3.90GHZ 12 23,079 276,948 Intel
21 RYZEN 7 3800X 8-CORE 16 17,051 272,816 AMD
22 11TH GEN CORE I9-11900KF @ 3.50GHZ 16 15,710 251,360 Intel
23 CORE I9-7920X CPU @ 2.90GHZ 24 10,457 250,968 Intel
24 12TH GEN CORE I7-12700 20 12,518 250,360 Intel
25 RYZEN 9 3900X 12-CORE 24 10,210 245,040 AMD
26 12TH GEN CORE I5-12400 12 20,081 240,972 Intel
27 RYZEN 7 PRO 4750G 16 14,933 238,928 AMD
28 12TH GEN CORE I5-12600K 16 14,876 238,016 Intel
29 XEON CPU E5-2673 V3 @ 2.40GHZ 24 9,868 236,832 Intel
30 XEON CPU E5-2680 V2 @ 2.80GHZ 40 5,757 230,280 Intel
31 RYZEN THREADRIPPER 2950X 16-CORE 32 7,070 226,240 AMD
32 RYZEN 9 5900HS 16 13,662 218,592 AMD
33 CORE I7-8700 CPU @ 3.20GHZ 12 18,001 216,012 Intel
34 CORE I7-9700K CPU @ 3.60GHZ 8 26,949 215,592 Intel
35 RYZEN 3 3300X 4-CORE 8 26,326 210,608 AMD
36 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,495 209,860 Intel
37 CORE I5-8600K CPU @ 3.60GHZ 6 34,746 208,476 Intel
38 RYZEN 5 5600G 12 16,726 200,712 AMD
39 CORE I7-9700 CPU @ 3.00GHZ 8 23,610 188,880 Intel
40 RYZEN 5 5600X 6-CORE 12 15,604 187,248 AMD
41 XEON CPU E5-2650 V2 @ 2.60GHZ 32 5,799 185,568 Intel
42 RYZEN 7 5800H 16 10,974 175,584 AMD
43 XEON CPU E5-2680 V3 @ 2.50GHZ 24 7,130 171,120 Intel
44 CORE I5-8500 CPU @ 3.00GHZ 6 27,324 163,944 Intel
45 RYZEN 5 3600 6-CORE 12 12,786 153,432 AMD
46 XEON GOLD 6128 CPU @ 3.40GHZ 12 11,646 139,752 Intel
47 CORE I7-7700K CPU @ 4.20GHZ 8 17,455 139,640 Intel
48 CORE I7-10700 CPU @ 2.90GHZ 16 8,633 138,128 Intel
49 CORE I5-10400 CPU @ 2.90GHZ 12 11,192 134,304 Intel
50 CORE I7-10700K CPU @ 3.80GHZ 16 8,383 134,128 Intel
51 RYZEN 7 4800H 16 8,203 131,248 AMD
52 CORE I7-5820K CPU @ 3.30GHZ 12 10,922 131,064 Intel
53 RYZEN 7 3700X 8-CORE 16 8,089 129,424 AMD
54 11TH GEN CORE I5-11400 @ 2.60GHZ 12 10,577 126,924 Intel
55 APPLE M1 MAX 10 12,614 126,140 Apple
56 CORE I7-10700T CPU @ 2.00GHZ 16 7,582 121,312 Intel
57 CORE I5-9600K CPU @ 3.70GHZ 6 19,845 119,070 Intel
58 RYZEN 7 2700X EIGHT-CORE 16 7,350 117,600 AMD
59 12TH GEN CORE I3-12100F 8 13,907 111,256 Intel
60 CORE I7-6700K CPU @ 4.00GHZ 8 13,405 107,240 Intel
61 CORE I7-7700 CPU @ 3.60GHZ 8 13,393 107,144 Intel
62 RYZEN THREADRIPPER 1920X 12-CORE 24 4,417 106,008 AMD
63 12TH GEN CORE I9-12900H 20 5,292 105,840 Intel
