PROJECT #16955 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This project simulations the dynamics of the human enzyme lactate dehydrogenase (LDH), the key metabolic enzyme that converts lactate to pyruvate and back.   We are simulating apo and holo-state dynamics to study how this enzyme binds inhibitors, which should lead to a better understanding of allostery and inform new computational drug discovery efforts.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 151,566

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 16 January 2022 11:42:03

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average
1 Iris(R) Iris Xe Graphics
TGL GT2 [Iris(R) Iris Xe Graphics]
TGL GT2 4,720 6,444 0.73 33 hrs 46 mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 16 January 2022 11:42:03

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 XEON E-2124G CPU @ 3.40GHZ 4 1,105,019 4,420,076 Intel
2 RYZEN THREADRIPPER 3970X 32-CORE 64 17,099 1,094,336 AMD
3 RYZEN 9 3950X 16-CORE 32 20,214 646,848 AMD
4 RYZEN 9 5950X 16-CORE 32 18,899 604,768 AMD
5 RYZEN 7 5800X 8-CORE 16 33,103 529,648 AMD
6 RYZEN 7 5700G 16 29,632 474,112 AMD
7 CORE I9-7920X CPU @ 2.90GHZ 24 19,664 471,936 Intel
8 RYZEN 9 5900X 12-CORE 24 17,120 410,880 AMD
9 11TH GEN CORE I9-11900K @ 3.50GHZ 16 23,864 381,824 Intel
10 XEON CPU E5-2670 0 @ 2.60GHZ 32 11,879 380,128 Intel
11 RYZEN THREADRIPPER 2970WX 24-CORE 48 7,702 369,696 AMD
12 RYZEN 9 3900X 12-CORE 24 15,390 369,360 AMD
13 RYZEN 9 3900 12-CORE 24 15,224 365,376 AMD
14 RYZEN 9 3900XT 12-CORE 24 13,884 333,216 AMD
15 RYZEN THREADRIPPER 3960X 24-CORE 48 6,621 317,808 AMD
16 CORE I9-9900K CPU @ 3.60GHZ 16 19,605 313,680 Intel
17 CORE I9-10850K CPU @ 3.60GHZ 20 14,770 295,400 Intel
18 RYZEN 7 3800X 8-CORE 16 18,280 292,480 AMD
19 XEON CPU E5-2690 V4 @ 2.60GHZ 28 10,029 280,812 Intel
20 RYZEN THREADRIPPER 2950X 16-CORE 32 8,302 265,664 AMD
21 CORE I9-10900X CPU @ 3.70GHZ 20 13,166 263,320 Intel
22 RYZEN 7 3700X 8-CORE 16 16,316 261,056 AMD
23 CORE I7-9700K CPU @ 3.60GHZ 8 30,840 246,720 Intel
24 XEON CPU E5-2667 V2 @ 3.30GHZ 32 7,647 244,704 Intel
25 11TH GEN CORE I7-11700K @ 3.60GHZ 16 15,138 242,208 Intel
26 XEON CPU E5-2680 V3 @ 2.50GHZ 24 8,994 215,856 Intel
