PROJECT #14521 RESEARCH FOR Î’-LACTMASES
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
Beta lactamases are proteins which degrade penicillin and related antibiotics, enabling pathogenic bacteria to resist their effects.
We are modeling the dynamics of TEM-1 beta-lactamase to look for pockets in the protein which could bind small molecules and prevent it from functioning.
Drugs which could target these pockets could therefore help to treat drug resistant infections..
PROJECT INFO
Manager(s): Neha Vithani
Institution: Washington University in St. Louis
PROJECT WORK UNIT SUMMARY
Atoms: 34,514
Core: GRO_A7
Status: Public
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PPDDB data as of Tuesday, 31 January 2023 00:15:04