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PROJECT #17246 RESEARCH FOR IMMUNOGLOBULIN
FOLDING PERFORMANCE PROFILE

PROJECT SUMMARY

Beta lactamases are proteins which degrade penicillin and related antibiotics, enabling pathogenic bacteria to resist their effects.

We are modeling the dynamics of TEM-1 beta-lactamase to look for pockets in the protein which could bind small molecules and prevent it from functioning.

Drugs which could target these pockets could therefore help to treat drug resistant infections..

PROJECT INFO

Manager(s): Neha Vithani

Institution: Washington University in St. Louis

PROJECT WORK UNIT SUMMARY

Atoms: 34,218

Core: GRO_A8

Status: Public

PROJECT FOLDING PPD AVERAGES BY GPU

PPDDB data as of Wednesday, 29 March 2023 06:15:39

Rank
Project 		Model Name
Folding@Home Identifier 		Make
Brand 		GPU
Model 		PPD
Average 		Points WU
Average 		WUs Day
Average 		WU Time
Average

PROJECT FOLDING PPD AVERAGES BY CPU BETA

PPDDB data as of Wednesday, 29 March 2023 06:15:39

Rank
Project 		CPU Model Logical
Processors (LP) 		PPD-PLP
AVG PPD per 1 LP 		ALL LP-PPD
(Estimated) 		Make
1 RYZEN 9 3950X 16-CORE 32 21,289 681,248 AMD
2 RYZEN 9 5950X 16-CORE 32 20,113 643,616 AMD
3 RYZEN 7 5800X 8-CORE 16 35,961 575,376 AMD
4 12TH GEN CORE I7-12700K 20 19,494 389,880 Intel
5 CORE I9-10850K CPU @ 3.60GHZ 20 19,021 380,420 Intel
6 RYZEN 9 3900XT 12-CORE 24 14,731 353,544 AMD
7 11TH GEN CORE I9-11900K @ 3.50GHZ 16 21,547 344,752 Intel
8 RYZEN 9 3900 12-CORE 24 13,816 331,584 AMD
9 RYZEN THREADRIPPER 3960X 24-CORE 48 6,744 323,712 AMD
10 CORE I9-10900X CPU @ 3.70GHZ 20 16,143 322,860 Intel
11 RYZEN 7 3800X 8-CORE 16 16,009 256,144 AMD
12 XEON CPU E5-2680 V3 @ 2.50GHZ 24 9,623 230,952 Intel
13 CORE I9-9900 CPU @ 3.10GHZ 16 13,351 213,616 Intel
14 XEON CPU E5-2690 V4 @ 2.60GHZ 28 6,762 189,336 Intel
15 CORE I7-9700 CPU @ 3.00GHZ 8 23,400 187,200 Intel
16 CORE I7-8700 CPU @ 3.20GHZ 12 15,385 184,620 Intel
17 12TH GEN CORE I7-12700 20 8,329 166,580 Intel
18 RYZEN 5 2600X SIX-CORE 12 13,106 157,272 AMD
19 RYZEN THREADRIPPER 1920X 12-CORE 24 6,415 153,960 AMD
20 CORE I5-10400 CPU @ 2.90GHZ 12 12,750 153,000 Intel
21 RYZEN 5 3600 6-CORE 12 11,351 136,212 AMD
22 RYZEN 9 5900HS 16 7,602 121,632 AMD
23 RYZEN 7 2700X EIGHT-CORE 16 7,471 119,536 AMD
24 RYZEN 7 PRO 4750G 16 7,442 119,072 AMD
25 11TH GEN CORE I9-11900F @ 2.50GHZ 16 6,778 108,448 Intel
26 CORE I7-6700K CPU @ 4.00GHZ 8 13,191 105,528 Intel
27 CORE I7-10700T CPU @ 2.00GHZ 16 6,355 101,680 Intel
28 CORE I7-4790K CPU @ 4.00GHZ 8 12,147 97,176 Intel
29 11TH GEN CORE I5-11400 @ 2.60GHZ 12 6,782 81,384 Intel
30 RYZEN 5 2600 SIX-CORE 12 6,767 81,204 AMD
31 XEON CPU X5570 @ 2.93GHZ 16 5,051 80,816 Intel
32 11TH GEN CORE I7-1165G7 @ 2.80GHZ 8 9,843 78,744 Intel
33 CORE I7-10750H CPU @ 2.60GHZ 12 5,196 62,352 Intel
34 CORE I7-4790 CPU @ 3.60GHZ 8 7,718 61,744 Intel
35 11TH GEN CORE I5-1135G7 @ 2.40GHZ 8 7,591 60,728 Intel
36 CORE I7-5820K CPU @ 3.30GHZ 12 4,657 55,884 Intel
37 XEON W-10855M CPU @ 2.80GHZ 12 4,570 54,840 Intel
38 CORE I5-4590 CPU @ 3.30GHZ 4 12,854 51,416 Intel
39 CORE I7-4770HQ CPU @ 2.20GHZ 8 6,282 50,256 Intel
40 CORE I5-6600K CPU @ 3.50GHZ 4 12,529 50,116 Intel
41 XEON CPU E5-2680 0 @ 2.70GHZ 16 2,955 47,280 Intel
42 CORE I5-6500T CPU @ 2.50GHZ 4 10,443 41,772 Intel
43 RYZEN 5 1600 SIX-CORE 12 3,451 41,412 AMD
44 CORE I5-7600 CPU @ 3.50GHZ 4 10,206 40,824 Intel
45 CORE I7-4980HQ CPU @ 2.80GHZ 8 4,678 37,424 Intel
46 CORE I5-6600 CPU @ 3.30GHZ 4 9,212 36,848 Intel
47 RYZEN 3 3200G 4 9,062 36,248 AMD
48 CORE I7-3770 CPU @ 3.40GHZ 8 4,173 33,384 Intel
49 CORE I5-7400 CPU @ 3.00GHZ 4 7,856 31,424 Intel
50 CORE I3-6100 CPU @ 3.70GHZ 4 7,784 31,136 Intel
51 CORE I7-2600 CPU @ 3.40GHZ 8 3,826 30,608 Intel
52 XEON CPU E5-2620 0 @ 2.00GHZ 12 2,410 28,920 Intel
53 CORE I7-6700HQ CPU @ 2.60GHZ 8 3,241 25,928 Intel
54 CORE I5-2520M CPU @ 2.50GHZ 4 6,473 25,892 Intel
55 CORE I5-4690K CPU @ 3.50GHZ 4 6,044 24,176 Intel
56 CORE I5-7200U CPU @ 2.50GHZ 4 5,880 23,520 Intel
57 XEON CPU E5-1620 0 @ 3.60GHZ 8 2,904 23,232 Intel
58 CORE I5-3470 CPU @ 3.20GHZ 4 3,563 14,252 Intel
59 CORE I3-3240 CPU @ 3.40GHZ 4 3,547 14,188 Intel
60 CORE I5-4300U CPU @ 1.90GHZ 4 3,532 14,128 Intel
61 CORE I7 CPU 975 @ 3.33GHZ 8 1,597 12,776 Intel
62 CORE I3-6006U CPU @ 2.00GHZ 4 2,550 10,200 Intel
63 CORE I3-2120 CPU @ 3.30GHZ 4 1,933 7,732 Intel
64 CORE2 DUO CPU E8400 @ 3.00GHZ 2 2,484 4,968 Intel
65 FX-4300 QUAD-CORE 4 1,119 4,476 AMD
66 PENTIUM(R) CPU G2020T @ 2.50GHZ 2 1,436 2,872 Intel
67 A8-6410 APU 4 371 1,484 AMD