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PROJECT #18435 RESEARCH FOR BENCHMARK
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

These projects are simulations of so-called "host-guest" interactions, designed to test our ability to accurately predict the free energy of ligand binding.

The "host" in this particular system is a barrel-shaped pillarene with acidic functional groups, while the "guests" are cationic small molecules that like to bind inside the barrel.

Benchmarks like these are essential to continue advancing computational drug discovery efforts..

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 8,500

Core: 0xa8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Tuesday, 07 February 2023 06:14:50

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average
1 Iris(R) Iris Xe Graphics
TGL GT2 [Iris(R) Iris Xe Graphics]		 Intel TGL GT2 3,817 3,162 1.21 20 hrs 53 mins
2 Radeon HD 5600 Series
Redwood [Radeon HD 5600 Series]		 AMD Redwood 1,735 2,491 0.70 34 hrs 27 mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Tuesday, 07 February 2023 06:14:50

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 7900X 12-CORE 24 40,266 966,384 AMD
2 12TH GEN CORE I9-12900K 24 36,057 865,368 Intel
3 RYZEN 9 5950X 16-CORE 32 23,188 742,016 AMD
4 RYZEN 9 5900X 12-CORE 24 25,768 618,432 AMD
5 RYZEN 7 5800X3D 8-CORE 16 32,860 525,760 AMD
6 RYZEN 7 5800X 8-CORE 16 32,047 512,752 AMD
7 12TH GEN CORE I7-12700K 20 22,138 442,760 Intel
8 RYZEN 9 3900 12-CORE 24 17,333 415,992 AMD
9 RYZEN 7 5700G 16 25,999 415,984 AMD
10 12TH GEN CORE I5-12600K 16 24,722 395,552 Intel
11 11TH GEN CORE I9-11900K @ 3.50GHZ 16 23,273 372,368 Intel
12 RYZEN 9 3900X 12-CORE 24 15,501 372,024 AMD
13 11TH GEN CORE I7-11700K @ 3.60GHZ 16 21,599 345,584 Intel
14 RYZEN 7 3800X 8-CORE 16 15,515 248,240 AMD
15 RYZEN 7 3700X 8-CORE 16 15,413 246,608 AMD
16 CORE I9-10900X CPU @ 3.70GHZ 20 12,270 245,400 Intel
17 RYZEN 7 5700X 8-CORE 16 14,906 238,496 AMD
18 RYZEN 9 5900HS 16 12,471 199,536 AMD
19 RYZEN 5 PRO 5650G 12 16,083 192,996 AMD
20 CORE I7-9700K CPU @ 3.60GHZ 8 21,763 174,104 Intel
21 CORE I7-8700 CPU @ 3.20GHZ 12 14,079 168,948 Intel
22 RYZEN 5 5600H 12 13,593 163,116 AMD
23 CORE I5-8600K CPU @ 3.60GHZ 6 26,753 160,518 Intel
24 12TH GEN CORE I3-12100F 8 19,637 157,096 Intel
25 RYZEN 5 3500 6-CORE 6 25,298 151,788 AMD
26 RYZEN 7 4800H 16 9,215 147,440 AMD
27 RYZEN 5 3600 6-CORE 12 12,260 147,120 AMD
28 CORE I7-7700K CPU @ 4.20GHZ 8 16,206 129,648 Intel
29 CORE I7-8705G CPU @ 3.10GHZ 8 14,972 119,776 Intel
30 CORE I5-9600K CPU @ 3.70GHZ 6 19,747 118,482 Intel
31 RYZEN 3 3300X 4-CORE 8 13,560 108,480 AMD
32 RYZEN 7 2700X EIGHT-CORE 16 6,332 101,312 AMD
33 CORE I7-6700 CPU @ 3.40GHZ 8 12,114 96,912 Intel
34 CORE I7-4790K CPU @ 4.00GHZ 8 11,208 89,664 Intel
35 CORE I7-7700 CPU @ 3.60GHZ 8 11,143 89,144 Intel
36 APPLE M1 MAX 10 8,322 83,220 Apple
37 RYZEN 5 5500U 12 6,915 82,980 AMD
38 EPYC-ROME 8 9,684 77,472 AMD
39 CORE I7-9700 CPU @ 3.00GHZ 8 9,680 77,440 Intel
40 XEON CPU E3-1270 V5 @ 3.60GHZ 8 9,283 74,264 Intel
41 CORE I7-4790 CPU @ 3.60GHZ 8 9,008 72,064 Intel
42 CORE I7-4770K CPU @ 3.50GHZ 8 8,904 71,232 Intel
43 CORE I7-6700K CPU @ 4.00GHZ 8 8,441 67,528 Intel
44 XEON CPU E5-1630 V3 @ 3.70GHZ 8 8,388 67,104 Intel
45 XEON CPU X5570 @ 2.93GHZ 16 4,167 66,672 Intel
46 CORE I3-8300 CPU @ 3.70GHZ 4 14,962 59,848 Intel
47 RYZEN 5 1600 SIX-CORE 12 4,984 59,808 AMD
