1. Projects
  2. Research Project Folding Profile

PROJECT #16995 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These projects aim to simulate the dynamics of a large number of designed mini-proteins (< 50 residues), to establish the ability of molecular simulations to accurately predict thermodynamic and kinetic effects of designed mutations.

We aim to develop a library of experimental and simulation data so we can compare the performance of different techniques for computational protein design, such as adaptive sampling.

Prediction and design of mini-protein structure and dynamics is highly relevant to developing new biotherapeutics for a wide range of human diseases. Projects 16935, 16958, and 16995 are chignolin, a small designed hairpin peptide..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 12,120

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Tuesday, 07 February 2023 06:14:54

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Tuesday, 07 February 2023 06:14:54

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 7 7700X 8-CORE 16 34,762 556,192 AMD
2 RYZEN 9 5950X 16-CORE 32 16,327 522,464 AMD
3 RYZEN 9 3900 12-CORE 24 21,648 519,552 AMD
4 RYZEN 7 5800X3D 8-CORE 16 32,446 519,136 AMD
5 RYZEN 9 5900X 12-CORE 24 21,529 516,696 AMD
6 RYZEN 7 5800X 8-CORE 16 30,901 494,416 AMD
7 EPYC 7V12 64-CORE 64 7,256 464,384 AMD
8 11TH GEN CORE I7-11700K @ 3.60GHZ 16 27,253 436,048 Intel
9 11TH GEN CORE I9-11900K @ 3.50GHZ 16 26,975 431,600 Intel
10 12TH GEN CORE I9-12900K 24 17,626 423,024 Intel
11 RYZEN 9 3950X 16-CORE 32 12,746 407,872 AMD
12 12TH GEN CORE I7-12700K 20 19,965 399,300 Intel
13 RYZEN 7 5700G 16 22,930 366,880 AMD
14 CORE I9-10850K CPU @ 3.60GHZ 20 17,313 346,260 Intel
15 CORE I9-10900X CPU @ 3.70GHZ 20 16,505 330,100 Intel
16 RYZEN 9 3900XT 12-CORE 24 13,725 329,400 AMD
17 XEON CPU E5-2680 V4 @ 2.40GHZ 28 11,287 316,036 Intel
18 11TH GEN CORE I5-11400F @ 2.60GHZ 12 24,563 294,756 Intel
19 RYZEN 7 5700X 8-CORE 16 18,138 290,208 AMD
20 11TH GEN CORE I5-11600K @ 3.90GHZ 12 23,079 276,948 Intel
21 RYZEN 7 3800X 8-CORE 16 17,051 272,816 AMD
22 12TH GEN CORE I5-12600K 16 16,127 258,032 Intel
23 11TH GEN CORE I9-11900KF @ 3.50GHZ 16 15,710 251,360 Intel
24 CORE I9-7920X CPU @ 2.90GHZ 24 10,457 250,968 Intel
25 12TH GEN CORE I7-12700 20 12,518 250,360 Intel
26 RYZEN 9 3900X 12-CORE 24 10,210 245,040 AMD
27 12TH GEN CORE I5-12400 12 20,081 240,972 Intel
28 RYZEN 7 PRO 4750G 16 14,933 238,928 AMD
29 XEON CPU E5-2673 V3 @ 2.40GHZ 24 9,868 236,832 Intel
30 XEON CPU E5-2680 V2 @ 2.80GHZ 40 5,757 230,280 Intel
31 RYZEN THREADRIPPER 2950X 16-CORE 32 7,070 226,240 AMD
32 RYZEN 9 5900HS 16 13,662 218,592 AMD
33 CORE I7-8700 CPU @ 3.20GHZ 12 18,001 216,012 Intel
34 CORE I7-9700K CPU @ 3.60GHZ 8 26,949 215,592 Intel
35 RYZEN 3 3300X 4-CORE 8 26,326 210,608 AMD
36 XEON CPU E5-2690 V4 @ 2.60GHZ 28 7,495 209,860 Intel
37 CORE I5-8600K CPU @ 3.60GHZ 6 34,746 208,476 Intel
