PROJECT #16955 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This project simulations the dynamics of the human enzyme lactate dehydrogenase (LDH), the key metabolic enzyme that converts lactate to pyruvate and back.   We are simulating apo and holo-state dynamics to study how this enzyme binds inhibitors, which should lead to a better understanding of allostery and inform new computational drug discovery efforts.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 151,566

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Sunday, 17 October 2021 11:36:00

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Sunday, 17 October 2021 11:36:00

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 3950X 16-CORE 32 26,434 845,888 AMD
2 RYZEN 9 5950X 16-CORE 32 22,375 716,000 AMD
3 CORE I5-4300U CPU @ 1.90GHZ 4 148,148 592,592 Intel
4 RYZEN 7 5800X 8-CORE 16 32,817 525,072 AMD
5 CORE I3-6006U CPU @ 2.00GHZ 4 117,324 469,296 Intel
6 RYZEN 9 5900X 12-CORE 24 18,256 438,144 AMD
7 RYZEN THREADRIPPER 2970WX 24-CORE 48 7,840 376,320 AMD
8 RYZEN 9 3900XT 12-CORE 24 15,229 365,496 AMD
9 RYZEN THREADRIPPER 2950X 16-CORE 32 11,329 362,528 AMD
10 RYZEN 9 3900 12-CORE 24 14,933 358,392 AMD
11 RYZEN THREADRIPPER 3960X 24-CORE 48 6,621 317,808 AMD
12 CORE I9-9900K CPU @ 3.60GHZ 16 19,605 313,680 Intel
13 CORE I9-10850K CPU @ 3.60GHZ 20 14,770 295,400 Intel
14 RYZEN 7 3800X 8-CORE 16 17,798 284,768 AMD
15 XEON CPU E5-2690 V4 @ 2.60GHZ 28 9,992 279,776 Intel
16 CORE I9-10900X CPU @ 3.70GHZ 20 13,816 276,320 Intel
17 RYZEN 7 3700X 8-CORE 16 16,738 267,808 AMD
18 CORE I7-9700K CPU @ 3.60GHZ 8 30,840 246,720 Intel
19 XEON CPU E5-2667 V2 @ 3.30GHZ 32 7,647 244,704 Intel
20 11TH GEN CORE I7-11700K @ 3.60GHZ 16 14,565 233,040 Intel
21 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,414 225,936 Intel
22 RYZEN 5 5600X 6-CORE 12 17,372 208,464 AMD
23 CORE I7-8700 CPU @ 3.20GHZ 12 17,315 207,780 Intel
24 CORE I7-10700K CPU @ 3.80GHZ 16 12,547 200,752 Intel
25 CORE I9-9900 CPU @ 3.10GHZ 16 11,979 191,664 Intel
26 11TH GEN CORE I5-11600K @ 3.90GHZ 12 15,655 187,860 Intel
27 CORE I7-10700 CPU @ 2.90GHZ 16 11,500 184,000 Intel
28 XEON W-2175 CPU @ 2.50GHZ 28 6,457 180,796 Intel
29 CORE I7-9700 CPU @ 3.00GHZ 8 21,628 173,024 Intel
30 11TH GEN CORE I9-11900K @ 3.50GHZ 16 10,564 169,024 Intel
31 RYZEN 5 2600X SIX-CORE 12 13,561 162,732 AMD
32 11TH GEN CORE I9-11900F @ 2.50GHZ 16 10,023 160,368 Intel
33 RYZEN THREADRIPPER 1920X 12-CORE 24 6,569 157,656 AMD
34 RYZEN 5 3600 6-CORE 12 13,075 156,900 AMD
35 RYZEN 7 4800H 16 9,172 146,752 AMD
36 CORE I5-10400 CPU @ 2.90GHZ 12 12,028 144,336 Intel
37 CORE I7-9700T CPU @ 2.00GHZ 8 17,129 137,032 Intel
38 CORE I3-10105F CPU @ 3.70GHZ 8 14,797 118,376 Intel
39 CORE I5-10400F CPU @ 2.90GHZ 12 9,755 117,060 Intel
40 CORE I7-10870H CPU @ 2.20GHZ 16 6,941 111,056 Intel
41 RYZEN 7 2700X EIGHT-CORE 16 6,701 107,216 AMD
42 CORE I7-8700B CPU @ 3.20GHZ 12 8,447 101,364 Intel
43 RYZEN 3 3100 4-CORE 8 11,981 95,848 AMD
44 CORE I7-5820K CPU @ 3.30GHZ 12 7,758 93,096 Intel
45 CORE I7-7700 CPU @ 3.60GHZ 8 10,687 85,496 Intel
46 CORE I7-8705G CPU @ 3.10GHZ 8 10,672 85,376 Intel
47 CORE I7-6700K CPU @ 4.00GHZ 8 10,255 82,040 Intel
48 CORE I7-6700 CPU @ 3.40GHZ 8 10,214 81,712 Intel
