Research section Research projects and references

Research: CANCER Folding Project #12911

Project #12911 overview

Project Summary AI Beta

Proteins sometimes fold incorrectly due to changes in their code (mutations). This can cause diseases like cancer and Alzheimer's. The project relates to figuring out how these mutations affect protein folding so we can better understand and treat these diseases.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
Diego Kleiman
Institution
University of Illinois Urbana-Champaign

Work unit

Atoms
18,820
Core
0x22
Status
Public
Source material

Official Project Description

Protein misfolding occurs when a peptide cannot fold into its native structure.

Mutations in the protein sequence may cause alterations of the native folded conformation, leading to diseases such as cancer and Alzheimer's.

Understanding protein misfolding as a function of mutations is currently one of the biggest challenges in the biological sciences.

We aim to systematically study folding rates of diverse mutated proteins to better understand and predict folding dynamics.

Performance data

Hardware Performance for Project 12911

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:08:17

GPU PPD Averages

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average
1 GeForce RTX 2060
TU104 [GeForce RTX 2060]
Nvidia TU104 4,567,318 333,816 13.68 1 hrs 45 mins
2 GeForce RTX 2070
TU106 [GeForce RTX 2070]
Nvidia TU106 2,615,602 157,820 16.57 1 hrs 27 mins
3 GeForce RTX 2060 12GB
TU106 [GeForce RTX 2060 12GB]
Nvidia TU106 2,221,497 149,608 14.85 1 hrs 37 mins
4 GeForce RTX 2060
TU106 [Geforce RTX 2060]
Nvidia TU106 1,897,309 65,697 28.88 0 hrs 50 mins
5 GeForce RTX 3050 8GB
GA107 [GeForce RTX 3050 8GB]
Nvidia GA107 1,604,863 134,181 11.96 2 hrs 0 mins
6 GeForce GTX 1660 SUPER
TU116 [GeForce GTX 1660 SUPER]
Nvidia TU116 1,410,271 127,026 11.10 2 hrs 10 mins
7 GeForce GTX 1060 6GB
GP104 [GeForce GTX 1060 6GB]
Nvidia GP104 759,566 105,262 7.22 3 hrs 20 mins
8 GeForce GTX 1650
TU117 [GeForce GTX 1650]
Nvidia TU117 654,531 99,302 6.59 3 hrs 38 mins
9 Quadro T1000 Mobile
TU117GLM [Quadro T1000 Mobile]
Nvidia TU117GLM 542,934 26,000 20.88 1 hrs 9 mins
10 GeForce GTX 1050 Ti
GP107 [GeForce GTX 1050 Ti] 2138
Nvidia GP107 274,467 79,746 3.44 6 hrs 58 mins
11 GeForce GT 1030
GP108 [GeForce GT 1030]
Nvidia GP108 85,908 26,000 3.30 7 hrs 16 mins