PROJECT #14377 RESEARCH FOR COVID-19
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
CORONAVIRUS PROJECT These projects are part of Folding@home’s efforts to assist researchers around the world taking up the global fight against COVID-19.
At the time of release, this is the latest news update: https://foldingathome.org/2020/03/10/covid19-update/ These projects are CPU projects to simulate COVID-19 proteins to learn about their dynamics and function.
These supplement high-priority GPU projects of the main protease as well as the COVID-19 receptor binding domains.
All can be considered potential drug targets. Please stay tuned to https://foldingathome.org/news/ for more current updates. 14300 series
- 14328 - Coronavirus SARS-CoV-2 main protease in complex with an inhibitor N3 (PDBID: 6lu7)
- 14329 - Coronavirus SARS-CoV-2 main protease in complex with an inhibitor N3 (PDBID: 6lu7)
- 14332 - SARS coronavirus spike receptor-binding domain complexed with its receptor ACE2 (PDB: 2ajf)
- 14333 - SARS-CoV-2 RBD domain in complex with human neutralizing S230 antibody Fab fragment (PDBs: 6nb8, 2ghv) [http://dx.doi.org/10.1016/j.cell.2018.12.028]
- 14334 - SARS-CoV-2 RBD domain in complex with human neutralizing S230 antibody Fab fragment (PDBs: 6nb8, 2ghv) [http://dx.doi.org/10.1016/j.cell.2018.12.028]
- 14335 - SARS-CoV-2 RBD domain in complex with human neutralizing S230 antibody Fab fragment (PDBs: 6nb8, 2ghv) [http://dx.doi.org/10.1016/j.cell.2018.12.028]
- 14336 -SARS-CoV-2 RBD domain in complex with human ACE2 receptor (PDB: 6vsb, 6acg)
- 14337 - FEP screening of Coronavirus SARS-CoV-2 main protease in complex with potential inhibitors (100_Ligands)
- 14338 - FEP screening of Coronavirus SARS-CoV-2 main protease in complex with potential inhibitors (100_Ligands)
- 14339 - FEP screening of potential protease inhibitors in solution (100_Ligands)
- 14340 - clone of 14332
- 14341 - clone of 14333
- 14342 - clone of 14334
- 14343 - clone of 14335
- 14344 - clone of 14336
- 14345 - clone of 14338
- 14346 - FEP screening of Coronavirus SARS-CoV-2 main protease in complex with potential inhibitors (7 fragment hits)
- 14347 - FEP screening of protease inhibitors in solution (7 fragment hits)
- 14348 - FEP screening of protease inhibitors in solution (7 fragment hits)
- 14349 - FEP screening of protease inhibitors in solution (72_L 1-100)
- 14350 - FEP screening of protease inhibitors in solution (72_L 101-200)
- 14351 - FEP screening of protease inhibitors in solution (72_L 201-300)
- 14352 - FEP screening of protease inhibitors in solution (72_L 301-400)
- 14353 - FEP screening of protease inhibitors in solution (72_L 401-500)
- 14354 - FEP screening of protease inhibitors in solution (72_L 501-600)
- 14355 - FEP screening of protease inhibitors in solution (72_L 601-700)
- 14356 - FEP screening of protease inhibitors in solution (72_L 701-800)
- 14357 - FEP screening of protease inhibitors in solution (72_L 801-900)
- 14358 - FEP screening of protease inhibitors in solution (72_L 901-1000)
- 14359 - FEP screening of protease inhibitors in solution (72_L 1001-1100)
- 14360 - FEP screening of protease inhibitors in solution (72_L 1101-1200)
- 14361 - FEP screening of protease inhibitors in solution (72_L 1201-1300)
- 14363 - FEP screening of protease inhibitors in complex (MOONSHOT 03-23 1-500 LR)
- 14364 - FEP screening of protease inhibitors in solution (MOONSHOT 03-23 1-500 L)
- 14365 - FEP screening of protease inhibitors in complex (MOONSHOT 03-26 1-1500 RL)
- 14366 - FEP screening of protease inhibitors in complex (MOONSHOT 03-26 1501-3000 RL)
- 14367 - FEP screening of protease inhibitors in complex (MOONSHOT 03-26 3001-4500 RL)
- 14368 - FEP screening of protease inhibitors in complex (MOONSHOT 03-26 4501-5660 RL)
- 14369 - FEP screening of protease inhibitors in solution (MOONSHOT 03-26 1-1500 L)
- 14370 - FEP screening of protease inhibitors in solution (MOONSHOT 03-26 1501-3000 L)