27 RYZEN 5 5600X 6-CORE 12 17,211 206,532 AMD
28 11TH GEN CORE I7-11850H @ 2.50GHZ 16 12,853 205,648 Intel
29 CORE I7-5960X CPU @ 3.00GHZ 16 12,694 203,104 Intel
30 CORE I7-10700K CPU @ 3.80GHZ 16 12,547 200,752 Intel
31 CORE I7-8700 CPU @ 3.20GHZ 12 16,414 196,968 Intel
32 CORE I9-9900 CPU @ 3.10GHZ 16 11,979 191,664 Intel
33 11TH GEN CORE I5-11600K @ 3.90GHZ 12 15,655 187,860 Intel
34 XEON CPU E5-2660 V3 @ 2.60GHZ 20 9,181 183,620 Intel
35 CORE I7-10700 CPU @ 2.90GHZ 16 11,463 183,408 Intel
36 XEON W-2175 CPU @ 2.50GHZ 28 6,457 180,796 Intel
37 CORE I7-9700 CPU @ 3.00GHZ 8 21,628 173,024 Intel
38 RYZEN 5 2600X SIX-CORE 12 13,656 163,872 AMD
39 RYZEN 7 PRO 4750G 16 10,023 160,368 AMD
40 RYZEN THREADRIPPER 1920X 12-CORE 24 6,569 157,656 AMD
41 CORE I5-10400 CPU @ 2.90GHZ 12 12,454 149,448 Intel
42 RYZEN 7 4800H 16 9,172 146,752 AMD
43 RYZEN 5 3600 6-CORE 12 11,749 140,988 AMD
44 CORE I7-9700T CPU @ 2.00GHZ 8 17,129 137,032 Intel
45 11TH GEN CORE I9-11900F @ 2.50GHZ 16 8,235 131,760 Intel
46 RYZEN 7 2700X EIGHT-CORE 16 7,577 121,232 AMD
47 CORE I3-10105F CPU @ 3.70GHZ 8 14,797 118,376 Intel
48 CORE I5-10400F CPU @ 2.90GHZ 12 9,755 117,060 Intel
49 CORE I9-9880H CPU @ 2.30GHZ 16 6,965 111,440 Intel
50 CORE I7-10870H CPU @ 2.20GHZ 16 6,941 111,056 Intel
51 CORE I7-8700B CPU @ 3.20GHZ 12 8,447 101,364 Intel
52 CORE I7-10700T CPU @ 2.00GHZ 16 6,116 97,856 Intel
53 RYZEN 3 3100 4-CORE 8 11,981 95,848 AMD
54 CORE I3-6006U CPU @ 2.00GHZ 4 23,931 95,724 Intel
55 CORE I7-7700 CPU @ 3.60GHZ 8 11,887 95,096 Intel
56 CORE I5-4300U CPU @ 1.90GHZ 4 23,301 93,204 Intel
57 CORE I7-5820K CPU @ 3.30GHZ 12 7,758 93,096 Intel
58 11TH GEN CORE I5-11400 @ 2.60GHZ 12 7,607 91,284 Intel
59 CORE I7-6700 CPU @ 3.40GHZ 8 10,805 86,440 Intel
60 CORE I7-8705G CPU @ 3.10GHZ 8 10,680 85,440 Intel
61 CORE I7-4790K CPU @ 4.00GHZ 8 10,492 83,936 Intel
62 CORE I7-6700K CPU @ 4.00GHZ 8 10,255 82,040 Intel
63 CORE I7-10750H CPU @ 2.60GHZ 12 6,665 79,980 Intel
64 RYZEN 5 2600 SIX-CORE 12 6,517 78,204 AMD
65 RYZEN 5 1600 SIX-CORE 12 6,503 78,036 AMD
66 CORE I3-8100 CPU @ 3.60GHZ 4 18,934 75,736 Intel
67 CORE I5-8400 CPU @ 2.80GHZ 6 12,029 72,174 Intel
68 CORE I5-7600 CPU @ 3.50GHZ 4 17,702 70,808 Intel
69 CORE I7-1065G7 CPU @ 1.30GHZ 8 8,804 70,432 Intel