64 RYZEN 9 4900HS 16 6,456 103,296 AMD
65 XEON CPU E5-2698 V4 @ 2.20GHZ 16 6,416 102,656 Intel
66 RYZEN 9 5900HX 16 6,252 100,032 AMD
67 CORE I7-4790K CPU @ 4.00GHZ 8 12,212 97,696 Intel
68 CORE I7-4980HQ CPU @ 2.80GHZ 8 12,058 96,464 Intel
69 CORE I7-9750H CPU @ 2.60GHZ 12 8,030 96,360 Intel
70 CORE I7-8705G CPU @ 3.10GHZ 8 11,869 94,952 Intel
71 XEON CPU E3-1270 V5 @ 3.60GHZ 8 11,606 92,848 Intel
72 12TH GEN CORE I7-12700H 20 4,619 92,380 Intel
73 13TH GEN CORE I9-13900K 32 2,862 91,584 Intel
74 XEON CPU E5-2697 V2 @ 2.70GHZ 24 3,683 88,392 Intel
75 XEON CPU E5-1630 V3 @ 3.70GHZ 8 10,091 80,728 Intel
76 CORE I7-4790 CPU @ 3.60GHZ 8 9,865 78,920 Intel
77 RYZEN 7 4700U 8 9,673 77,384 AMD
78 CORE I5-7500 CPU @ 3.40GHZ 4 19,133 76,532 Intel
79 RYZEN 5 2600X SIX-CORE 12 6,237 74,844 AMD
80 11TH GEN CORE I7-1185G7 @ 3.00GHZ 8 9,305 74,440 Intel
81 CORE I3-8300 CPU @ 3.70GHZ 4 18,525 74,100 Intel
82 CORE I7-4770K CPU @ 3.50GHZ 8 9,231 73,848 Intel
83 CORE I7-10510U CPU @ 1.80GHZ 8 8,823 70,584 Intel
84 CORE I9-9900KF CPU @ 3.60GHZ 16 4,241 67,856 Intel
85 CORE I7-4770 CPU @ 3.40GHZ 8 8,237 65,896 Intel
86 CORE I9-8950HK CPU @ 2.90GHZ 12 5,466 65,592 Intel
87 CORE I5-6600K CPU @ 3.50GHZ 4 16,330 65,320 Intel
88 CORE I5-8300H CPU @ 2.30GHZ 8 8,076 64,608 Intel
89 CORE I7-6700 CPU @ 3.40GHZ 8 7,935 63,480 Intel
90 XEON CPU E5-2680 0 @ 2.70GHZ 16 3,863 61,808 Intel
91 CORE I7-4790T CPU @ 2.70GHZ 8 7,689 61,512 Intel
92 RYZEN 5 1600 SIX-CORE 12 5,123 61,476 AMD
93 CORE I5-6500 CPU @ 3.20GHZ 4 15,051 60,204 Intel
94 CORE I5-4690 CPU @ 3.50GHZ 4 15,039 60,156 Intel
95 CORE I5-4670K CPU @ 3.40GHZ 4 14,897 59,588 Intel
96 CORE I7-6700HQ CPU @ 2.60GHZ 8 7,131 57,048 Intel
97 CORE I5-7400 CPU @ 3.00GHZ 4 14,227 56,908 Intel
98 CORE I7-3720QM CPU @ 2.60GHZ 8 7,001 56,008 Intel
99 CORE I5-9300H CPU @ 2.40GHZ 8 6,793 54,344 Intel
100 CORE I5-6500T CPU @ 2.50GHZ 4 13,144 52,576 Intel
101 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,538 52,304 Intel
102 CORE I5-4590 CPU @ 3.30GHZ 4 12,912 51,648 Intel
103 11TH GEN CORE I5-1145G7 @ 2.60GHZ 8 6,321 50,568 Intel
104 CORE I5-8600T CPU @ 2.30GHZ 6 8,126 48,756 Intel
105 CORE I5-2500K CPU @ 3.30GHZ 4 12,063 48,252 Intel
