PROJECT #14241 RESEARCH FOR G-PROTEINS
FOLDING PERFORMANCE PROFILE
PROJECT SUMMARY
G-proteins play central role in various signalling pathways involved in vision, taste, oflaction, muscle contraction and neurotransmission. G-proteins regulate these signalling pathways by switching between 'active' and 'inactive' states, dictated by the type nucleotide bound to their active site. When bound to gaunosine dinucleotide (GDP), G-proteins adopt inactive state. Dissociation of GDP and subsequent binding of gaunosine trinucleotide (GTP) activates G-proteins, which in turn activate downstream signalling pathways. GDP dissociation is the rate limiting step in activation of G-proteins and misregulation of this process can often lead to disease conditions. in this project, we are studying the mechanism of GDP dissociation process.
PROJECT INFO
Manager(s): Neha Vithani
Institution: Washington University in St. Louis
PROJECT WORK UNIT SUMMARY
Atoms: 57,431
Core: GRO_A7
Status: Public
PROJECT FOLDING PPD AVERAGES BY GPU
PPDDB data as of Monday, 25 January 2021 14:25:45
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Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
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PROJECT FOLDING PPD AVERAGES BY CPU BETA
PPDDB data as of Monday, 25 January 2021 14:25:45
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Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
|---|---|---|---|---|---|
| 1 | RYZEN 9 3950X 16-CORE | 32 | 18,316 | 586,112 | AMD |
| 2 | CORE I9-10980XE CPU @ 3.00GHZ | 36 | 7,036 | 253,296 | Intel |
| 3 | CORE I9-10900X CPU @ 3.70GHZ | 20 | 11,151 | 223,020 | Intel |
| 4 | RYZEN 7 3700X 8-CORE | 16 | 11,030 | 176,480 | AMD |
| 5 | RYZEN 7 3800X 8-CORE | 16 | 8,164 | 130,624 | AMD |
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