- 14371 - FEP screening of protease inhibitors in solution (MOONSHOT 03-26 3001-4500 L)
- 14372 - FEP screening of protease inhibitors in solution (MOONSHOT 03-26 4501-5660 L)
- 14373 - FEP screening of protease inhibitors in complex (MLTN 1-100 RL)
- 14374 - FEP screening of protease inhibitors in solution (MLTN 1-100 L)
- 14375 - FEP screening of protease inhibitors in complex (MS0331 1-2264 RL)
- 14376 - FEP screening of protease inhibitors in solution (MS0331 1-2264
- 14377 - FEP screening of protease inhibitors in complex (MS0406 1-428 RL)
- 14378 - FEP screening of protease inhibitors in solution (MS0406 1-428 L)
- 14379 - FEP screening of protease inhibitors in complex (MS0406-2 RL)
- 14380 - FEP screening of protease inhibitors in solution (MS0406-2 L)
- 14381-83 - FEP screening of protease inhibitors in complex (MSBR RL)
- 14384-86 - FEP screening of protease inhibitors in solution (MSBR L)
- 14399 - FEP screening of protease inhibitors in complex (MSBR RL)
- 14600 - FEP screening of protease inhibitors in complex (72_RL 1-100)
- 14601 - FEP screening of protease inhibitors in complex (72_RL 101-200)
- 14602 - FEP screening of protease inhibitors in complex (72_RL 201-300)
- 14603 - FEP screening of protease inhibitors in complex (72_RL 301-400)
- 14604 - FEP screening of protease inhibitors in complex (72_RL 401-500)
- 14605 - FEP screening of protease inhibitors in complex (72_RL 501-600)
- 14606 - FEP screening of protease inhibitors in complex (72_RL 601-700)
- 14607 - FEP screening of protease inhibitors in complex (72_RL 701-800)
- 14608 - FEP screening of protease inhibitors in complex (72_RL 801-900)
- 14609 - FEP screening of protease inhibitors in complex (72_RL 901-1000)
- 14610 - FEP screening of protease inhibitors in complex (72_RL 1001-1100)
- 14611 - FEP screening of protease inhibitors in complex (72_RL 1101-1200)
- 14612 - FEP screening of protease inhibitors in complex (72_RL 1201-1300)
- 14613 through 14628 - FEP screening of protease inhibitors in complex (AGG_RL)
- 14630 through 14643 - FEP screening of protease inhibitors in complex (AGG_RL)
- 14645 through 14656 - FEP screening of protease inhibitors in complex (387_RL)
- 14660 through 14671 - FEP screening of protease inhibitors in solution (387_L)
- 14676 - FEP screening of 20 fragment hits from DIAMOND UK in solution
PROJECT INFO
Manager(s): Prof. Vincent Voelz
Institution: Temple University
PROJECT WORK UNIT SUMMARY
Atoms: 55,560
Core: GRO_A7
Status: Public
PROJECT FOLDING PPD AVERAGES BY GPU
PPDDB data as of Tuesday, 07 February 2023 12:15:00
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
---|
PROJECT FOLDING PPD AVERAGES BY CPU BETA
PPDDB data as of Tuesday, 07 February 2023 12:15:00
Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
---|---|---|---|---|---|
1 | RYZEN 9 3950X 16-CORE | 32 | 13,600 | 435,200 | AMD |
2 | XEON CPU E5-2686 V4 @ 2.30GHZ | 36 | 7,304 | 262,944 | Intel |
3 | RYZEN 9 3900X 12-CORE | 24 | 9,960 | 239,040 | AMD |
4 | RYZEN 9 3900XT 12-CORE | 24 | 8,199 | 196,776 | AMD |
5 | RYZEN 7 3700X 8-CORE | 16 | 10,818 | 173,088 | AMD |
6 | CORE I9-10900X CPU @ 3.70GHZ | 20 | 8,505 | 170,100 | Intel |
7 | RYZEN 7 3800X 8-CORE | 16 | 9,757 | 156,112 | AMD |
8 | CORE I9-7940X CPU @ 3.10GHZ | 28 | 4,370 | 122,360 | Intel |
9 | RYZEN THREADRIPPER 1920X 12-CORE | 24 | 4,626 | 111,024 | AMD |
10 | RYZEN 5 3600 6-CORE | 12 | 8,822 | 105,864 | AMD |
11 | CORE I9-9880H CPU @ 2.30GHZ | 16 | 5,237 | 83,792 | Intel |
12 | XEON CPU E5-2660 0 @ 2.20GHZ | 32 | 2,615 | 83,680 | Intel |
13 | CORE I9-9900K CPU @ 3.60GHZ | 16 | 5,105 | 81,680 | Intel |
14 | RYZEN 5 2600X SIX-CORE | 12 | 6,153 | 73,836 | AMD |
15 | RYZEN 7 2700X EIGHT-CORE | 16 | 4,454 | 71,264 | AMD |
16 | CORE I5-4570 CPU @ 3.20GHZ | 4 | 6,894 | 27,576 | Intel |
17 | CORE I5-8400 CPU @ 2.80GHZ | 6 | 1,640 | 9,840 | Intel |
18 | CORE I3-3220 CPU @ 3.30GHZ | 4 | 969 | 3,876 | Intel |