Folding.LAR.Systems Folding.LAR.Systems Folding.LAR.Systems Folding.LAR.Systems
Research section Research projects and references
  1. Projects
  2. Research Project Folding Profile

Research: EBOLA Folding Project #16460

Project #16460 overview

Project Summary AI Beta

This project looks at a mutated part of the Ebola virus protein that stops it from working properly. The mutation prevents the virus from interacting with its own RNA, making it less dangerous. Scientists hope to use this information to design drugs that block the virus's activity in a similar way.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Sukrit Singh
Institution
Washington University in St. Louis

Work unit

Atoms
32,201
Core
GRO_A7
Status
Public

No related projects listed.

Source material

Official Project Description

This project simulates the F239A mutant of the immune inhibitory domain from the Ebola virus viral protein 35 (VP35), which is critical for viral infection.

This protein helps the virus escape detection inside human cells.

The F239A mutant being simulated here is unable to interact with other viral components such as RNA.

This makes its dynamics of particular interest such that if we can design a drug to affect protein function similarly to this mutation, we may be able to counteract the virus's effect.

Performance data

Hardware Performance for Project 16460

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:03:00

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN THREADRIPPER 3960X 24-CORE 48 13,936 668,928 AMD
2 RYZEN 9 3950X 16-CORE 32 16,072 514,304 AMD
3 RYZEN 9 5950X 16-CORE 32 14,531 464,992 AMD
4 RYZEN 9 5900X 12-CORE 24 17,026 408,624 AMD
5 RYZEN 9 3900XT 12-CORE 24 14,107 338,568 AMD
6 CORE I9-9980XE CPU @ 3.00GHZ 36 8,953 322,308 Intel
7 RYZEN THREADRIPPER 2970WX 24-CORE 48 6,343 304,464 AMD
8 RYZEN 9 3900X 12-CORE 24 10,863 260,712 AMD
9 CORE I9-9900K CPU @ 3.60GHZ 16 15,650 250,400 Intel
10 RYZEN 7 5800X 8-CORE 16 14,533 232,528 AMD
11 RYZEN THREADRIPPER 2950X 16-CORE 32 6,893 220,576 AMD
12 CORE I9-10900K CPU @ 3.70GHZ 20 10,651 213,020 Intel
13 RYZEN 7 3800X 8-CORE 16 10,463 167,408 AMD
14 CORE I9-7920X CPU @ 2.90GHZ 24 6,676 160,224 Intel
15 RYZEN THREADRIPPER 1920X 12-CORE 24 5,945 142,680 AMD
16 XEON W-2245 CPU @ 3.90GHZ 16 8,876 142,016 Intel
17 RYZEN 7 4800H 16 8,654 138,464 AMD
18 CORE I9-9900KF CPU @ 3.60GHZ 16 8,622 137,952 Intel
19 RYZEN 7 3700X 8-CORE 16 8,613 137,808 AMD
20 CORE I7-9700K CPU @ 3.60GHZ 8 16,324 130,592 Intel
21 RYZEN 5 3600X 6-CORE 12 10,449 125,388 AMD
22 RYZEN 5 3600 6-CORE 12 9,880 118,560 AMD
23 RYZEN 7 2700X EIGHT-CORE 16 6,970 111,520 AMD
24 XEON CPU E5-2660 0 @ 2.20GHZ 32 3,308 105,856 Intel
25 XEON CPU E5-2690 V2 @ 3.00GHZ 20 5,134 102,680 Intel
26 CORE I7-9700 CPU @ 3.00GHZ 8 11,441 91,528 Intel
27 CORE I7-8700K CPU @ 3.70GHZ 12 7,201 86,412 Intel
28 RYZEN 5 3600XT 6-CORE 12 7,069 84,828 AMD
29 CORE2 DUO CPU T7700 @ 2.40GHZ 12 6,732 80,784 Intel
30 RYZEN 5 3500 6-CORE 6 13,129 78,774 AMD
31 CORE I7-10710U CPU @ 1.10GHZ 12 6,033 72,396 Intel
32 CORE I7-8700 CPU @ 3.20GHZ 12 6,027 72,324 Intel
33 CORE I5-8400 CPU @ 2.80GHZ 6 11,775 70,650 Intel
34 RYZEN 5 2600X SIX-CORE 12 5,405 64,860 AMD
35 CORE I5-9400F CPU @ 2.90GHZ 6 9,978 59,868 Intel
36 XEON CPU E5-2620 V2 @ 2.10GHZ 24 2,437 58,488 Intel
37 RYZEN 7 1700 EIGHT-CORE 16 3,366 53,856 AMD
38 CORE I7-8550U CPU @ 1.80GHZ 8 6,434 51,472 Intel
39 CORE I7-6700K CPU @ 4.00GHZ 8 6,391 51,128 Intel
40 CORE I7-4790K CPU @ 4.00GHZ 8 5,912 47,296 Intel
41 CORE I7-8705G CPU @ 3.10GHZ 8 5,536 44,288 Intel
42 RYZEN 5 2600 SIX-CORE 12 3,638 43,656 AMD
43 CORE I5-5675R CPU @ 3.10GHZ 4 10,609 42,436 Intel
44 XEON CPU E3-1270 V5 @ 3.60GHZ 8 5,271 42,168 Intel
45 CORE I7-9850H CPU @ 2.60GHZ 12 3,395 40,740 Intel
46 CORE I5-7600 CPU @ 3.50GHZ 4 9,856 39,424 Intel
47 CORE I7-1068NG7 CPU @ 2.30GHZ 8 4,370 34,960 Intel
48 CORE I7-6700T CPU @ 2.80GHZ 8 4,206 33,648 Intel
49 CORE I5-6500 CPU @ 3.20GHZ 4 7,910 31,640 Intel
50 RYZEN 5 4600HS 12 2,471 29,652 AMD
51 CORE I9-8950HK CPU @ 2.90GHZ 12 2,213 26,556 Intel
52 CORE I7-3770 CPU @ 3.40GHZ 8 3,171 25,368 Intel
53 CORE I7-8565U CPU @ 1.80GHZ 8 2,803 22,424 Intel
54 FX-8350 EIGHT-CORE 8 2,671 21,368 AMD
55 CORE I7-9700F CPU @ 3.00GHZ 8 2,611 20,888 Intel
56 CORE I3-6100 CPU @ 3.70GHZ 4 4,260 17,040 Intel
57 CORE I3-7100 CPU @ 3.90GHZ 4 3,773 15,092 Intel
58 CORE I5-10210U CPU @ 1.60GHZ 7 2,035 14,245 Intel
59 PHENOM II X4 965 4 2,692 10,768 AMD
60 RYZEN 5 3500U 8 1,047 8,376 AMD
61 PENTIUM(R) SILVER N5000 CPU @ 1.10GHZ 4 1,938 7,752 Intel
62 FX-8320 EIGHT-CORE 8 955 7,640 AMD
63 CORE I3-6006U CPU @ 2.00GHZ 4 1,733 6,932 Intel
64 CELERON(R) CPU G3900 @ 2.80GHZ 2 3,113 6,226 Intel
65 CELERON(R) CPU G550 @ 2.60GHZ 2 1,630 3,260 Intel
66 A8-6410 APU 4 92 368 AMD