38 RYZEN 5 5600G 12 16,726 200,712 AMD
39 CORE I7-9700 CPU @ 3.00GHZ 8 23,610 188,880 Intel
40 RYZEN 5 5600X 6-CORE 12 15,604 187,248 AMD
41 XEON CPU E5-2650 V2 @ 2.60GHZ 32 5,799 185,568 Intel
42 RYZEN 7 5800H 16 10,974 175,584 AMD
43 XEON CPU E5-2680 V3 @ 2.50GHZ 24 7,130 171,120 Intel
44 CORE I5-8500 CPU @ 3.00GHZ 6 27,324 163,944 Intel
45 RYZEN 5 3600 6-CORE 12 12,786 153,432 AMD
46 XEON GOLD 6128 CPU @ 3.40GHZ 12 11,646 139,752 Intel
47 CORE I7-7700K CPU @ 4.20GHZ 8 17,455 139,640 Intel
48 CORE I7-10700 CPU @ 2.90GHZ 16 8,633 138,128 Intel
49 11TH GEN CORE I5-11400 @ 2.60GHZ 12 11,266 135,192 Intel
50 CORE I5-10400 CPU @ 2.90GHZ 12 11,192 134,304 Intel
51 CORE I7-10700K CPU @ 3.80GHZ 16 8,383 134,128 Intel
52 RYZEN 7 4800H 16 8,203 131,248 AMD
53 CORE I7-5820K CPU @ 3.30GHZ 12 10,922 131,064 Intel
54 RYZEN 7 3700X 8-CORE 16 8,089 129,424 AMD
55 APPLE M1 MAX 10 12,614 126,140 Apple
56 CORE I7-10700T CPU @ 2.00GHZ 16 7,582 121,312 Intel
57 CORE I5-9600K CPU @ 3.70GHZ 6 19,845 119,070 Intel
58 RYZEN 7 2700X EIGHT-CORE 16 7,350 117,600 AMD
59 CORE I5-4278U CPU @ 2.60GHZ 4 27,842 111,368 Intel
60 12TH GEN CORE I3-12100F 8 13,907 111,256 Intel
61 CORE I7-6700K CPU @ 4.00GHZ 8 13,405 107,240 Intel
62 CORE I7-7700 CPU @ 3.60GHZ 8 13,393 107,144 Intel
63 RYZEN THREADRIPPER 1920X 12-CORE 24 4,417 106,008 AMD
64 12TH GEN CORE I9-12900H 20 5,292 105,840 Intel
65 RYZEN 9 4900HS 16 6,456 103,296 AMD
66 XEON CPU E5-2698 V4 @ 2.20GHZ 16 6,416 102,656 Intel
67 RYZEN 9 5900HX 16 6,252 100,032 AMD
68 CORE I7-4790K CPU @ 4.00GHZ 8 12,252 98,016 Intel
69 CORE I7-4980HQ CPU @ 2.80GHZ 8 12,058 96,464 Intel
70 CORE I7-9750H CPU @ 2.60GHZ 12 8,030 96,360 Intel
71 CORE I7-8705G CPU @ 3.10GHZ 8 11,869 94,952 Intel
72 XEON CPU E3-1270 V5 @ 3.60GHZ 8 11,606 92,848 Intel
73 12TH GEN CORE I7-12700H 20 4,619 92,380 Intel
74 13TH GEN CORE I9-13900K 32 2,862 91,584 Intel
75 XEON CPU E5-2697 V2 @ 2.70GHZ 24 3,683 88,392 Intel
76 XEON CPU E5-1630 V3 @ 3.70GHZ 8 10,091 80,728 Intel
77 CORE I7-4790 CPU @ 3.60GHZ 8 9,865 78,920 Intel
78 RYZEN 7 4700U 8 9,673 77,384 AMD
79 CORE I5-7500 CPU @ 3.40GHZ 4 19,133 76,532 Intel
80 RYZEN 5 2600X SIX-CORE 12 6,237 74,844 AMD
81 11TH GEN CORE I7-1185G7 @ 3.00GHZ 8 9,305 74,440 Intel
82 CORE I3-8300 CPU @ 3.70GHZ 4 18,525 74,100 Intel
83 CORE I7-4770K CPU @ 3.50GHZ 8 9,231 73,848 Intel
84 CORE I7-10510U CPU @ 1.80GHZ 8 8,823 70,584 Intel
85 CORE I9-9900KF CPU @ 3.60GHZ 16 4,241 67,856 Intel
86 CORE I7-4770 CPU @ 3.40GHZ 8 8,237 65,896 Intel
87 CORE I9-8950HK CPU @ 2.90GHZ 12 5,466 65,592 Intel
88 CORE I5-6600K CPU @ 3.50GHZ 4 16,330 65,320 Intel
89 CORE I5-8300H CPU @ 2.30GHZ 8 8,076 64,608 Intel
90 CORE I7-6700 CPU @ 3.40GHZ 8 7,935 63,480 Intel
91 CORE I7-6700HQ CPU @ 2.60GHZ 8 7,808 62,464 Intel
92 XEON CPU E5-2680 0 @ 2.70GHZ 16 3,863 61,808 Intel
93 CORE I7-4790T CPU @ 2.70GHZ 8 7,689 61,512 Intel
94 RYZEN 5 1600 SIX-CORE 12 5,123 61,476 AMD