48 RYZEN 5 2600X SIX-CORE 12 4,929 59,148 AMD
49 CORE I5-6600K CPU @ 3.50GHZ 4 13,495 53,980 Intel
50 CORE I5-4690 CPU @ 3.50GHZ 4 13,462 53,848 Intel
51 CORE I5-7400 CPU @ 3.00GHZ 4 13,173 52,692 Intel
52 CORE I7-4980HQ CPU @ 2.80GHZ 8 6,490 51,920 Intel
53 CORE I7-4790T CPU @ 2.70GHZ 8 6,484 51,872 Intel
54 CORE I5-4590 CPU @ 3.30GHZ 4 12,498 49,992 Intel
55 CORE I7-6700HQ CPU @ 2.60GHZ 8 6,148 49,184 Intel
56 CORE I5-6500T CPU @ 2.50GHZ 4 12,248 48,992 Intel
57 CORE I5-8300H CPU @ 2.30GHZ 8 5,998 47,984 Intel
58 CORE I5-4670 CPU @ 3.40GHZ 4 11,944 47,776 Intel
59 CORE I5-6400 CPU @ 2.70GHZ 4 11,659 46,636 Intel
60 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 5,809 46,472 Intel
61 CORE I5-4690K CPU @ 3.50GHZ 4 11,581 46,324 Intel
62 RYZEN 3 3200G 4 10,989 43,956 AMD
63 CORE I7-4770HQ CPU @ 2.20GHZ 8 5,494 43,952 Intel
64 CORE I7-9750H CPU @ 2.60GHZ 12 3,568 42,816 Intel
65 CORE I5-6600 CPU @ 3.30GHZ 4 10,586 42,344 Intel
66 CORE I5-4570 CPU @ 3.20GHZ 4 10,448 41,792 Intel
67 XEON CPU E3-1240 V2 @ 3.40GHZ 8 4,943 39,544 Intel
68 RYZEN 5 5600X 6-CORE 12 3,228 38,736 AMD
69 CORE I7-7700HQ CPU @ 2.80GHZ 8 4,746 37,968 Intel
70 CORE I3-6100 CPU @ 3.70GHZ 4 9,044 36,176 Intel
71 CORE I5-6500 CPU @ 3.20GHZ 4 8,827 35,308 Intel
72 CORE I5-2500K CPU @ 3.30GHZ 4 8,758 35,032 Intel
73 CORE I7-3720QM CPU @ 2.60GHZ 8 4,352 34,816 Intel
74 CORE I5-8265U CPU @ 1.60GHZ 8 4,307 34,456 Intel
75 XEON CPU E3-1245 V2 @ 3.40GHZ 8 3,796 30,368 Intel
76 RYZEN 5 PRO 2400G 8 3,785 30,280 AMD
77 APPLE M1 8 3,742 29,936 Apple
78 CORE I5-3570 CPU @ 3.40GHZ 4 7,317 29,268 Intel
79 CORE I5-7600K CPU @ 3.80GHZ 4 7,144 28,576 Intel
80 XEON CPU E31245 @ 3.30GHZ 8 3,425 27,400 Intel
81 CORE I7-6500U CPU @ 2.50GHZ 4 6,536 26,144 Intel
82 CORE I5-3570K CPU @ 3.40GHZ 4 6,316 25,264 Intel
83 CORE I5-2520M CPU @ 2.50GHZ 4 5,962 23,848 Intel
84 CORE I3-9100 CPU @ 3.60GHZ 4 5,617 22,468 Intel
85 CORE I5-3550 CPU @ 3.30GHZ 4 5,470 21,880 Intel
86 11TH GEN CORE I3-1125G4 @ 2.00GHZ 8 2,432 19,456 Intel
87 PHENOM II X4 965 4 4,793 19,172 AMD
88 CORE I5-3470 CPU @ 3.20GHZ 4 4,736 18,944 Intel
89 CORE I5-10210U CPU @ 1.60GHZ 7 2,534 17,738 Intel
90 CORE I7-2760QM CPU @ 2.40GHZ 8 2,204 17,632 Intel
91 CORE I7-7600U CPU @ 2.80GHZ 4 4,323 17,292 Intel
92 CORE I7-7500U CPU @ 2.70GHZ 4 4,169 16,676 Intel
93 CORE I3-2120 CPU @ 3.30GHZ 4 3,851 15,404 Intel
94 CORE I5-4300U CPU @ 1.90GHZ 4 3,443 13,772 Intel
95 CORE I3-3240 CPU @ 3.40GHZ 4 3,003 12,012 Intel
96 CORE I5-7200U CPU @ 2.50GHZ 4 2,710 10,840 Intel
97 CORE I5-3210M CPU @ 2.50GHZ 4 2,649 10,596 Intel
98 CORE I3-3225 CPU @ 3.30GHZ 4 2,616 10,464 Intel
99 CORE I3-6006U CPU @ 2.00GHZ 4 2,313 9,252 Intel
100 CORE I3-3220 CPU @ 3.30GHZ 4 2,237 8,948 Intel
101 CORE I5 CPU 650 @ 3.20GHZ 4 2,214 8,856 Intel
102 PRO A10-9700 R7, 10 COMPUTE CORES 4C+6G 4 1,694 6,776 AMD
103 CORE I7 CPU 975 @ 3.33GHZ 8 840 6,720 Intel
104 CORE I3-1000NG4 CPU @ 1.10GHZ 4 1,591 6,364 Intel
105 PENTIUM(R) CPU 5405U @ 2.30GHZ 4 1,239 4,956 Intel
106 FX-8350 EIGHT-CORE 8 511 4,088 AMD
107 PENTIUM(R) CPU 2127U @ 1.90GHZ 2 1,985 3,970 Intel
108 CORE I5-3570S CPU @ 3.10GHZ 4 775 3,100 Intel
109 CORE2 DUO CPU E8400 @ 3.00GHZ 2 1,423 2,846 Intel
110 XEON CPU @ 2.20GHZ 1 2,839 2,839 Intel
111 CORE I7-3520M CPU @ 2.90GHZ 4 471 1,884 Intel
112 A8-6410 APU 4 221 884 AMD
113 ATHLON(TM) 64 X2 DUAL CORE 4200+ 2 426 852 AMD
114 FX-4300 QUAD-CORE 4 184 736 AMD