PROJECT #16955 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This project simulations the dynamics of the human enzyme lactate dehydrogenase (LDH), the key metabolic enzyme that converts lactate to pyruvate and back.   We are simulating apo and holo-state dynamics to study how this enzyme binds inhibitors, which should lead to a better understanding of allostery and inform new computational drug discovery efforts.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 151,566

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Friday, 30 July 2021 03:40:23

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Friday, 30 July 2021 03:40:23

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 26,133 836,256 AMD
2 RYZEN 9 5950X 16-CORE 32 23,643 756,576 AMD
3 CORE I5-4300U CPU @ 1.90GHZ 4 148,148 592,592 Intel
4 RYZEN 9 5900X 12-CORE 24 18,927 454,248 AMD
5 CORE I9-9900K CPU @ 3.60GHZ 16 27,429 438,864 Intel
6 RYZEN 7 5800X 8-CORE 16 24,504 392,064 AMD
7 RYZEN THREADRIPPER 3960X 24-CORE 48 7,858 377,184 AMD
8 RYZEN THREADRIPPER 2970WX 24-CORE 48 7,840 376,320 AMD
9 RYZEN 9 3900XT 12-CORE 24 15,229 365,496 AMD
10 RYZEN THREADRIPPER 2950X 16-CORE 32 11,329 362,528 AMD
11 RYZEN 9 3900 12-CORE 24 14,933 358,392 AMD
12 XEON CPU E5-2690 V4 @ 2.60GHZ 28 11,091 310,548 Intel
13 CORE I9-10900X CPU @ 3.70GHZ 20 14,255 285,100 Intel
14 CORE I7-9700K CPU @ 3.60GHZ 8 34,107 272,856 Intel
15 RYZEN 7 3700X 8-CORE 16 16,332 261,312 AMD
16 XEON CPU E5-2667 V2 @ 3.30GHZ 32 7,647 244,704 Intel
17 11TH GEN CORE I7-11700K @ 3.60GHZ 16 14,537 232,592 Intel
18 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,366 224,784 Intel
19 RYZEN 5 5600X 6-CORE 12 17,488 209,856 AMD
20 CORE I7-10700K CPU @ 3.80GHZ 16 12,547 200,752 Intel
21 11TH GEN CORE I5-11600K @ 3.90GHZ 12 15,655 187,860 Intel
22 CORE I7-10700 CPU @ 2.90GHZ 16 11,500 184,000 Intel
23 CORE I7-8700 CPU @ 3.20GHZ 12 14,207 170,484 Intel
24 11TH GEN CORE I9-11900K @ 3.50GHZ 16 10,564 169,024 Intel
25 RYZEN 7 3800X 8-CORE 16 10,516 168,256 AMD
26 11TH GEN CORE I9-11900F @ 2.50GHZ 16 10,023 160,368 Intel
27 RYZEN 5 3600 6-CORE 12 13,213 158,556 AMD
28 RYZEN THREADRIPPER 1920X 12-CORE 24 6,019 144,456 AMD
29 CORE I5-10400 CPU @ 2.90GHZ 12 11,587 139,044 Intel
30 CORE I7-9700T CPU @ 2.00GHZ 8 17,129 137,032 Intel
31 RYZEN 7 2700X EIGHT-CORE 16 8,256 132,096 AMD
32 CORE I7-10870H CPU @ 2.20GHZ 16 7,753 124,048 Intel
33 CORE I5-10400F CPU @ 2.90GHZ 12 8,996 107,952 Intel
34 RYZEN 7 4800H 16 6,632 106,112 AMD
35 CORE I7-8700B CPU @ 3.20GHZ 12 8,447 101,364 Intel