95 CORE I5-6500 CPU @ 3.20GHZ 4 15,051 60,204 Intel
96 CORE I5-4690 CPU @ 3.50GHZ 4 15,039 60,156 Intel
97 CORE I5-4670K CPU @ 3.40GHZ 4 14,897 59,588 Intel
98 CORE I5-7400 CPU @ 3.00GHZ 4 14,227 56,908 Intel
99 CORE I7-3720QM CPU @ 2.60GHZ 8 7,001 56,008 Intel
100 CORE I5-9300H CPU @ 2.40GHZ 8 6,793 54,344 Intel
101 CORE I5-6500T CPU @ 2.50GHZ 4 13,144 52,576 Intel
102 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,538 52,304 Intel
103 CORE I5-4590 CPU @ 3.30GHZ 4 12,912 51,648 Intel
104 11TH GEN CORE I5-1145G7 @ 2.60GHZ 8 6,321 50,568 Intel
105 CORE I5-8600T CPU @ 2.30GHZ 6 8,126 48,756 Intel
106 CORE I5-2500K CPU @ 3.30GHZ 4 12,063 48,252 Intel
107 CORE I5-8250U CPU @ 1.60GHZ 8 5,911 47,288 Intel
108 CORE I7-4770HQ CPU @ 2.20GHZ 8 5,874 46,992 Intel
109 CORE I5-4570 CPU @ 3.20GHZ 4 10,568 42,272 Intel
110 XEON CPU E3-1240 V2 @ 3.40GHZ 8 5,125 41,000 Intel
111 RYZEN 3 3200G 4 10,242 40,968 AMD
112 APPLE M1 8 5,058 40,464 Apple
113 CORE I7 CPU 975 @ 3.33GHZ 8 4,988 39,904 Intel
114 CORE I5-3570K CPU @ 3.40GHZ 4 9,913 39,652 Intel
115 PENTIUM(R) CPU G4560 @ 3.50GHZ 4 9,714 38,856 Intel
116 CORE I5-6600 CPU @ 3.30GHZ 4 9,632 38,528 Intel
117 XEON CPU E3-1220 V2 @ 3.10GHZ 4 9,622 38,488 Intel
118 CORE I5-8350U CPU @ 1.70GHZ 8 4,646 37,168 Intel
119 CORE I5-3570 CPU @ 3.40GHZ 4 9,015 36,060 Intel
120 CORE I5-8265U CPU @ 1.60GHZ 8 4,041 32,328 Intel
121 CORE I3-4170 CPU @ 3.70GHZ 4 7,787 31,148 Intel
122 RYZEN 5 PRO 2400G 8 3,869 30,952 AMD
123 APPLE M1 PRO 10 3,049 30,490 Apple
124 XEON CPU E31245 @ 3.30GHZ 8 3,414 27,312 Intel
125 XEON CPU E3-1245 V2 @ 3.40GHZ 8 3,401 27,208 Intel
126 CORE I7-3770K CPU @ 3.50GHZ 8 3,294 26,352 Intel
127 XEON CPU E5-2620 0 @ 2.00GHZ 12 2,151 25,812 Intel
128 RYZEN 5 2400G 8 2,814 22,512 AMD
129 FX-8150 EIGHT-CORE 8 2,636 21,088 AMD
130 XEON CPU E5-2650L V4 @ 1.70GHZ 28 744 20,832 Intel
131 CORE I7-8550U CPU @ 1.80GHZ 8 2,480 19,840 Intel
132 XEON CPU E5-2690 V2 @ 3.00GHZ 20 959 19,180 Intel
133 RYZEN 7 3700U 8 2,369 18,952 AMD
134 CORE I5-3470 CPU @ 3.20GHZ 4 4,721 18,884 Intel
135 CORE I5-5200U CPU @ 2.20GHZ 4 4,574 18,296 Intel
136 CORE I7-3667U CPU @ 2.00GHZ 4 3,884 15,536 Intel
137 CORE I5-4300U CPU @ 1.90GHZ 4 3,857 15,428 Intel
138 CORE I3-2120 CPU @ 3.30GHZ 4 3,148 12,592 Intel
139 CORE I3-6006U CPU @ 2.00GHZ 4 2,975 11,900 Intel
140 CORE I3-3225 CPU @ 3.30GHZ 4 2,917 11,668 Intel
141 CORE I3-3240 CPU @ 3.40GHZ 4 2,803 11,212 Intel
142 CORE I3-3220 CPU @ 3.30GHZ 4 2,739 10,956 Intel
143 CORE I5 CPU 750 @ 2.67GHZ 4 2,410 9,640 Intel
144 CORE I3-3110M CPU @ 2.40GHZ 4 1,691 6,764 Intel
145 CORE I3-1000NG4 CPU @ 1.10GHZ 4 1,369 5,476 Intel
146 CORE I5-7200U CPU @ 2.50GHZ 4 1,091 4,364 Intel
147 A12-9800 RADEON R7, 12 COMPUTE CORES 4C+8G 4 871 3,484 AMD
148 CELERON(R) J4125 CPU @ 2.00GHZ 4 694 2,776 Intel
149 PRO A10-9700 R7, 10 COMPUTE CORES 4C+6G 4 497 1,988 AMD
150 FX-4300 QUAD-CORE 4 364 1,456 AMD
151 A8-6410 APU 4 117 468 AMD