Research section Research projects and references

Research: ALCHEMICAL-BINDING-FREE-ENERGY Folding Project #12600

Project #12600 overview

Project Summary AI Beta

People use alchemiscale.org to design experiments that calculate how strongly molecules bind together. These experiments are then run by computers through Folding@Home, a network of volunteers donating their computing power.
Automated summary; simplified and may not be fully accurate.

Project team

Manager(s)
David L. Dotson
Institution
Chodera Lab

Work unit

Atoms
10,000
Core
0x26
Status
Public
Source material

Official Project Description

Relative binding free energy calculations orchestrated via alchemiscale.org.

Networks of alchemical transformations are submitted by alchemiscale users, and transformations that can be performed by Folding@Home are executed via these PROJECTs.

Performance data

Hardware Performance for Project 12600

Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.

Data as of Sunday, 02 August 2026 22:08:34

GPU PPD Averages

Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average
1 P106-100
GP106 [P106-100]
Nvidia GP106 2,886,031 10,509 274.62 0 hrs 5 mins
2 GeForce GTX 1050 LP
GP107 [GeForce GTX 1050 LP] 1862
Nvidia GP107 1,727,395 2,625 658.06 0 hrs 2 mins
3 Tesla P4
GP104GL [Tesla P4] 5704
Nvidia GP104GL 1,696,220 18,755 90.44 0 hrs 16 mins
4 GeForce GTX 1050 Ti
GP107 [GeForce GTX 1050 Ti] 2138
Nvidia GP107 956,366 2,625 364.33 0 hrs 4 mins
5 Quadro P620
GP107GL [Quadro P620]
Nvidia GP107GL 754,675 18,865 40.00 0 hrs 36 mins
6 GeForce GTX 960
GM206 [GeForce GTX 960] 2308
Nvidia GM206 666,569 2,625 253.93 0 hrs 6 mins
7 RX 470/480/570/580/590
Ellesmere XT [RX 470/480/570/580/590]
AMD Ellesmere XT 410,669 14,143 29.04 0 hrs 50 mins
8 RX Vega M GL
Polaris 22 XL [RX Vega M GL]
AMD Polaris 22 XL 368,386 2,625 140.34 0 hrs 10 mins
9 Radeon R9 285/380
Tonga PRO [Radeon R9 285/380]
AMD Tonga PRO 332,299 14,742 22.54 1 hrs 4 mins
10 Ryzen 7000 Series iGPU
Raphael [Ryzen 7000 Series iGPU]
AMD Raphael 291,278 13,600 21.42 1 hrs 7 mins
11 GeForce GTX 980
GM204 [GeForce GTX 980] 4612
Nvidia GM204 274,577 2,625 104.60 0 hrs 14 mins
12 GeForce GTX 750 Ti
GM107 [GeForce GTX 750 Ti] 1389
Nvidia GM107 255,867 2,625 97.47 0 hrs 15 mins
13 GeForce GT 1030
GP108 [GeForce GT 1030]
Nvidia GP108 162,234 4,406 36.82 0 hrs 39 mins