PROJECT #16955 RESEARCH FOR CANCER
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

This project simulations the dynamics of the human enzyme lactate dehydrogenase (LDH), the key metabolic enzyme that converts lactate to pyruvate and back.   We are simulating apo and holo-state dynamics to study how this enzyme binds inhibitors, which should lead to a better understanding of allostery and inform new computational drug discovery efforts.

PROJECT INFO

Manager(s): Prof. Vincent Voelz

Institution: Temple University

PROJECT WORK UNIT SUMMARY

Atoms: 151,566

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Thursday, 15 April 2021 21:02:47

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Thursday, 15 April 2021 21:02:47

Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make
1 RYZEN 9 5950X 16-CORE 32 48,323 1,546,336 AMD
2 RYZEN 9 3950X 16-CORE 32 25,843 826,976 AMD
3 RYZEN THREADRIPPER 2970WX 24-CORE 48 7,838 376,224 AMD
4 RYZEN 9 3900 12-CORE 24 13,345 320,280 AMD
5 RYZEN 7 3700X 8-CORE 16 16,813 269,008 AMD
6 XEON CPU E5-2667 V2 @ 3.30GHZ 32 7,647 244,704 Intel
7 RYZEN 5 5600X 6-CORE 12 17,190 206,280 AMD
8 RYZEN 7 3800X 8-CORE 16 10,704 171,264 AMD
9 RYZEN 5 3600 6-CORE 12 10,880 130,560 AMD
10 CORE I5-10400F CPU @ 2.90GHZ 12 6,903 82,836 Intel
11 RYZEN 5 2600 SIX-CORE 12 6,162 73,944 AMD
12 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 8,724 69,792 Intel
13 CORE I7-6700K CPU @ 4.00GHZ 8 7,031 56,248 Intel
14 CORE I5-7600 CPU @ 3.50GHZ 4 13,829 55,316 Intel
15 CORE I3-7100 CPU @ 3.90GHZ 4 7,456 29,824 Intel
16 CORE I7-8565U CPU @ 1.80GHZ 8 2,630 21,040 Intel
17 A8-6410 APU 4 432 1,728 AMD