Research section Research projects and references

Research: CANCER Folding Project #17629

Project #17629 overview

Project Summary AI Beta

The project relates to using computer simulations to study how small changes in proteins can affect their function. Scientists are focusing on a complex protein called RIPK2, which forms pairs with other proteins. They're testing different mutations and seeing how they impact the protein's ability to interact with its partner.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Sukrit Singh
Institution
Memorial Sloan-Kettering Cancer-Center

Work unit

Atoms
329,840
Core
0x22
Status
Public
Source material

Official Project Description

The previous FEC work unit test was completed successfully so now we're running larger "full size" WUs that are more scientifically useful for studying protein mutations with Free Energy Calculations.

As before, the approach and technology are similar to the Moonshot, but these set of projects instead are studying protein mutations and are much larger (since proteins are also much larger) In this case we are trying out multiple mutations and their impact upon a protein-protein of a dimerization complex (RIPK2), the most complex case.

Performance data

Hardware Performance for Project 17629

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 21:57:31

GPU PPD Averages

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average
1 GeForce RTX 3090
GA102 [GeForce RTX 3090]
Nvidia GA102 7,561,283 1,912,275 3.95 6 hrs 4 mins
2 GeForce RTX 3080 Ti
GA102 [GeForce RTX 3080 Ti]
Nvidia GA102 6,746,465 1,875,522 3.60 6 hrs 40 mins
3 Radeon RX 6800/6800 XT / 6900 XT
Navi 21 [Radeon RX 6800/6800 XT / 6900 XT]
AMD Navi 21 4,812,855 1,635,083 2.94 8 hrs 9 mins
4 GeForce GTX 1070
GP104 [GeForce GTX 1070] 6463
Nvidia GP104 986,079 994,736 0.99 24 hrs 13 mins
5 GeForce RTX 2060
TU104 [GeForce RTX 2060]
Nvidia TU104 799,235 1,096,640 0.73 32 hrs 56 mins