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Research: CANCER Folding Project #15501

Project #15501 overview

Project Summary AI Beta

This project studies small ring-shaped molecules that block HDAC8, a protein linked to cancer. By looking at how these molecules move and fit into HDAC8, researchers hope to better understand how they work as potential cancer treatments.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Prof. Vincent Voelz
Institution
Temple University

Work unit

Atoms
3,802
Core
0xa8
Status
Public

No related projects listed.

Source material

Official Project Description

This project simulates small macrocyclic inhibitors of HDAC8 (histone deacetylase 8), a therapeutic target for certain types of cancer.

This work, a collaboration with Kathryn Cole's group at Christopher Newport University, aims to understand the conformational flexibility of these ligands in solution and bound to the HDAC8 receptor.

Performance data

Hardware Performance for Project 15501

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Wednesday, 23 September 2026 18:29:18

CPU PPD Averages Beta

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 CORE I5-7400 CPU @ 3.00GHZ 4 19,797 79,188 Intel