49 CORE I5-8400 CPU @ 2.80GHZ 6 13,348 80,088 Intel
50 RYZEN 5 2600 SIX-CORE 12 6,475 77,700 AMD
51 11TH GEN CORE I5-11400 @ 2.60GHZ 12 6,315 75,780 Intel
52 CORE I7-10750H CPU @ 2.60GHZ 12 6,002 72,024 Intel
53 CORE I7-1065G7 CPU @ 1.30GHZ 8 8,804 70,432 Intel
54 CORE I7-4790K CPU @ 4.00GHZ 8 8,639 69,112 Intel
55 XEON W-10855M CPU @ 2.80GHZ 12 5,565 66,780 Intel
56 CORE I7-8550U CPU @ 1.80GHZ 8 8,302 66,416 Intel
57 EPYC 7251 8-CORE 16 4,138 66,208 AMD
58 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 7,782 62,256 Intel
59 CORE I5-8300H CPU @ 2.30GHZ 8 7,561 60,488 Intel
60 CORE I5-7400 CPU @ 3.00GHZ 4 14,915 59,660 Intel
61 CORE I7-10510U CPU @ 1.80GHZ 8 7,163 57,304 Intel
62 CORE I5-7600 CPU @ 3.50GHZ 4 13,970 55,880 Intel
63 CORE I9-8950HK CPU @ 2.90GHZ 12 4,455 53,460 Intel
64 CORE I5-6400 CPU @ 2.70GHZ 4 13,347 53,388 Intel
65 CORE I7-4790T CPU @ 2.70GHZ 8 6,066 48,528 Intel
66 CORE I3-8100T CPU @ 3.10GHZ 4 12,015 48,060 Intel
67 CORE I5-4690K CPU @ 3.50GHZ 4 11,821 47,284 Intel
68 CORE I3-10100 CPU @ 3.60GHZ 8 5,679 45,432 Intel
69 CORE I5-4590 CPU @ 3.30GHZ 4 11,199 44,796 Intel
70 CORE I7-7700HQ CPU @ 2.80GHZ 8 5,469 43,752 Intel
71 CORE I5-6600K CPU @ 3.50GHZ 4 10,523 42,092 Intel
72 XEON CPU E5-1620 0 @ 3.60GHZ 8 5,221 41,768 Intel
73 XEON CPU E3-1241 V3 @ 3.50GHZ 8 4,940 39,520 Intel
74 RYZEN 5 3400G 8 4,870 38,960 AMD
75 CORE I7-4770HQ CPU @ 2.20GHZ 8 4,852 38,816 Intel
76 CORE I5-4570S CPU @ 2.90GHZ 4 9,620 38,480 Intel
77 CORE I5-8250U CPU @ 1.60GHZ 8 4,800 38,400 Intel
78 CORE I5-8265U CPU @ 1.60GHZ 8 4,794 38,352 Intel
79 XEON CPU X5670 @ 2.93GHZ 12 3,185 38,220 Intel
80 CORE I7-3840QM CPU @ 2.80GHZ 8 4,643 37,144 Intel
81 CORE I3-8100 CPU @ 3.60GHZ 4 9,087 36,348 Intel
82 CORE I3-6100 CPU @ 3.70GHZ 4 8,996 35,984 Intel
83 CORE I7-4770K CPU @ 3.50GHZ 8 4,415 35,320 Intel
84 CORE I7-4850HQ CPU @ 2.30GHZ 8 4,312 34,496 Intel
85 CORE I5-3330 CPU @ 3.00GHZ 4 8,474 33,896 Intel
86 XEON CPU E5-2678 V3 @ 2.50GHZ 6 5,421 32,526 Intel
87 CORE I5-4570 CPU @ 3.20GHZ 4 7,997 31,988 Intel
88 CORE I5-3570 CPU @ 3.40GHZ 4 7,655 30,620 Intel
89 CORE I3-7100 CPU @ 3.90GHZ 4 7,234 28,936 Intel
90 CORE I7-2600 CPU @ 3.40GHZ 8 3,187 25,496 Intel
91 CORE I7-3610QM CPU @ 2.30GHZ 8 3,034 24,272 Intel
92 XEON CPU W3550 @ 3.07GHZ 8 2,962 23,696 Intel
93 RYZEN 3 3200G 4 5,356 21,424 AMD
94 CORE I7-8565U CPU @ 1.80GHZ 8 2,630 21,040 Intel
95 CORE I3-4130 CPU @ 3.40GHZ 4 4,896 19,584 Intel
96 CORE I5-6300U CPU @ 2.40GHZ 4 4,319 17,276 Intel
97 CORE I5-7200U CPU @ 2.50GHZ 4 4,031 16,124 Intel
98 CORE M3-7Y30 CPU @ 1.00GHZ 4 3,726 14,904 Intel
99 CORE2 QUAD CPU Q9550 @ 2.83GHZ 4 2,976 11,904 Intel
100 PENTIUM(R) GOLD G5400 CPU @ 3.70GHZ 4 2,748 10,992 Intel
101 CORE I3-3110M CPU @ 2.40GHZ 4 2,430 9,720 Intel
102 RYZEN 3 3200U 4 2,331 9,324 AMD
103 RYZEN 5 3500U 8 988 7,904 AMD
104 A10-6700 APU RADEON(TM) HD GRAPHICS 4 1,893 7,572 AMD
105 FX-8800P RADEON R7, 12 COMPUTE CORES 4C+8G 4 1,879 7,516 AMD
106 CORE2 DUO CPU E8400 @ 3.00GHZ 2 2,632 5,264 Intel
107 FX-4350 QUAD-CORE 4 1,213 4,852 AMD
108 CORE I5-9300H CPU @ 2.40GHZ 8 596 4,768 Intel
109 RYZEN 3 3250U 4 984 3,936 AMD
110 A8-6410 APU 4 430 1,720 AMD
111 ATOM(TM) X5-Z8350 CPU @ 1.44GHZ 4 255 1,020 Intel
112 PENTIUM(R) CPU G2020T @ 2.50GHZ 2 369 738 Intel