36 RYZEN 3 3100 4-CORE 8 11,981 95,848 AMD
37 11TH GEN CORE I5-11400 @ 2.60GHZ 12 7,497 89,964 Intel
38 CORE I5-8400 CPU @ 2.80GHZ 6 14,045 84,270 Intel
39 CORE I7-6700K CPU @ 4.00GHZ 8 10,533 84,264 Intel
40 CORE I7-6700 CPU @ 3.40GHZ 8 10,214 81,712 Intel
41 RYZEN 5 2600 SIX-CORE 12 6,773 81,276 AMD
42 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 8,920 71,360 Intel
43 CORE I7-4790K CPU @ 4.00GHZ 8 8,639 69,112 Intel
44 CORE I5-7600 CPU @ 3.50GHZ 4 16,814 67,256 Intel
45 CORE I7-8550U CPU @ 1.80GHZ 8 8,302 66,416 Intel
46 XEON W-10855M CPU @ 2.80GHZ 12 5,393 64,716 Intel
47 CORE I5-8300H CPU @ 2.30GHZ 8 7,561 60,488 Intel
48 CORE I5-7400 CPU @ 3.00GHZ 4 14,375 57,500 Intel
49 CORE I7-7700 CPU @ 3.60GHZ 8 7,094 56,752 Intel
50 CORE I5-4690K CPU @ 3.50GHZ 4 13,532 54,128 Intel
51 CORE I7-4790T CPU @ 2.70GHZ 8 6,584 52,672 Intel
52 CORE I3-8100T CPU @ 3.10GHZ 4 12,015 48,060 Intel
53 CORE I5-4590 CPU @ 3.30GHZ 4 11,201 44,804 Intel
54 XEON CPU E3-1241 V3 @ 3.50GHZ 8 4,940 39,520 Intel
55 CORE I5-4570S CPU @ 2.90GHZ 4 9,620 38,480 Intel
56 CORE I5-8250U CPU @ 1.60GHZ 8 4,800 38,400 Intel
57 XEON CPU X5670 @ 2.93GHZ 12 3,185 38,220 Intel
58 CORE I7-3840QM CPU @ 2.80GHZ 8 4,643 37,144 Intel
59 CORE I3-8100 CPU @ 3.60GHZ 4 9,087 36,348 Intel
60 CORE I5-6600K CPU @ 3.50GHZ 4 9,077 36,308 Intel
61 CORE I7-4770K CPU @ 3.50GHZ 8 4,415 35,320 Intel
62 CORE I7-4850HQ CPU @ 2.30GHZ 8 4,312 34,496 Intel
63 CORE I5-3330 CPU @ 3.00GHZ 4 8,474 33,896 Intel
64 XEON CPU E5-2678 V3 @ 2.50GHZ 6 5,421 32,526 Intel
65 CORE I5-4570 CPU @ 3.20GHZ 4 7,997 31,988 Intel
66 CORE I5-3570 CPU @ 3.40GHZ 4 7,655 30,620 Intel
67 CORE I3-7100 CPU @ 3.90GHZ 4 7,234 28,936 Intel
68 CORE I7-3610QM CPU @ 2.30GHZ 8 3,034 24,272 Intel
69 XEON CPU W3550 @ 3.07GHZ 8 2,962 23,696 Intel
70 CORE I7-8565U CPU @ 1.80GHZ 8 2,630 21,040 Intel
71 CORE I3-4130 CPU @ 3.40GHZ 4 4,896 19,584 Intel
72 CORE I7-2600 CPU @ 3.40GHZ 8 2,335 18,680 Intel
73 CORE I5-6300U CPU @ 2.40GHZ 4 4,565 18,260 Intel
74 CORE M3-7Y30 CPU @ 1.00GHZ 4 3,751 15,004 Intel
75 CORE I3-6006U CPU @ 2.00GHZ 4 3,212 12,848 Intel
76 CORE2 QUAD CPU Q9550 @ 2.83GHZ 4 2,976 11,904 Intel
77 PENTIUM(R) GOLD G5400 CPU @ 3.70GHZ 4 2,748 10,992 Intel
78 CORE I3-3110M CPU @ 2.40GHZ 4 2,430 9,720 Intel
79 RYZEN 3 3200U 4 2,331 9,324 AMD
80 CORE I5-7200U CPU @ 2.50GHZ 4 2,174 8,696 Intel
81 A10-6700 APU RADEON(TM) HD GRAPHICS 4 1,893 7,572 AMD
82 FX-8800P RADEON R7, 12 COMPUTE CORES 4C+8G 4 1,879 7,516 AMD
83 CORE2 DUO CPU E8400 @ 3.00GHZ 2 3,399 6,798 Intel
84 FX-4350 QUAD-CORE 4 1,213 4,852 AMD
85 A8-6410 APU 4 387 1,548 AMD