70 RYZEN 5 3600X 6-CORE 12 5,863 70,356 AMD
71 RYZEN 7 5700U 16 4,365 69,840 AMD
72 XEON W-10855M CPU @ 2.80GHZ 12 5,565 66,780 Intel
73 GENUINE CPU 0000 @ 2.70GHZ 8 8,312 66,496 Intel
74 CORE I7-8550U CPU @ 1.80GHZ 8 8,302 66,416 Intel
75 EPYC 7251 8-CORE 16 4,138 66,208 AMD
76 CORE I5-7400 CPU @ 3.00GHZ 4 15,495 61,980 Intel
77 CORE I5-5200U CPU @ 2.20GHZ 4 15,250 61,000 Intel
78 CORE I9-8950HK CPU @ 2.90GHZ 12 4,855 58,260 Intel
79 CORE I7-4980HQ CPU @ 2.80GHZ 8 7,180 57,440 Intel
80 CORE I7-10510U CPU @ 1.80GHZ 8 7,163 57,304 Intel
81 CORE I5-8300H CPU @ 2.30GHZ 8 7,065 56,520 Intel
82 CORE I7-10610U CPU @ 1.80GHZ 8 6,658 53,264 Intel
83 XEON CPU X5570 @ 2.93GHZ 16 3,286 52,576 Intel
84 CORE I5-6500T CPU @ 2.50GHZ 4 13,088 52,352 Intel
85 11TH GEN CORE I7-1165G7 @ 2.80GHZ 8 6,338 50,704 Intel
86 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 6,330 50,640 Intel
87 CORE I7-4790T CPU @ 2.70GHZ 8 6,307 50,456 Intel
88 CORE I3-8100T CPU @ 3.10GHZ 4 12,015 48,060 Intel
89 CORE I5-4670 CPU @ 3.40GHZ 4 11,905 47,620 Intel
90 CORE I5-4690K CPU @ 3.50GHZ 4 11,821 47,284 Intel
91 RYZEN 5 5500U 12 3,901 46,812 AMD
92 CELERON(R) CPU 847 @ 1.10GHZ 2 23,005 46,010 Intel
93 CORE I7-4770HQ CPU @ 2.20GHZ 8 5,594 44,752 Intel
94 CORE I5-4590 CPU @ 3.30GHZ 4 10,997 43,988 Intel
95 CORE I7-7700HQ CPU @ 2.80GHZ 8 5,469 43,752 Intel
96 CORE I5-6400 CPU @ 2.70GHZ 4 10,813 43,252 Intel
97 CORE I5-8259U CPU @ 2.30GHZ 8 5,351 42,808 Intel
98 CORE I5-6600K CPU @ 3.50GHZ 4 10,596 42,384 Intel
99 RYZEN 3 3200G 4 10,492 41,968 AMD
100 XEON CPU E5-1620 0 @ 3.60GHZ 8 5,221 41,768 Intel
101 CORE I3-10100 CPU @ 3.60GHZ 8 5,212 41,696 Intel
102 CORE I5-4570 CPU @ 3.20GHZ 4 10,317 41,268 Intel
103 CORE I7-3770 CPU @ 3.40GHZ 8 5,154 41,232 Intel
104 XEON CPU E3-1241 V3 @ 3.50GHZ 8 4,940 39,520 Intel
105 RYZEN 5 3400G 8 4,870 38,960 AMD
106 CORE I5-4570S CPU @ 2.90GHZ 4 9,620 38,480 Intel
107 CORE I5-8250U CPU @ 1.60GHZ 8 4,800 38,400 Intel
108 CORE I5-8265U CPU @ 1.60GHZ 8 4,794 38,352 Intel
109 XEON CPU X5670 @ 2.93GHZ 12 3,185 38,220 Intel
110 CORE I5-6300HQ CPU @ 2.30GHZ 4 9,436 37,744 Intel
111 CORE I7-4765T CPU @ 2.00GHZ 8 4,693 37,544 Intel
112 CORE I7-3840QM CPU @ 2.80GHZ 8 4,643 37,144 Intel
113 CORE I7-4770K CPU @ 3.50GHZ 8 4,577 36,616 Intel
