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Research: CANCER Folding Project #17622

Project #17622 overview

Project Summary AI Beta

Scientists are using powerful computer simulations to study how changes in proteins can affect their function. They're focusing on a complex protein called RIPK2, which is involved in immune responses. By making tiny changes to the protein and observing the results, they hope to gain a better understanding of diseases and develop new treatments.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Sukrit Singh
Institution
Memorial Sloan-Kettering Cancer-Center

Work unit

Atoms
329,840
Core
0x22
Status
Public
Source material

Official Project Description

The previous FEC work unit test was completed successfully so now we're running larger "full size" WUs that are more scientifically useful for studying protein mutations with Free Energy Calculations.

As before, the approach and technology are similar to the Moonshot, but these set of projects instead are studying protein mutations and are much larger (since proteins are also much larger) In this case we are trying out multiple mutations and their impact upon a protein-protein of a dimerization complex (RIPK2), the most complex case.

Performance data

Hardware Performance for Project 17622

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Friday, 14 August 2026 15:32:03

GPU PPD Averages

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average
1 GeForce RTX 3090
GA102 [GeForce RTX 3090]		 Nvidia GA102 7,408,345 1,901,972 3.90 6 hrs 10 mins
2 GeForce RTX 3070 Lite Hash Rate
GA104 [GeForce RTX 3070 Lite Hash Rate]		 Nvidia GA104 3,517,530 1,484,236 2.37 10 hrs 8 mins
3 GeForce RTX 2080 Ti Rev. A
TU102 [GeForce RTX 2080 Ti Rev. A] M 13448		 Nvidia TU102 3,017,087 1,570,741 1.92 12 hrs 30 mins
4 GeForce GTX 1080 Ti
GP102 [GeForce GTX 1080 Ti] 11380		 Nvidia GP102 1,755,507 1,299,604 1.35 17 hrs 46 mins
5 GeForce GTX 980
GM204 [GeForce GTX 980] 4612		 Nvidia GM204 832,076 919,692 0.90 26 hrs 32 mins