106 CORE I5-8250U CPU @ 1.60GHZ 8 5,911 47,288 Intel
107 CORE I7-4770HQ CPU @ 2.20GHZ 8 5,874 46,992 Intel
108 CORE I5-4570 CPU @ 3.20GHZ 4 10,568 42,272 Intel
109 XEON CPU E3-1240 V2 @ 3.40GHZ 8 5,125 41,000 Intel
110 RYZEN 3 3200G 4 10,242 40,968 AMD
111 APPLE M1 8 5,058 40,464 Apple
112 CORE I5-3570K CPU @ 3.40GHZ 4 9,913 39,652 Intel
113 CORE I5-6600 CPU @ 3.30GHZ 4 9,632 38,528 Intel
114 XEON CPU E3-1220 V2 @ 3.10GHZ 4 9,622 38,488 Intel
115 CORE I5-8350U CPU @ 1.70GHZ 8 4,646 37,168 Intel
116 CORE I5-3570 CPU @ 3.40GHZ 4 9,015 36,060 Intel
117 CORE I5-8265U CPU @ 1.60GHZ 8 4,041 32,328 Intel
118 CORE I3-4170 CPU @ 3.70GHZ 4 7,787 31,148 Intel
119 CORE I7 CPU 975 @ 3.33GHZ 8 3,878 31,024 Intel
120 RYZEN 5 PRO 2400G 8 3,869 30,952 AMD
121 APPLE M1 PRO 10 3,049 30,490 Apple
122 XEON CPU E31245 @ 3.30GHZ 8 3,414 27,312 Intel
123 XEON CPU E3-1245 V2 @ 3.40GHZ 8 3,401 27,208 Intel
124 CORE I7-3770K CPU @ 3.50GHZ 8 3,294 26,352 Intel
125 XEON CPU E5-2620 0 @ 2.00GHZ 12 2,151 25,812 Intel
126 RYZEN 5 2400G 8 2,814 22,512 AMD
127 FX-8150 EIGHT-CORE 8 2,636 21,088 AMD
128 XEON CPU E5-2650L V4 @ 1.70GHZ 28 744 20,832 Intel
129 CORE I7-8550U CPU @ 1.80GHZ 8 2,480 19,840 Intel
130 XEON CPU E5-2690 V2 @ 3.00GHZ 20 959 19,180 Intel
131 RYZEN 7 3700U 8 2,369 18,952 AMD
132 CORE I5-3470 CPU @ 3.20GHZ 4 4,721 18,884 Intel
133 CORE I5-5200U CPU @ 2.20GHZ 4 4,574 18,296 Intel
134 CORE I7-3667U CPU @ 2.00GHZ 4 3,884 15,536 Intel
135 CORE I5-4300U CPU @ 1.90GHZ 4 3,857 15,428 Intel
136 PENTIUM(R) CPU G4560 @ 3.50GHZ 4 3,354 13,416 Intel
137 CORE I3-2120 CPU @ 3.30GHZ 4 3,148 12,592 Intel
138 CORE I3-6006U CPU @ 2.00GHZ 4 2,975 11,900 Intel
139 CORE I3-3225 CPU @ 3.30GHZ 4 2,917 11,668 Intel
140 CORE I3-3240 CPU @ 3.40GHZ 4 2,803 11,212 Intel
141 CORE I3-3220 CPU @ 3.30GHZ 4 2,739 10,956 Intel
142 CORE I5 CPU 750 @ 2.67GHZ 4 2,410 9,640 Intel
143 CORE I3-3110M CPU @ 2.40GHZ 4 1,691 6,764 Intel
144 CORE I3-1000NG4 CPU @ 1.10GHZ 4 1,369 5,476 Intel
145 CORE I5-7200U CPU @ 2.50GHZ 4 1,091 4,364 Intel
146 A12-9800 RADEON R7, 12 COMPUTE CORES 4C+8G 4 871 3,484 AMD
147 CELERON(R) J4125 CPU @ 2.00GHZ 4 694 2,776 Intel
148 PRO A10-9700 R7, 10 COMPUTE CORES 4C+6G 4 497 1,988 AMD
149 FX-4300 QUAD-CORE 4 364 1,456 AMD
150 A8-6410 APU 4 117 468 AMD