114 CORE I3-6100 CPU @ 3.70GHZ 4 8,995 35,980 Intel
115 XEON CPU E3-1245 V2 @ 3.40GHZ 8 4,377 35,016 Intel
116 CORE I7-4850HQ CPU @ 2.30GHZ 8 4,312 34,496 Intel
117 CORE I5-3330 CPU @ 3.00GHZ 4 8,474 33,896 Intel
118 XEON CPU E5-2620 0 @ 2.00GHZ 12 2,802 33,624 Intel
119 CORE I5-6600 CPU @ 3.30GHZ 4 8,153 32,612 Intel
120 XEON CPU E5-2678 V3 @ 2.50GHZ 6 5,421 32,526 Intel
121 CORE I5-3570 CPU @ 3.40GHZ 4 7,622 30,488 Intel
122 CORE I7-6500U CPU @ 2.50GHZ 4 7,491 29,964 Intel
123 XEON CPU E5-2450 0 @ 2.10GHZ 10 2,957 29,570 Intel
124 CORE I5-2500K CPU @ 3.30GHZ 4 7,293 29,172 Intel
125 CORE I3-7100 CPU @ 3.90GHZ 4 7,234 28,936 Intel
126 XEON CPU E31245 @ 3.30GHZ 8 3,460 27,680 Intel
127 CORE I5-4278U CPU @ 2.60GHZ 4 6,889 27,556 Intel
128 CORE I7-2600 CPU @ 3.40GHZ 8 3,255 26,040 Intel
129 CORE I3-3240 CPU @ 3.40GHZ 4 6,317 25,268 Intel
130 CORE I7-3610QM CPU @ 2.30GHZ 8 3,034 24,272 Intel
131 XEON CPU W3550 @ 3.07GHZ 8 2,962 23,696 Intel
132 CORE I7-8565U CPU @ 1.80GHZ 8 2,630 21,040 Intel
133 CORE I7-7500U CPU @ 2.70GHZ 4 5,010 20,040 Intel
134 CORE I7 CPU 975 @ 3.33GHZ 8 2,488 19,904 Intel
135 CORE I7-7Y75 CPU @ 1.30GHZ 4 4,935 19,740 Intel
136 CORE I3-4130 CPU @ 3.40GHZ 4 4,896 19,584 Intel
137 CORE I5-3470 CPU @ 3.20GHZ 4 4,787 19,148 Intel
138 CORE I5-6300U CPU @ 2.40GHZ 4 4,319 17,276 Intel
139 CORE I5-7200U CPU @ 2.50GHZ 4 4,136 16,544 Intel
140 CORE M3-7Y30 CPU @ 1.00GHZ 4 3,726 14,904 Intel
141 CORE2 QUAD CPU Q9550 @ 2.83GHZ 4 2,976 11,904 Intel
142 PENTIUM(R) GOLD G5400 CPU @ 3.70GHZ 4 2,748 10,992 Intel
143 CORE I3-3225 CPU @ 3.30GHZ 4 2,589 10,356 Intel
144 CORE I3-3110M CPU @ 2.40GHZ 4 2,430 9,720 Intel
145 RYZEN 3 3200U 4 2,331 9,324 AMD
146 RYZEN 3 2200G 4 2,302 9,208 AMD
147 RYZEN 5 3500U 8 988 7,904 AMD
148 A10-6700 APU RADEON(TM) HD GRAPHICS 4 1,893 7,572 AMD
149 FX-8800P RADEON R7, 12 COMPUTE CORES 4C+8G 4 1,879 7,516 AMD
150 FX-4350 QUAD-CORE 4 1,213 4,852 AMD
151 CORE I5-9300H CPU @ 2.40GHZ 8 596 4,768 Intel
152 CORE2 DUO CPU E8400 @ 3.00GHZ 2 2,355 4,710 Intel
153 RYZEN 3 3250U 4 1,129 4,516 AMD
154 FX-4300 QUAD-CORE 4 974 3,896 AMD
155 A8-6410 APU 4 358 1,432 AMD
156 ATOM(TM) X5-Z8350 CPU @ 1.44GHZ 4 255 1,020 Intel
157 PENTIUM(R) CPU G2020T @ 2.50GHZ 2 369 738 Intel